STRINGSTRING
TGFB1I1 TGFB1I1 PARVA PARVA RSU1 RSU1 RNF222 RNF222 ARHGEF6 ARHGEF6 PARVB PARVB TESK2 TESK2 LIMS1 LIMS1 ENSMNEP00000011912 ENSMNEP00000011912 LPXN LPXN ACTN1 ACTN1 PXN PXN TESK1 TESK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (467 aa)
PARVAParvin alpha. (372 aa)
RSU1Ras suppressor protein 1. (277 aa)
RNF222Ring finger protein 222. (220 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (776 aa)
PARVBParvin beta. (397 aa)
TESK2Testis associated actin remodelling kinase 2. (572 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (398 aa)
ENSMNEP00000011912Uncharacterized protein. (102 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
ACTN1Actinin alpha 1. (914 aa)
PXNPaxillin. (1082 aa)
TESK1Testis associated actin remodelling kinase 1. (626 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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