17 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDKN1A	Cyclin dependent kinase inhibitor 1A. (164 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (421 aa)
	RNF141	Ring finger protein 141. (230 aa)
	LOC105499966	Uncharacterized protein. (489 aa)
	MKRN1	Makorin ring finger protein 1. (479 aa)
	MDM2	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	GSK3A	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	TSC2	TSC complex subunit 2. (1807 aa)
	BAD	BCL2 associated agonist of cell death. (167 aa)
	AKT1S1	AKT1 substrate 1. (276 aa)
	CDKN1B	Cyclin dependent kinase inhibitor 1B. (198 aa)
	MKRN2	Makorin ring finger protein 2. (416 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
	MKRN3	Uncharacterized protein. (182 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT1S1	ENSMNEP00000026038	ENSMNEP00000046002	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	AKT1 substrate 1.	0.968
AKT1	AKT2	ENSMNEP00000026038	ENSMNEP00000028923	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.975
AKT1	AKT3	ENSMNEP00000026038	ENSMNEP00000038984	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.932
AKT1	BAD	ENSMNEP00000026038	ENSMNEP00000044124	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCL2 associated agonist of cell death.	0.985
AKT1	CASP9	ENSMNEP00000026038	ENSMNEP00000016926	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caspase 9; Belongs to the peptidase C14A family.	0.942
AKT1	CDKN1A	ENSMNEP00000026038	ENSMNEP00000002098	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cyclin dependent kinase inhibitor 1A.	0.977
AKT1	CDKN1B	ENSMNEP00000026038	ENSMNEP00000015121	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cyclin dependent kinase inhibitor 1B.	0.980
AKT1	CHUK	ENSMNEP00000026038	ENSMNEP00000012804	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.985
AKT1	GSK3A	ENSMNEP00000026038	ENSMNEP00000030195	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.	0.999
AKT1	MDM2	ENSMNEP00000026038	ENSMNEP00000036531	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.998
AKT1	TSC2	ENSMNEP00000026038	ENSMNEP00000043671	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	TSC complex subunit 2.	0.953
AKT1S1	AKT1	ENSMNEP00000046002	ENSMNEP00000026038	AKT1 substrate 1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.968
AKT1S1	AKT2	ENSMNEP00000046002	ENSMNEP00000028923	AKT1 substrate 1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.951
AKT1S1	AKT3	ENSMNEP00000046002	ENSMNEP00000038984	AKT1 substrate 1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.951
AKT1S1	TSC2	ENSMNEP00000046002	ENSMNEP00000043671	AKT1 substrate 1.	TSC complex subunit 2.	0.520
AKT2	AKT1	ENSMNEP00000028923	ENSMNEP00000026038	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.975
AKT2	AKT1S1	ENSMNEP00000028923	ENSMNEP00000046002	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	AKT1 substrate 1.	0.951
AKT2	AKT3	ENSMNEP00000028923	ENSMNEP00000038984	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.935
AKT2	BAD	ENSMNEP00000028923	ENSMNEP00000044124	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCL2 associated agonist of cell death.	0.958
AKT2	CASP9	ENSMNEP00000028923	ENSMNEP00000016926	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caspase 9; Belongs to the peptidase C14A family.	0.914