STRINGSTRING
CASP1 CASP1 CCDC71L CCDC71L NFKB1 NFKB1 NFKB2 NFKB2 GSDMD GSDMD CASP12 CASP12 CTSG CTSG RELA RELA IL1B IL1B IL1A IL1A LOC105493689 LOC105493689
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CASP1Caspase 1; Belongs to the peptidase C14A family. (442 aa)
CCDC71LCoiled-coil domain containing 71 like. (235 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
GSDMDGasdermin D. (523 aa)
CASP12Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (408 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (224 aa)
LOC105493689Uncharacterized protein; Belongs to the peptidase C14A family. (410 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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