STRINGSTRING
UBA52 UBA52 CDK7 CDK7 CCNE1 CCNE1 PSMA7 PSMA7 CDK3 CDK3 ENSMNEP00000007101 ENSMNEP00000007101 PSME1 PSME1 PSMD6 PSMD6 ENSMNEP00000007573 ENSMNEP00000007573 PTK6 PTK6 PSMB10 PSMB10 PSMB4 PSMB4 ENSMNEP00000008415 ENSMNEP00000008415 CABLES1 CABLES1 CCNA1 CCNA1 ENSMNEP00000008478 ENSMNEP00000008478 ENSMNEP00000010116 ENSMNEP00000010116 LIN54 LIN54 CKS1B CKS1B SKP2 SKP2 TFDP1 TFDP1 PSMB8 PSMB8 PSMC3 PSMC3 CDK2 CDK2 PSMB5 PSMB5 LIN52 LIN52 ENSMNEP00000042738 ENSMNEP00000042738 RBBP4 RBBP4 ENSMNEP00000042381 ENSMNEP00000042381 ENSMNEP00000042218 ENSMNEP00000042218 ENSMNEP00000041258 ENSMNEP00000041258 PSMD10 PSMD10 PSMA2 PSMA2 PSMD4 PSMD4 PSMB2 PSMB2 ENSMNEP00000039425 ENSMNEP00000039425 AKT3 AKT3 ENSMNEP00000038934 ENSMNEP00000038934 CCNH CCNH ENSMNEP00000036869 ENSMNEP00000036869 PSMF1 PSMF1 ENSMNEP00000036101 ENSMNEP00000036101 WEE1 WEE1 ENSMNEP00000035304 ENSMNEP00000035304 CCND1 CCND1 PSMD5 PSMD5 PSMD13 PSMD13 TFDP2 TFDP2 ENSMNEP00000032887 ENSMNEP00000032887 PSMC1 PSMC1 ENSMNEP00000031812 ENSMNEP00000031812 LIN37 LIN37 E2F5 E2F5 LIN9 LIN9 PSMB9 PSMB9 CDC25A CDC25A AKT2 AKT2 PSMD14 PSMD14 PSMB3 PSMB3 ENSMNEP00000027884 ENSMNEP00000027884 RPS27A RPS27A PSMA4 PSMA4 ENSMNEP00000010989 ENSMNEP00000010989 PSMC4 PSMC4 ENSMNEP00000011567 ENSMNEP00000011567 AKT1 AKT1 PSMD2 PSMD2 PSMC5 PSMC5 CCNE2 CCNE2 E2F1 E2F1 ENSMNEP00000005892 ENSMNEP00000005892 ENSMNEP00000005796 ENSMNEP00000005796 E2F4 E2F4 MYC MYC ENSMNEP00000004441 ENSMNEP00000004441 PSMD1 PSMD1 ENSMNEP00000004092 ENSMNEP00000004092 ENSMNEP00000004083 ENSMNEP00000004083 PSMC2 PSMC2 ENSMNEP00000002894 ENSMNEP00000002894 ENSMNEP00000002753 ENSMNEP00000002753 CCNA2 CCNA2 LOC105475719 LOC105475719 PSMA6 PSMA6 PSMD7 PSMD7 CUL1 CUL1 PSMA3 PSMA3 ENSMNEP00000023008 ENSMNEP00000023008 PSMB6 PSMB6 ENSMNEP00000022472 ENSMNEP00000022472 PSMB7 PSMB7 PSMB1 PSMB1 PSMA5 PSMA5 ENSMNEP00000019698 ENSMNEP00000019698 RBL2 RBL2 ENSMNEP00000019162 ENSMNEP00000019162 WEE2 WEE2 PSMD11 PSMD11 SKP1 SKP1 PSMD12 PSMD12 CDK4 CDK4 PSMD3 PSMD3 CKS2 CKS2 ENSMNEP00000015849 ENSMNEP00000015849 CDKN1B CDKN1B MNAT1 MNAT1 PSMD8 PSMD8 MAX MAX PSME2 PSME2 KIAA2012 KIAA2012 ENSMNEP00000012372 ENSMNEP00000012372 PSMD9 PSMD9 RB1 RB1 ENSMNEP00000002323 ENSMNEP00000002323 CDKN1A CDKN1A ENSMNEP00000001974 ENSMNEP00000001974 ENSMNEP00000001266 ENSMNEP00000001266 PSMA1 PSMA1 PSME3 PSME3 ENSMNEP00000000174 ENSMNEP00000000174
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (407 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (333 aa)
ENSMNEP00000007101Uncharacterized protein. (191 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ENSMNEP00000007573MPN domain-containing protein. (149 aa)
PTK6Tyrosine-protein kinase. (397 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
ENSMNEP00000008415Ubiquitin-like domain-containing protein. (83 aa)
CABLES1Cdk5 and Abl enzyme substrate 1. (628 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
ENSMNEP00000008478Ubiquitin-like domain-containing protein. (120 aa)
ENSMNEP00000010116CSN8_PSD8_EIF3K domain-containing protein. (243 aa)
LIN54Lin-54 DREAM MuvB core complex component. (749 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
TFDP1Transcription factor. (410 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
PSMB5Proteasome subunit beta. (263 aa)
LIN52Lin-52 DREAM MuvB core complex component. (116 aa)
ENSMNEP00000042738Uncharacterized protein. (394 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (425 aa)
ENSMNEP00000042381Uncharacterized protein. (312 aa)
ENSMNEP00000042218Uncharacterized protein; Belongs to the SKP1 family. (171 aa)
ENSMNEP00000041258Prot_ATP_ID_OB domain-containing protein. (166 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (403 aa)
PSMB2Proteasome subunit beta. (201 aa)
ENSMNEP00000039425Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSMNEP00000038934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
ENSMNEP00000036869Uncharacterized protein. (97 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
ENSMNEP00000036101Uncharacterized protein. (167 aa)
WEE1Wee1-like protein kinase. (646 aa)
ENSMNEP00000035304Ubiquitin-like domain-containing protein. (134 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (493 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (339 aa)
TFDP2Transcription factor. (447 aa)
ENSMNEP00000032887Protein kinase domain-containing protein. (324 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
ENSMNEP00000031812Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (94 aa)
LIN37Lin-37 DREAM MuvB core complex component. (246 aa)
E2F5E2F transcription factor 5. (346 aa)
LIN9Lin-9 DREAM MuvB core complex component. (558 aa)
PSMB9Proteasome subunit beta. (219 aa)
CDC25ACell division cycle 25A. (524 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSMNEP00000027884PROTEASOME_ALPHA_1 domain-containing protein. (45 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
ENSMNEP00000010989Proteasome endopeptidase complex. (241 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ENSMNEP00000011567Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
E2F1E2F transcription factor 1. (437 aa)
ENSMNEP00000005892Ubiquitin-like domain-containing protein. (156 aa)
ENSMNEP00000005796Ribosomal_S27 domain-containing protein. (137 aa)
E2F4E2F transcription factor 4. (415 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
ENSMNEP0000000444126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa)
ENSMNEP00000004092Proteasome subunit alpha type. (231 aa)
ENSMNEP00000004083Ubiquitin-like domain-containing protein. (127 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa)
ENSMNEP00000002894WD_REPEATS_REGION domain-containing protein. (419 aa)
ENSMNEP00000002753Ubiquitin-like domain-containing protein. (156 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
LOC105475719Ubiquitin-like domain-containing protein. (127 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ENSMNEP00000023008ANK_REP_REGION domain-containing protein. (159 aa)
PSMB6Proteasome subunit beta. (285 aa)
ENSMNEP00000022472AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSMNEP00000019698WD_REPEATS_REGION domain-containing protein. (381 aa)
RBL2RB transcriptional corepressor like 2. (1141 aa)
ENSMNEP00000019162AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
WEE2Wee1-like protein kinase. (568 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (260 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (469 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
ENSMNEP00000015849Transcription factor. (392 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (316 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
MAXMYC associated factor X. (160 aa)
PSME2Proteasome activator subunit 2. (254 aa)
KIAA2012KIAA2012. (1180 aa)
ENSMNEP00000012372WD_REPEATS_REGION domain-containing protein. (406 aa)
PSMD9PDZ domain-containing protein. (223 aa)
RB1RB transcriptional corepressor 1. (928 aa)
ENSMNEP00000002323WD_REPEATS_REGION domain-containing protein. (380 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
ENSMNEP00000001974WD_REPEATS_REGION domain-containing protein. (415 aa)
ENSMNEP00000001266Uncharacterized protein. (234 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
PSME3Proteasome activator subunit 3. (265 aa)
ENSMNEP00000000174AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.