85 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSMNEP00000001974	WD_REPEATS_REGION domain-containing protein. (415 aa)
	H2BC1	Histone H2B; Belongs to the histone H2B family. (127 aa)
	LOC105491634	Histone H2B; Belongs to the histone H2B family. (126 aa)
	LOC105478980	Histone H4. (103 aa)
	H2BU1	Histone H2B; Belongs to the histone H2B family. (126 aa)
	LOC112422912	Histone H2B; Belongs to the histone H2B family. (126 aa)
	LOC105491644	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	LOC105466836	Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
	ENSMNEP00000000889	annotation not available (103 aa)
	H2BC14	Histone H2B; Belongs to the histone H2B family. (126 aa)
	CENPI	Centromere protein I. (755 aa)
	ENSMNEP00000001463	annotation not available (103 aa)
	CENPK	Centromere protein K. (269 aa)
	CENPM	Centromere protein M. (180 aa)
	ENSMNEP00000044636	Histone H2A; Belongs to the histone H2A family. (102 aa)
	CENPO	Centromere protein O. (281 aa)
	CENPH	Centromere protein H. (247 aa)
	RBBP4	RB binding protein 4, chromatin remodeling factor. (425 aa)
	RSF1	Remodeling and spacing factor 1. (1441 aa)
	CENPQ	Centromere protein Q. (268 aa)
	SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1070 aa)
	ENSMNEP00000037489	Uncharacterized protein. (254 aa)
	CENPX	Centromere protein X. (132 aa)
	CENPP	Centromere protein P. (288 aa)
	HJURP	Holliday junction recognition protein. (728 aa)
	NPM1	Nucleophosmin 1. (294 aa)
	CENPC	Centromere protein C. (945 aa)
	LOC105491641	Uncharacterized LOC105491641. (103 aa)
	LOC105481870	Histone H4. (103 aa)
	CENPT	Centromere protein T. (561 aa)
	CENPN	Centromere protein N. (345 aa)
	H2BC15	Histone H2B; Belongs to the histone H2B family. (166 aa)
	H2AZ1	Histone H2A; Belongs to the histone H2A family. (128 aa)
	ENSMNEP00000024768	Histone H2A; Belongs to the histone H2A family. (126 aa)
	ENSMNEP00000024169	Nucleoplasmin domain-containing protein. (220 aa)
	H2AZ2	Histone H2A; Belongs to the histone H2A family. (128 aa)
	ENSMNEP00000022556	Histone H2B; Belongs to the histone H2B family. (134 aa)
	ENSMNEP00000022200	Uncharacterized protein. (232 aa)
	CENPU	Centromere protein U. (422 aa)
	CENPL	Centromere protein L. (390 aa)
	ENSMNEP00000019698	WD_REPEATS_REGION domain-containing protein. (381 aa)
	ENSMNEP00000016207	Uncharacterized protein. (253 aa)
	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa)
	CENPW	Centromere protein W. (91 aa)
	RBBP7	RB binding protein 7, chromatin remodeling factor. (469 aa)
	ENSMNEP00000012828	Histone H2B; Belongs to the histone H2B family. (129 aa)
	ENSMNEP00000012372	WD_REPEATS_REGION domain-containing protein. (406 aa)
	ENSMNEP00000012292	Uncharacterized protein. (208 aa)
	ENSMNEP00000012230	Uncharacterized protein. (216 aa)
	RUVBL1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
	ITGB3BP	Integrin subunit beta 3 binding protein. (216 aa)
	OIP5	Opa interacting protein 5. (188 aa)
	KNL1	Kinetochore scaffold 1. (2276 aa)
	MIS18A	MIS18 kinetochore protein A. (232 aa)
	LOC105482587	Uncharacterized LOC105482587. (103 aa)
	H2AC20	Histone H2A; Belongs to the histone H2A family. (129 aa)
	ENSMNEP00000006547	annotation not available (103 aa)
	H2AJ	Histone H2A; Belongs to the histone H2A family. (129 aa)
	CENPA	Centromere protein A. (138 aa)
	H2BC5	Histone H2B; Belongs to the histone H2B family. (126 aa)
	LOC105499682	Histone H2B; Belongs to the histone H2B family. (126 aa)
	ENSMNEP00000004997	annotation not available (103 aa)
	LOC105482586	Histone H4. (103 aa)
	LOC105482579-2	Histone H2B type 1. (126 aa)
	H2AX	Histone H2A; Belongs to the histone H2A family. (143 aa)
	LOC105491665	Histone H4. (103 aa)
	LOC105482573	Histone H4. (103 aa)
	ENSMNEP00000004093	Uncharacterized protein. (305 aa)
	H2AC6	Histone H2A; Belongs to the histone H2A family. (130 aa)
	H2BC11	Histone H2B; Belongs to the histone H2B family. (126 aa)
	ENSMNEP00000003725	Nucleoplasmin domain-containing protein. (218 aa)
	ENSMNEP00000003706	Histone H2B; Belongs to the histone H2B family. (136 aa)
	LOC105482579	Histone H2B type 1. (126 aa)
	ENSMNEP00000003373	Uncharacterized protein. (105 aa)
	H2BC8	Histone H2B type 1. (126 aa)
	ENSMNEP00000002894	WD_REPEATS_REGION domain-containing protein. (419 aa)
	LOC105497787	Histone H2B; Belongs to the histone H2B family. (126 aa)
	H2BC6	Histone H2B; Belongs to the histone H2B family. (126 aa)
	H2AC7	Histone H2A; Belongs to the histone H2A family. (130 aa)
	ENSMNEP00000002323	WD_REPEATS_REGION domain-containing protein. (380 aa)
	MIS18BP1	MIS18 binding protein 1. (1131 aa)
	LOC105482560	Histone domain-containing protein; Belongs to the histone H2B family. (127 aa)
	H2AC14	Histone H2A; Belongs to the histone H2A family. (128 aa)
	H2BC3	Histone H2B; Belongs to the histone H2B family. (126 aa)
	ENSMNEP00000002194	annotation not available (103 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CENPA	CENPC	ENSMNEP00000005514	ENSMNEP00000029503	Centromere protein A.	Centromere protein C.	0.934
CENPA	CENPH	ENSMNEP00000005514	ENSMNEP00000043239	Centromere protein A.	Centromere protein H.	0.943
CENPA	CENPI	ENSMNEP00000005514	ENSMNEP00000001205	Centromere protein A.	Centromere protein I.	0.945
CENPA	CENPK	ENSMNEP00000005514	ENSMNEP00000045443	Centromere protein A.	Centromere protein K.	0.949
CENPA	CENPL	ENSMNEP00000005514	ENSMNEP00000019979	Centromere protein A.	Centromere protein L.	0.893
CENPA	CENPM	ENSMNEP00000005514	ENSMNEP00000045250	Centromere protein A.	Centromere protein M.	0.974
CENPA	CENPN	ENSMNEP00000005514	ENSMNEP00000028422	Centromere protein A.	Centromere protein N.	0.978
CENPA	CENPP	ENSMNEP00000005514	ENSMNEP00000035090	Centromere protein A.	Centromere protein P.	0.881
CENPA	CENPQ	ENSMNEP00000005514	ENSMNEP00000040384	Centromere protein A.	Centromere protein Q.	0.918
CENPA	CENPT	ENSMNEP00000005514	ENSMNEP00000028545	Centromere protein A.	Centromere protein T.	0.962
CENPA	CENPU	ENSMNEP00000005514	ENSMNEP00000022045	Centromere protein A.	Centromere protein U.	0.955
CENPA	CENPW	ENSMNEP00000005514	ENSMNEP00000014326	Centromere protein A.	Centromere protein W.	0.950
CENPA	CENPX	ENSMNEP00000005514	ENSMNEP00000036492	Centromere protein A.	Centromere protein X.	0.827
CENPA	ENSMNEP00000000889	ENSMNEP00000005514	ENSMNEP00000000889	Centromere protein A.	annotation not available	0.746
CENPA	ENSMNEP00000001463	ENSMNEP00000005514	ENSMNEP00000001463	Centromere protein A.	annotation not available	0.746
CENPA	ENSMNEP00000001974	ENSMNEP00000005514	ENSMNEP00000001974	Centromere protein A.	WD_REPEATS_REGION domain-containing protein.	0.488
CENPA	ENSMNEP00000002194	ENSMNEP00000005514	ENSMNEP00000002194	Centromere protein A.	annotation not available	0.746
CENPA	ENSMNEP00000002323	ENSMNEP00000005514	ENSMNEP00000002323	Centromere protein A.	WD_REPEATS_REGION domain-containing protein.	0.488
CENPA	ENSMNEP00000002894	ENSMNEP00000005514	ENSMNEP00000002894	Centromere protein A.	WD_REPEATS_REGION domain-containing protein.	0.488
CENPA	ENSMNEP00000003373	ENSMNEP00000005514	ENSMNEP00000003373	Centromere protein A.	Uncharacterized protein.	0.590