STRINGSTRING
H2AJ H2AJ H2BC5 H2BC5 LOC105499682 LOC105499682 ENSMNEP00000004997 ENSMNEP00000004997 LOC105482586 LOC105482586 LOC105482579-2 LOC105482579-2 H2AX H2AX LOC105491665 LOC105491665 H3-4 H3-4 LOC105482573 LOC105482573 LOC105499748 LOC105499748 RAD50 RAD50 ENSMNEP00000024768 ENSMNEP00000024768 ENSMNEP00000025137 ENSMNEP00000025137 CDK2 CDK2 LOC105499692 LOC105499692 ENSMNEP00000042823 ENSMNEP00000042823 LMNB2 LMNB2 NBN NBN CABIN1 CABIN1 TP53 TP53 LOC105491641 LOC105491641 LOC105481870 LOC105481870 H2BC15 H2BC15 H2AZ1 H2AZ1 ENSMNEP00000001463 ENSMNEP00000001463 HMGA1 HMGA1 ATM ATM H2BC14 H2BC14 ENSMNEP00000000889 ENSMNEP00000000889 LOC105466836 LOC105466836 LOC105491644 LOC105491644 CCNA2 CCNA2 TERF2 TERF2 ENSMNEP00000033662 ENSMNEP00000033662 ENSMNEP00000044636 ENSMNEP00000044636 HIRA HIRA TERF2IP TERF2IP H2AC7 H2AC7 H2BC6 H2BC6 LOC105497787 LOC105497787 H1-5 H1-5 EP400 EP400 H2BC8 H2BC8 ENSMNEP00000003373 ENSMNEP00000003373 SRCAP SRCAP LOC105482579 LOC105482579 ACD ACD ENSMNEP00000012828 ENSMNEP00000012828 RB1 RB1 POT1 POT1 MRE11 MRE11 UBN1 UBN1 ASF1B ASF1B CCNA1 CCNA1 H1-0 H1-0 LOC105482587 LOC105482587 H2AC20 H2AC20 CDK3 CDK3 ENSMNEP00000006547 ENSMNEP00000006547 LOC105482560 LOC105482560 H2BC3 H2BC3 ENSMNEP00000002194 ENSMNEP00000002194 CDKN1A CDKN1A H1-4 H1-4 H2BC1 H2BC1 LOC105491634 LOC105491634 LOC105478980 LOC105478980 H2BU1 H2BU1 LOC105499746 LOC105499746 CDKN1B CDKN1B ASF1A ASF1A TINF2 TINF2 ENSMNEP00000020368 ENSMNEP00000020368 TERF1 TERF1 LMNB1 LMNB1 H2AZ2 H2AZ2 CCNE2 CCNE2 KAT5 KAT5 HMGA2 HMGA2 H2BC11 H2BC11 H2AC6 H2AC6 CCNE1 CCNE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105499682Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSMNEP00000004997annotation not available (103 aa)
LOC105482586Histone H4. (103 aa)
LOC105482579-2Histone H2B type 1. (126 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
LOC105491665Histone H4. (103 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
LOC105482573Histone H4. (103 aa)
LOC105499748Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
RAD50Zinc-hook domain-containing protein. (1355 aa)
ENSMNEP00000024768Histone H2A; Belongs to the histone H2A family. (126 aa)
ENSMNEP00000025137EP400_N domain-containing protein. (401 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
LOC105499692Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
ENSMNEP00000042823Uncharacterized protein. (143 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (601 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa)
CABIN1Calcineurin binding protein 1. (2218 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (270 aa)
LOC105491641Uncharacterized LOC105491641. (103 aa)
LOC105481870Histone H4. (103 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (166 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
ENSMNEP00000001463annotation not available (103 aa)
HMGA1Uncharacterized protein. (201 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3032 aa)
H2BC14Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSMNEP00000000889annotation not available (103 aa)
LOC105466836Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
LOC105491644Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
TERF2Telomeric repeat binding factor 2. (542 aa)
ENSMNEP00000033662Uncharacterized protein. (179 aa)
ENSMNEP00000044636Histone H2A; Belongs to the histone H2A family. (102 aa)
HIRAProtein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1017 aa)
TERF2IPTERF2 interacting protein. (400 aa)
H2AC7Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC6Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105497787Histone H2B; Belongs to the histone H2B family. (126 aa)
H1-5Histone cluster 1 H1 family member b. (226 aa)
EP400E1A binding protein p400. (3116 aa)
H2BC8Histone H2B type 1. (126 aa)
ENSMNEP00000003373Uncharacterized protein. (105 aa)
SRCAPUncharacterized protein. (3229 aa)
LOC105482579Histone H2B type 1. (126 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (518 aa)
ENSMNEP00000012828Histone H2B; Belongs to the histone H2B family. (129 aa)
RB1RB transcriptional corepressor 1. (928 aa)
POT1Protection of telomeres 1. (634 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa)
UBN1Ubinuclein 1. (1131 aa)
ASF1BAnti-silencing function 1B histone chaperone. (202 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
H1-0H1 histone family member 0. (194 aa)
LOC105482587Uncharacterized LOC105482587. (103 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (333 aa)
ENSMNEP00000006547annotation not available (103 aa)
LOC105482560Histone domain-containing protein; Belongs to the histone H2B family. (127 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSMNEP00000002194annotation not available (103 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
H1-4Histone cluster 1 H1 family member e. (219 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC105491634Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105478980Histone H4. (103 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105499746Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ASF1AAnti-silencing function 1A histone chaperone. (204 aa)
TINF2TERF1 interacting nuclear factor 2. (451 aa)
ENSMNEP00000020368Uncharacterized protein. (80 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (438 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (407 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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