STRINGSTRING
ENSMNEP00000000174 ENSMNEP00000000174 PSME3 PSME3 PSMA1 PSMA1 PSMD7 PSMD7 PSMA6 PSMA6 LOC105475719 LOC105475719 ENSMNEP00000002753 ENSMNEP00000002753 PSMC2 PSMC2 ENSMNEP00000004083 ENSMNEP00000004083 ENSMNEP00000004092 ENSMNEP00000004092 PSMD1 PSMD1 GLI3 GLI3 ENSMNEP00000004441 ENSMNEP00000004441 ENSMNEP00000005796 ENSMNEP00000005796 ENSMNEP00000005892 ENSMNEP00000005892 GSK3B GSK3B PSMA7 PSMA7 ENSMNEP00000007101 ENSMNEP00000007101 PSME1 PSME1 PSMD6 PSMD6 ENSMNEP00000007573 ENSMNEP00000007573 PSMB10 PSMB10 PSMB4 PSMB4 ENSMNEP00000008415 ENSMNEP00000008415 ENSMNEP00000008478 ENSMNEP00000008478 ENSMNEP00000010116 ENSMNEP00000010116 PSMA8 PSMA8 ENSMNEP00000010989 ENSMNEP00000010989 PSMC4 PSMC4 ENSMNEP00000011567 ENSMNEP00000011567 PSME4 PSME4 PSMD9 PSMD9 PSME2 PSME2 PSMD8 PSMD8 PSMD3 PSMD3 PSMD12 PSMD12 SKP1 SKP1 PSMD11 PSMD11 ENSMNEP00000017273 ENSMNEP00000017273 UBA52 UBA52 ENSMNEP00000019162 ENSMNEP00000019162 PSMA5 PSMA5 SUFU SUFU CSNK1A1L CSNK1A1L ENSMNEP00000021101 ENSMNEP00000021101 PSMB1 PSMB1 PSMB7 PSMB7 ENSMNEP00000022472 ENSMNEP00000022472 PSMB6 PSMB6 ENSMNEP00000023008 ENSMNEP00000023008 PSMA3 PSMA3 CUL1 CUL1 PSMC5 PSMC5 CSNK1A1 CSNK1A1 PSMD2 PSMD2 PSMA4 PSMA4 RPS27A RPS27A PSMB3 PSMB3 PSMD14 PSMD14 RBX1 RBX1 PSMB9 PSMB9 PRKACB PRKACB PSMC1 PSMC1 PSMD13 PSMD13 PSMD5 PSMD5 ENSMNEP00000035304 ENSMNEP00000035304 ENSMNEP00000036101 ENSMNEP00000036101 PSMF1 PSMF1 ENSMNEP00000036869 ENSMNEP00000036869 ENSMNEP00000038934 ENSMNEP00000038934 PSMB2 PSMB2 PSMD4 PSMD4 PSMA2 PSMA2 PSMD10 PSMD10 ENSMNEP00000041258 ENSMNEP00000041258 PRKACA PRKACA ENSMNEP00000042218 ENSMNEP00000042218 ENSMNEP00000042381 ENSMNEP00000042381 BTRC BTRC ENSMNEP00000042738 ENSMNEP00000042738 PSMB5 PSMB5 PSMC3 PSMC3 PSMB8 PSMB8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000000174AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
PSME3Proteasome activator subunit 3. (265 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
LOC105475719Ubiquitin-like domain-containing protein. (127 aa)
ENSMNEP00000002753Ubiquitin-like domain-containing protein. (156 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa)
ENSMNEP00000004083Ubiquitin-like domain-containing protein. (127 aa)
ENSMNEP00000004092Proteasome subunit alpha type. (231 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa)
GLI3GLI family zinc finger 3. (1580 aa)
ENSMNEP0000000444126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa)
ENSMNEP00000005796Ribosomal_S27 domain-containing protein. (137 aa)
ENSMNEP00000005892Ubiquitin-like domain-containing protein. (156 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
ENSMNEP00000007101Uncharacterized protein. (191 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ENSMNEP00000007573MPN domain-containing protein. (149 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
ENSMNEP00000008415Ubiquitin-like domain-containing protein. (83 aa)
ENSMNEP00000008478Ubiquitin-like domain-containing protein. (120 aa)
ENSMNEP00000010116CSN8_PSD8_EIF3K domain-containing protein. (243 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ENSMNEP00000010989Proteasome endopeptidase complex. (241 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ENSMNEP00000011567Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa)
PSME4Proteasome activator subunit 4. (1844 aa)
PSMD9PDZ domain-containing protein. (223 aa)
PSME2Proteasome activator subunit 2. (254 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (469 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
ENSMNEP00000017273Protein kinase domain-containing protein. (311 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ENSMNEP00000019162AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (526 aa)
CSNK1A1LCasein kinase 1 alpha 1 like. (243 aa)
ENSMNEP00000021101Zf-rbx1 domain-containing protein. (93 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSMNEP00000022472AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
PSMB6Proteasome subunit beta. (285 aa)
ENSMNEP00000023008ANK_REP_REGION domain-containing protein. (159 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
RBX1RING-type domain-containing protein. (108 aa)
PSMB9Proteasome subunit beta. (219 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (339 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (493 aa)
ENSMNEP00000035304Ubiquitin-like domain-containing protein. (134 aa)
ENSMNEP00000036101Uncharacterized protein. (167 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
ENSMNEP00000036869Uncharacterized protein. (97 aa)
ENSMNEP00000038934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (403 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSMNEP00000041258Prot_ATP_ID_OB domain-containing protein. (166 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ENSMNEP00000042218Uncharacterized protein; Belongs to the SKP1 family. (171 aa)
ENSMNEP00000042381Uncharacterized protein. (312 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
ENSMNEP00000042738Uncharacterized protein. (394 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa)
PSMB8Proteasome subunit beta. (276 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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