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| | ENSMNEP00000000174 | AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa) |
| | LOC105493523 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1189 aa) |
| | ENSMNEP00000000684 | DOC domain-containing protein. (126 aa) |
| | ENSMNEP00000000708 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (179 aa) |
| | PSME3 | Proteasome activator subunit 3. (265 aa) |
| | MEIOB | Meiosis specific with OB-fold. (476 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | ENSMNEP00000001266 | Uncharacterized protein. (234 aa) |
| | ENSMNEP00000001312 | Uncharacterized protein. (139 aa) |
| | ENSMNEP00000001356 | Uncharacterized protein. (139 aa) |
| | ENSMNEP00000001946 | Uncharacterized protein. (83 aa) |
| | ENSMNEP00000001974 | WD_REPEATS_REGION domain-containing protein. (415 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | ENSMNEP00000002323 | WD_REPEATS_REGION domain-containing protein. (380 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | LOC105475719 | Ubiquitin-like domain-containing protein. (127 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | ENSMNEP00000002753 | Ubiquitin-like domain-containing protein. (156 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (544 aa) |
| | POLD4 | Uncharacterized protein. (107 aa) |
| | ENSMNEP00000002894 | WD_REPEATS_REGION domain-containing protein. (419 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (117 aa) |
| | WAPL | WAPL cohesin release factor. (1190 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa) |
| | ENSMNEP00000004083 | Ubiquitin-like domain-containing protein. (127 aa) |
| | ENSMNEP00000004092 | Proteasome subunit alpha type. (231 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa) |
| | ENSMNEP00000004441 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | CDC16 | Cell division cycle 16. (620 aa) |
| | E2F4 | E2F transcription factor 4. (415 aa) |
| | ENSMNEP00000005796 | Ribosomal_S27 domain-containing protein. (137 aa) |
| | ENSMNEP00000005892 | Ubiquitin-like domain-containing protein. (156 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (407 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1061 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (333 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa) |
| | ENSMNEP00000007101 | Uncharacterized protein. (191 aa) |
| | ENSMNEP00000007239 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (94 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | ENSMNEP00000007573 | MPN domain-containing protein. (149 aa) |
| | PTK6 | Tyrosine-protein kinase. (397 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | PDS5A | PDS5 cohesin associated factor A. (1297 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | ENSMNEP00000008415 | Ubiquitin-like domain-containing protein. (83 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (628 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | ENSMNEP00000008478 | Ubiquitin-like domain-containing protein. (120 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (493 aa) |
| | CDC23 | Cell division cycle 23. (597 aa) |
| | TM4SF19 | Uncharacterized protein. (209 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1233 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (155 aa) |
| | ENSMNEP00000010116 | CSN8_PSD8_EIF3K domain-containing protein. (243 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | ENSMNEP00000010901 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (547 aa) |
| | ENSMNEP00000010989 | Proteasome endopeptidase complex. (241 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | ENSMNEP00000011567 | Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa) |
| | CDC45 | Cell division cycle 45. (598 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (785 aa) |
| | PSME4 | Proteasome activator subunit 4. (1844 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | ENSMNEP00000012372 | WD_REPEATS_REGION domain-containing protein. (406 aa) |
| | RFC5 | Replication factor C subunit 5. (340 aa) |
| | ORC2 | Origin recognition complex subunit 2. (577 aa) |
| | KIAA2012 | KIAA2012. (1180 aa) |
| | STAG1 | Stromal antigen 1. (1258 aa) |
| | ORC3 | Origin recognition complex subunit 3. (712 aa) |
| | LIG1 | DNA ligase. (919 aa) |
| | PSME2 | Proteasome activator subunit 2. (254 aa) |
| | GINS3 | GINS complex subunit 3. (255 aa) |
| | ENSMNEP00000014128 | Uncharacterized protein. (542 aa) |
| | ENSMNEP00000014131 | Uncharacterized protein. (72 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | MAX | MYC associated factor X. (160 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | ENSMNEP00000014814 | Uncharacterized protein. (137 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (316 aa) |
| | ENSMNEP00000015014 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (596 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | ENSMNEP00000015229 | Uncharacterized protein. (572 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | ENSMNEP00000015849 | Transcription factor. (392 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (469 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (260 aa) |
| | POLA1 | DNA polymerase. (1478 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (374 aa) |
| | RFC1 | Replication factor C subunit 1. (1148 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (504 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | WEE2 | Wee1-like protein kinase. (568 aa) |
| | ENSMNEP00000019162 | AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1141 aa) |
| | ENSMNEP00000019698 | WD_REPEATS_REGION domain-containing protein. (381 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | MCM8 | MCM domain-containing protein; Belongs to the MCM family. (863 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | STAG2 | Stromal antigen 2. (1268 aa) |
| | ENSMNEP00000021101 | Zf-rbx1 domain-containing protein. (93 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | RFC2 | Replication factor C subunit 2. (340 aa) |
| | ENSMNEP00000022472 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) |
| | PSMB6 | Proteasome subunit beta. (285 aa) |
| | ENSMNEP00000023008 | ANK_REP_REGION domain-containing protein. (159 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | ENSMNEP00000023094 | Uncharacterized protein. (159 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2263 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | GINS1 | GINS complex subunit 1. (196 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (853 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa) |
| | CDCA5 | Cell division cycle associated 5. (267 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa) |
| | ENSMNEP00000026028 | Uncharacterized protein. (77 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | PSMA4 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (691 aa) |
| | FAM89A | Family with sequence similarity 89 member A. (184 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | ENSMNEP00000027884 | PROTEASOME_ALPHA_1 domain-containing protein. (45 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (570 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CDC25A | Cell division cycle 25A. (524 aa) |
| | ESCO2 | Establishment of sister chromatid cohesion N-acetyltransferase 2. (600 aa) |
| | ANAPC15 | Anaphase promoting complex subunit 15. (190 aa) |
| | RBX1 | RING-type domain-containing protein. (108 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | ANAPC11 | Anaphase promoting complex subunit 11. (177 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (558 aa) |
| | ESCO1 | Establishment of sister chromatid cohesion N-acetyltransferase 1. (810 aa) |
| | E2F5 | E2F transcription factor 5. (346 aa) |
| | RFC4 | Replication factor C subunit 4. (363 aa) |
| | POLD1 | DNA polymerase. (1126 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (246 aa) |
| | UBE2E1 | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | ENSMNEP00000031812 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (94 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | ENSMNEP00000032887 | Protein kinase domain-containing protein. (324 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1828 aa) |
| | TCERG1L | Transcription elongation regulator 1 like. (586 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | TFDP2 | Transcription factor. (447 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (339 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (493 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | ENSMNEP00000035304 | Ubiquitin-like domain-containing protein. (134 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1833 aa) |
| | ENSMNEP00000036101 | Uncharacterized protein. (167 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (545 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | ENSMNEP00000036869 | Uncharacterized protein. (97 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (325 aa) |
| | ENSMNEP00000037405 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (164 aa) |
| | FAM89B | Family with sequence similarity 89 member B. (154 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (742 aa) |
| | ENSMNEP00000038934 | ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (524 aa) |
| | ENSMNEP00000039425 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (403 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (556 aa) |
| | GMNN | Geminin DNA replication inhibitor. (209 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | ANAPC16 | Anaphase promoting complex subunit 16. (110 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | UBE2C | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | ENSMNEP00000041258 | Prot_ATP_ID_OB domain-containing protein. (166 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | PDS5B | PDS5 cohesin associated factor B. (1420 aa) |
| | POLD3 | Uncharacterized protein. (466 aa) |
| | ENSMNEP00000042122 | Uncharacterized protein. (222 aa) |
| | ENSMNEP00000042218 | Uncharacterized protein; Belongs to the SKP1 family. (171 aa) |
| | CDC25B | Cell division cycle 25B. (580 aa) |
| | ENSMNEP00000042381 | Uncharacterized protein. (312 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | ENSMNEP00000042738 | Uncharacterized protein. (394 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (116 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (812 aa) |
| | PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | CDC27 | Cell division cycle 27. (834 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | RAD21 | RAD21 cohesin complex component. (631 aa) |
| | ENSMNEP00000045253 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (234 aa) |
| | SKP2 | S-phase kinase associated protein 2. (424 aa) |
| | RCBTB2 | RCC1 and BTB domain containing protein 2. (556 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | ENSMNEP00000045772 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (578 aa) |
