STRINGSTRING
PIK3CB PIK3CB ENSMNEP00000000821 ENSMNEP00000000821 ENSMNEP00000001232 ENSMNEP00000001232 ENSMNEP00000001284 ENSMNEP00000001284 ENSMNEP00000001351 ENSMNEP00000001351 IGLV9-49 IGLV9-49 ENSMNEP00000001641 ENSMNEP00000001641 CYFIP1 CYFIP1 IGLV3-27 IGLV3-27 ELMO1 ELMO1 MYO5C MYO5C ACTG1 ACTG1 PLPP5 PLPP5 ACTR3 ACTR3 ACTL7B ACTL7B ENSMNEP00000002983 ENSMNEP00000002983 PLCG2 PLCG2 PLD1 PLD1 ENSMNEP00000004203 ENSMNEP00000004203 NCKIPSD NCKIPSD ENSMNEP00000004548 ENSMNEP00000004548 ACTRT1 ACTRT1 ENSMNEP00000004577 ENSMNEP00000004577 ENSMNEP00000004632 ENSMNEP00000004632 ENSMNEP00000004647 ENSMNEP00000004647 ARPC5L ARPC5L ITPR2 ITPR2 ENSMNEP00000005855 ENSMNEP00000005855 ENSMNEP00000005989 ENSMNEP00000005989 ENSMNEP00000006186 ENSMNEP00000006186 ENSMNEP00000006187 ENSMNEP00000006187 MYO5A MYO5A SRC SRC ENSMNEP00000006433 ENSMNEP00000006433 ENSMNEP00000006709 ENSMNEP00000006709 ENSMNEP00000006758 ENSMNEP00000006758 MYH9 MYH9 ABL1 ABL1 ENSMNEP00000007502 ENSMNEP00000007502 WIPF3 WIPF3 PIK3R2 PIK3R2 ABI2 ABI2 FYN FYN ENSMNEP00000008235 ENSMNEP00000008235 WASF3 WASF3 FMN2 FMN2 DSTN DSTN ENSMNEP00000008684 ENSMNEP00000008684 ENSMNEP00000008714 ENSMNEP00000008714 ENSMNEP00000009000 ENSMNEP00000009000 ENSMNEP00000009016 ENSMNEP00000009016 ENSMNEP00000009080 ENSMNEP00000009080 ENSMNEP00000009148 ENSMNEP00000009148 VAV3 VAV3 ENSMNEP00000009330 ENSMNEP00000009330 ENSMNEP00000009424 ENSMNEP00000009424 WASF1 WASF1 ENSMNEP00000010506 ENSMNEP00000010506 NCKAP1 NCKAP1 ENSMNEP00000011554 ENSMNEP00000011554 WIPF2 WIPF2 ENSMNEP00000011653 ENSMNEP00000011653 MAPK1 MAPK1 NCKAP1L NCKAP1L ENSMNEP00000012323 ENSMNEP00000012323 ENSMNEP00000012758 ENSMNEP00000012758 FMN1 FMN1 IGKV1-27 IGKV1-27 MYO1C MYO1C ENSMNEP00000014171 ENSMNEP00000014171 PLD3 PLD3 WASHC1 WASHC1 ENSMNEP00000014831 ENSMNEP00000014831 ENSMNEP00000014885 ENSMNEP00000014885 ENSMNEP00000015253 ENSMNEP00000015253 ENSMNEP00000015467 ENSMNEP00000015467 MAPK3 MAPK3 ENSMNEP00000015831 ENSMNEP00000015831 PRKCE PRKCE IGKV4-1 IGKV4-1 ENSMNEP00000016854 ENSMNEP00000016854 ENSMNEP00000017537 ENSMNEP00000017537 PLD2 PLD2 ARPC1B ARPC1B ENSMNEP00000018709 ENSMNEP00000018709 ACTR3B ACTR3B LOC105489886 LOC105489886 WASF2 WASF2 FCGR1A FCGR1A VAV1 VAV1 CFL1 CFL1 ENSMNEP00000020202 ENSMNEP00000020202 PIK3CA PIK3CA ACTB ACTB ENSMNEP00000020833 ENSMNEP00000020833 WAS WAS ENSMNEP00000021076 ENSMNEP00000021076 HSP90AB1 HSP90AB1 CDC42 CDC42 ENSMNEP00000021289 ENSMNEP00000021289 ELMO2 ELMO2 HSP90AA1 HSP90AA1 DOCK1 DOCK1 YES1 YES1 AHCYL1 AHCYL1 ARPC2 ARPC2 ENSMNEP00000023870 ENSMNEP00000023870 ITPR1 ITPR1 WASL WASL PLD4 PLD4 VAV2 VAV2 ENSMNEP00000024243 ENSMNEP00000024243 PTK2 PTK2 NCK1 NCK1 ENSMNEP00000025105 ENSMNEP00000025105 PLA2G6 PLA2G6 PLPP4 PLPP4 ITPR3 ITPR3 MYO1G MYO1G ENSMNEP00000026694 ENSMNEP00000026694 GRB2 GRB2 ENSMNEP00000027101 ENSMNEP00000027101 BTK BTK ELMO3 ELMO3 ENSMNEP00000028210 ENSMNEP00000028210 ENSMNEP00000028540 ENSMNEP00000028540 SYK SYK ENSMNEP00000029022 ENSMNEP00000029022 MYO1B MYO1B ACTL7A ACTL7A ACTRT2 ACTRT2 NF2 NF2 PIK3R1 PIK3R1 ENSMNEP00000030807 ENSMNEP00000030807 CD3G CD3G ENSMNEP00000031130 ENSMNEP00000031130 PRKCD PRKCD ENSMNEP00000031564 ENSMNEP00000031564 CFL2 CFL2 CRK CRK ENSMNEP00000032949 ENSMNEP00000032949 CYFIP2 CYFIP2 TRAV22 TRAV22 PLD5 PLD5 ENSMNEP00000036304 ENSMNEP00000036304 CD247 CD247 LIMK1 LIMK1 BAIAP2 BAIAP2 LYN LYN HCK HCK ENSMNEP00000038119 ENSMNEP00000038119 ENSMNEP00000038155 ENSMNEP00000038155 ENSMNEP00000038177 ENSMNEP00000038177 ENSMNEP00000038736 ENSMNEP00000038736 ABI1 ABI1 BRK1 BRK1 ENSMNEP00000039384 ENSMNEP00000039384 PLCG1 PLCG1 ENSMNEP00000040028 ENSMNEP00000040028 MYO1H MYO1H ENSMNEP00000041202 ENSMNEP00000041202 ENSMNEP00000041206 ENSMNEP00000041206 MYO1D MYO1D ENSMNEP00000041446 ENSMNEP00000041446 FGR FGR MYO10 MYO10 ACTR2 ACTR2 ENSMNEP00000043922 ENSMNEP00000043922 MYO9B MYO9B PAK1 PAK1 ENSMNEP00000044580 ENSMNEP00000044580 ACTL8 ACTL8 ENSMNEP00000045127 ENSMNEP00000045127 ARPC5 ARPC5 ARPC4 ARPC4 ENSMNEP00000045286 ENSMNEP00000045286 ARPC1A ARPC1A MYO1A MYO1A WIPF1 WIPF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
ENSMNEP00000000821Ig-like domain-containing protein. (143 aa)
ENSMNEP00000001232Uncharacterized protein. (117 aa)
ENSMNEP00000001284Ig-like domain-containing protein. (195 aa)
ENSMNEP00000001351Ig-like domain-containing protein. (151 aa)
IGLV9-49Immunoglobulin lambda variable 9-49. (124 aa)
ENSMNEP00000001641Ig-like domain-containing protein. (155 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
IGLV3-27Ig-like domain-containing protein. (167 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
MYO5CMyosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1743 aa)
ACTG1Actin gamma 1. (377 aa)
PLPP5Phospholipid phosphatase 5. (265 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
ENSMNEP00000002983Ig-like domain-containing protein. (137 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PLD1Phospholipase. (1074 aa)
ENSMNEP00000004203Ig-like domain-containing protein. (143 aa)
NCKIPSDNCK interacting protein with SH3 domain. (722 aa)
ENSMNEP00000004548Ig-like domain-containing protein. (170 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
ENSMNEP00000004577Ig-like domain-containing protein. (155 aa)
ENSMNEP00000004632Ig-like domain-containing protein. (151 aa)
ENSMNEP00000004647Uncharacterized protein. (185 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (159 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
ENSMNEP00000005855Ig-like domain-containing protein. (141 aa)
ENSMNEP00000005989Ig-like domain-containing protein. (155 aa)
ENSMNEP00000006186Uncharacterized protein. (184 aa)
ENSMNEP00000006187Ig-like domain-containing protein. (148 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1756 aa)
SRCTyrosine-protein kinase. (644 aa)
ENSMNEP00000006433Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa)
ENSMNEP00000006709Ig-like domain-containing protein. (137 aa)
ENSMNEP00000006758Ig-like domain-containing protein. (147 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
ENSMNEP00000007502Ig-like domain-containing protein. (144 aa)
WIPF3WAS/WASL interacting protein family member 3. (500 aa)
PIK3R2Uncharacterized protein. (668 aa)
ABI2Abl interactor 2. (513 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSMNEP00000008235Ig-like domain-containing protein. (148 aa)
WASF3WASP family member 3. (502 aa)
FMN2Formin 2. (1542 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
ENSMNEP00000008684Uncharacterized protein. (389 aa)
ENSMNEP00000008714Ig-like domain-containing protein. (197 aa)
ENSMNEP00000009000Ig-like domain-containing protein. (163 aa)
ENSMNEP00000009016Uncharacterized protein. (345 aa)
ENSMNEP00000009080Ig-like domain-containing protein. (138 aa)
ENSMNEP00000009148Ig-like domain-containing protein. (102 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
ENSMNEP00000009330Ig-like domain-containing protein. (125 aa)
ENSMNEP00000009424Ig-like domain-containing protein. (161 aa)
WASF1WASP family member 1. (559 aa)
ENSMNEP00000010506Ig-like domain-containing protein. (142 aa)
NCKAP1NCK associated protein 1. (1134 aa)
ENSMNEP00000011554Uncharacterized protein. (157 aa)
WIPF2WAS/WASL interacting protein family member 2. (246 aa)
ENSMNEP00000011653Ig-like domain-containing protein. (160 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
ENSMNEP00000012323Ig-like domain-containing protein. (125 aa)
ENSMNEP00000012758Ig-like domain-containing protein. (171 aa)
FMN1Formin 1. (1398 aa)
IGKV1-27Immunoglobulin kappa variable 1-27. (125 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (968 aa)
ENSMNEP00000014171Uncharacterized protein. (136 aa)
PLD3Phospholipase D family member 3. (490 aa)
WASHC1WASH complex subunit 1. (473 aa)
ENSMNEP00000014831HATPase_c domain-containing protein. (645 aa)
ENSMNEP00000014885Ig-like domain-containing protein. (146 aa)
ENSMNEP00000015253HATPase_c domain-containing protein. (688 aa)
ENSMNEP00000015467Uncharacterized protein. (312 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ENSMNEP00000015831Ig-like domain-containing protein. (151 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
IGKV4-1Immunoglobulin kappa variable 4-1. (168 aa)
ENSMNEP00000016854ADF-H domain-containing protein. (135 aa)
ENSMNEP00000017537Ig-like domain-containing protein. (151 aa)
PLD2Phospholipase. (933 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (375 aa)
ENSMNEP00000018709Ig-like domain-containing protein. (122 aa)
ACTR3BActin related protein 3B; Belongs to the actin family. (418 aa)
LOC105489886Ig-like domain-containing protein. (119 aa)
WASF2WASP family member 2. (499 aa)
FCGR1AUncharacterized protein. (357 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (196 aa)
ENSMNEP00000020202Ig-like domain-containing protein. (188 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ACTBActin beta. (379 aa)
ENSMNEP00000020833Ig-like domain-containing protein. (145 aa)
WASWASP actin nucleation promoting factor. (545 aa)
ENSMNEP00000021076Ig-like domain-containing protein. (167 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
CDC42Uncharacterized protein. (191 aa)
ENSMNEP00000021289Ig-like domain-containing protein. (182 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (823 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
YES1Tyrosine-protein kinase. (548 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
ENSMNEP00000023870Uncharacterized protein. (152 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
PLD4Phospholipase D family member 4. (515 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
ENSMNEP00000024243Ig-like domain-containing protein. (139 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa)
NCK1Cytoplasmic protein. (377 aa)
ENSMNEP00000025105Ig-like domain-containing protein. (186 aa)
PLA2G6Phospholipase A2 group VI. (836 aa)
PLPP4Phospholipid phosphatase 4. (271 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
ENSMNEP00000026694Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (353 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSMNEP00000027101IGv domain-containing protein. (102 aa)
BTKTyrosine-protein kinase. (659 aa)
ELMO3Engulfment and cell motility 3. (761 aa)
ENSMNEP00000028210Ig-like domain-containing protein. (141 aa)
ENSMNEP00000028540Uncharacterized protein. (139 aa)
SYKTyrosine-protein kinase. (629 aa)
ENSMNEP00000029022Uncharacterized protein. (185 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1136 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (377 aa)
NF2Neurofibromin 2. (595 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSMNEP00000030807Uncharacterized protein. (120 aa)
CD3GCD3g molecule. (209 aa)
ENSMNEP00000031130Ig-like domain-containing protein. (162 aa)
PRKCDProtein kinase C. (729 aa)
ENSMNEP00000031564Ig-like domain-containing protein. (148 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
ENSMNEP00000032949Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (164 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
TRAV22T cell receptor alpha variable 22. (147 aa)
PLD5Phospholipase D family member 5. (514 aa)
ENSMNEP00000036304Ig-like domain-containing protein. (152 aa)
CD247CD247 molecule. (164 aa)
LIMK1LIM domain kinase 1. (677 aa)
BAIAP2BAI1 associated protein 2. (552 aa)
LYNTyrosine-protein kinase. (512 aa)
HCKTyrosine-protein kinase. (504 aa)
ENSMNEP00000038119Uncharacterized protein. (117 aa)
ENSMNEP00000038155Uncharacterized protein. (314 aa)
ENSMNEP00000038177Uncharacterized protein; Belongs to the actin family. (156 aa)
ENSMNEP00000038736Uncharacterized protein. (67 aa)
ABI1Abl interactor 1. (508 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
ENSMNEP00000039384Ig-like domain-containing protein. (130 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
ENSMNEP00000040028Ig-like domain-containing protein. (162 aa)
MYO1HMyosin IH; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1037 aa)
ENSMNEP00000041202ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (209 aa)
ENSMNEP00000041206Uncharacterized protein; Belongs to the actin family. (163 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
ENSMNEP00000041446Uncharacterized protein. (60 aa)
FGRTyrosine-protein kinase. (529 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2019 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
ENSMNEP00000043922Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (133 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2135 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
ENSMNEP00000044580Ig-like domain-containing protein. (192 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
ENSMNEP00000045127Uncharacterized protein. (183 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ARPC4Uncharacterized protein. (78 aa)
ENSMNEP00000045286Ig-like domain-containing protein. (134 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
WIPF1WAS/WASL interacting protein family member 1. (510 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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