Your Input: | |||||
PSMB6 | Proteasome subunit beta. (285 aa) | ||||
ENSMNEP00000000174 | AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa) | ||||
TDRD3 | Tudor domain containing 3. (744 aa) | ||||
CCNB1 | Cyclin B1; Belongs to the cyclin family. (433 aa) | ||||
LOC105491644 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
PSME3 | Proteasome activator subunit 3. (265 aa) | ||||
LOC105466836 | Histone domain-containing protein; Belongs to the histone H2B family. (126 aa) | ||||
ENSMNEP00000000889 | annotation not available (103 aa) | ||||
MEIOB | Meiosis specific with OB-fold. (476 aa) | ||||
PSMA1 | Proteasome subunit alpha type. (269 aa) | ||||
H2BC14 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3032 aa) | ||||
ENSMNEP00000001312 | Uncharacterized protein. (139 aa) | ||||
ENSMNEP00000001356 | Uncharacterized protein. (139 aa) | ||||
LOC112422912 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
ENSMNEP00000001463 | annotation not available (103 aa) | ||||
ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) | ||||
H2BU1 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC105478980 | Histone H4. (103 aa) | ||||
LOC105491634 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
H2BC1 | Histone H2B; Belongs to the histone H2B family. (127 aa) | ||||
ENSMNEP00000001946 | Uncharacterized protein. (83 aa) | ||||
ATRIP | ATR interacting protein. (769 aa) | ||||
ENSMNEP00000002194 | annotation not available (103 aa) | ||||
RAD1 | Uncharacterized protein. (280 aa) | ||||
H2BC3 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC105482560 | Histone domain-containing protein; Belongs to the histone H2B family. (127 aa) | ||||
PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) | ||||
PSMA6 | Proteasome subunit alpha type. (246 aa) | ||||
RNF169 | Ring finger protein 169. (709 aa) | ||||
LOC105475719 | Ubiquitin-like domain-containing protein. (127 aa) | ||||
ENSMNEP00000002753 | Ubiquitin-like domain-containing protein. (156 aa) | ||||
H2BC6 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC105497787 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (544 aa) | ||||
HUS1B | Checkpoint protein; Belongs to the HUS1 family. (277 aa) | ||||
LOC105499496 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa) | ||||
H2BC8 | Histone H2B type 1. (126 aa) | ||||
LOC105482579 | Histone H2B type 1. (126 aa) | ||||
ENSMNEP00000003706 | Histone H2B; Belongs to the histone H2B family. (136 aa) | ||||
H2BC11 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
H3-4 | Histone H3; Belongs to the histone H3 family. (136 aa) | ||||
PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa) | ||||
ENSMNEP00000004083 | Ubiquitin-like domain-containing protein. (127 aa) | ||||
ENSMNEP00000004092 | Proteasome subunit alpha type. (231 aa) | ||||
PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa) | ||||
LOC105482573 | Histone H4. (103 aa) | ||||
WDR41 | WD repeat domain 41. (459 aa) | ||||
ENSMNEP00000004441 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa) | ||||
LOC105491665 | Histone H4. (103 aa) | ||||
HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) | ||||
LOC105482579-2 | Histone H2B type 1. (126 aa) | ||||
LOC105482586 | Histone H4. (103 aa) | ||||
ENSMNEP00000004997 | annotation not available (103 aa) | ||||
LOC105499682 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
H2BC5 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
ENSMNEP00000005796 | Ribosomal_S27 domain-containing protein. (137 aa) | ||||
ENSMNEP00000005892 | Ubiquitin-like domain-containing protein. (156 aa) | ||||
CDC7 | Protein kinase domain-containing protein. (574 aa) | ||||
SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) | ||||
ENSMNEP00000006547 | annotation not available (103 aa) | ||||
DNA2 | DNA replication helicase/nuclease 2. (1061 aa) | ||||
PSMA7 | Proteasome subunit alpha type. (248 aa) | ||||
TOPBP1 | DNA topoisomerase II binding protein 1. (1622 aa) | ||||
CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (333 aa) | ||||
YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa) | ||||
ENSMNEP00000007101 | Uncharacterized protein. (191 aa) | ||||
LOC105482587 | Uncharacterized LOC105482587. (103 aa) | ||||
PSME1 | Proteasome activator subunit 1. (249 aa) | ||||
PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) | ||||
ENSMNEP00000007573 | MPN domain-containing protein. (149 aa) | ||||
PSMB10 | Proteasome subunit beta. (273 aa) | ||||
PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) | ||||
ENSMNEP00000008415 | Ubiquitin-like domain-containing protein. (83 aa) | ||||
ENSMNEP00000008478 | Ubiquitin-like domain-containing protein. (120 aa) | ||||
TM4SF19 | Uncharacterized protein. (209 aa) | ||||
ENSMNEP00000009204 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (224 aa) | ||||
ENSMNEP00000009671 | Uncharacterized protein. (80 aa) | ||||
RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (566 aa) | ||||
ENSMNEP00000010116 | CSN8_PSD8_EIF3K domain-containing protein. (243 aa) | ||||
PSMA8 | Proteasome subunit alpha type. (250 aa) | ||||
ENSMNEP00000010901 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (547 aa) | ||||
MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa) | ||||
ENSMNEP00000010989 | Proteasome endopeptidase complex. (241 aa) | ||||
PIAS4 | Protein inhibitor of activated STAT 4. (529 aa) | ||||
PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) | ||||
ENSMNEP00000011567 | Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa) | ||||
CDC45 | Cell division cycle 45. (598 aa) | ||||
MCM6 | DNA helicase; Belongs to the MCM family. (785 aa) | ||||
PSME4 | Proteasome activator subunit 4. (1844 aa) | ||||
PSMD9 | PDZ domain-containing protein. (223 aa) | ||||
ENSMNEP00000012417 | Uncharacterized protein. (235 aa) | ||||
NSD2 | Nuclear receptor binding SET domain protein 2. (1365 aa) | ||||
RFC5 | Replication factor C subunit 5. (340 aa) | ||||
ORC2 | Origin recognition complex subunit 2. (577 aa) | ||||
ENSMNEP00000012828 | Histone H2B; Belongs to the histone H2B family. (129 aa) | ||||
ORC3 | Origin recognition complex subunit 3. (712 aa) | ||||
PSME2 | Proteasome activator subunit 2. (254 aa) | ||||
ENSMNEP00000014131 | Uncharacterized protein. (72 aa) | ||||
BLM | BLM RecQ like helicase. (1375 aa) | ||||
ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) | ||||
ENSMNEP00000014298 | Uncharacterized protein. (202 aa) | ||||
PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) | ||||
LOC105499746 | Histone domain-containing protein; Belongs to the histone H2B family. (175 aa) | ||||
ENSMNEP00000015014 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (596 aa) | ||||
CLSPN | Claspin. (1342 aa) | ||||
RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) | ||||
RMI2 | RecQ mediated genome instability 2. (147 aa) | ||||
PSMD3 | Proteasome 26S subunit, non-ATPase 3. (469 aa) | ||||
ENSMNEP00000016333 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (190 aa) | ||||
EXO1 | Exonuclease 1. (846 aa) | ||||
MCM10 | Minichromosome maintenance 10 replication initiation factor. (877 aa) | ||||
PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) | ||||
PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) | ||||
ENSMNEP00000017193 | Uncharacterized protein. (65 aa) | ||||
WRN | WRN RecQ like helicase. (1432 aa) | ||||
UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) | ||||
ENSMNEP00000017370 | Uncharacterized protein; Belongs to the cyclin family. (341 aa) | ||||
RFC3 | Replication factor C subunit 3. (356 aa) | ||||
WEE2 | Wee1-like protein kinase. (568 aa) | ||||
BRCC3 | MPN domain-containing protein. (297 aa) | ||||
BABAM1 | BRISC and BRCA1 A complex member 1. (254 aa) | ||||
ENSMNEP00000019162 | AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa) | ||||
MCM8 | MCM domain-containing protein; Belongs to the MCM family. (863 aa) | ||||
ENSMNEP00000020290 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (125 aa) | ||||
ENSMNEP00000020581 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (208 aa) | ||||
PSMA5 | Proteasome subunit alpha type. (241 aa) | ||||
RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (486 aa) | ||||
BRCA1 | BRCA1 DNA repair associated. (1894 aa) | ||||
PSMB1 | Proteasome subunit beta. (241 aa) | ||||
ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) | ||||
MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) | ||||
PSMB7 | Proteasome subunit beta. (277 aa) | ||||
RFC2 | Replication factor C subunit 2. (340 aa) | ||||
ENSMNEP00000022472 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) | ||||
ENSMNEP00000022556 | Histone H2B; Belongs to the histone H2B family. (134 aa) | ||||
ENSMNEP00000022738 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (220 aa) | ||||
CCNB3 | Cyclin B3; Belongs to the cyclin family. (1363 aa) | ||||
ENSMNEP00000023008 | ANK_REP_REGION domain-containing protein. (159 aa) | ||||
PSMA3 | Proteasome subunit alpha type. (255 aa) | ||||
UIMC1 | Ubiquitin interaction motif containing 1. (712 aa) | ||||
PIEZO1 | Piezo-type mechanosensitive ion channel component. (2527 aa) | ||||
MCM3 | DNA helicase; Belongs to the MCM family. (853 aa) | ||||
CNTD2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (304 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) | ||||
MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa) | ||||
RAD50 | Zinc-hook domain-containing protein. (1355 aa) | ||||
RAD17 | RAD17 checkpoint clamp loader component. (681 aa) | ||||
YWHAQ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa) | ||||
ENSMNEP00000024827 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (269 aa) | ||||
CDC25C | Cell division cycle 25C. (507 aa) | ||||
RECQL4 | RecQ like helicase 4. (1208 aa) | ||||
PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) | ||||
HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4834 aa) | ||||
PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa) | ||||
ENSMNEP00000026028 | Uncharacterized protein. (77 aa) | ||||
PSMA4 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa) | ||||
H2BC15 | Histone H2B; Belongs to the histone H2B family. (166 aa) | ||||
RPS27A | Ubiquitin-like domain-containing protein. (156 aa) | ||||
PSMB3 | Proteasome subunit beta. (205 aa) | ||||
PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) | ||||
LOC105481870 | Histone H4. (103 aa) | ||||
CDC25A | Cell division cycle 25A. (524 aa) | ||||
LOC105491641 | Uncharacterized LOC105491641. (103 aa) | ||||
ENSMNEP00000029305 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (214 aa) | ||||
DBF4 | DBF4 zinc finger. (675 aa) | ||||
EXD2 | Exonuclease 3'-5' domain containing 2. (620 aa) | ||||
ENSMNEP00000030379 | MPN domain-containing protein. (285 aa) | ||||
PSMB9 | Proteasome subunit beta. (219 aa) | ||||
CCNB2 | Cyclin B2; Belongs to the cyclin family. (391 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (270 aa) | ||||
TP53BP1 | Tumor protein p53 binding protein 1. (1926 aa) | ||||
RFC4 | Replication factor C subunit 4. (363 aa) | ||||
ENSMNEP00000031713 | 14_3_3 domain-containing protein. (92 aa) | ||||
PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) | ||||
YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa) | ||||
ENSMNEP00000033448 | Uncharacterized protein. (231 aa) | ||||
UBE2N | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) | ||||
LOC105466675 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa) | ||||
PSMD13 | Proteasome 26S subunit, non-ATPase 13. (339 aa) | ||||
PSMD5 | Proteasome 26S subunit, non-ATPase 5. (493 aa) | ||||
LOC105486897 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (142 aa) | ||||
BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1217 aa) | ||||
ENSMNEP00000035304 | Ubiquitin-like domain-containing protein. (134 aa) | ||||
WEE1 | Wee1-like protein kinase. (646 aa) | ||||
PIEZO2 | Piezo-type mechanosensitive ion channel component. (2778 aa) | ||||
GTSE1 | G2 and S-phase expressed 1. (739 aa) | ||||
TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (996 aa) | ||||
ENSMNEP00000036101 | Uncharacterized protein. (167 aa) | ||||
ABRAXAS1 | Abraxas 1, BRCA1 A complex subunit. (409 aa) | ||||
PSMF1 | Proteasome inhibitor subunit 1. (271 aa) | ||||
RBBP8 | RB binding protein 8, endonuclease. (867 aa) | ||||
YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (257 aa) | ||||
ENSMNEP00000036686 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (234 aa) | ||||
ENSMNEP00000036869 | Uncharacterized protein. (97 aa) | ||||
ENSMNEP00000037725 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) | ||||
BARD1 | BRCA1 associated RING domain 1. (777 aa) | ||||
ORC5 | Origin recognition complex subunit 5. (435 aa) | ||||
MCM5 | DNA helicase; Belongs to the MCM family. (742 aa) | ||||
ENSMNEP00000038934 | ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa) | ||||
PSMB2 | Proteasome subunit beta. (201 aa) | ||||
PSMD4 | Proteasome 26S subunit, non-ATPase 4. (403 aa) | ||||
ENSMNEP00000039662 | Protein kinase domain-containing protein. (539 aa) | ||||
NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa) | ||||
CHEK2 | Checkpoint kinase 2. (588 aa) | ||||
SLF1 | SMC5-SMC6 complex localization factor 1. (1059 aa) | ||||
YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) | ||||
PSMA2 | Proteasome subunit alpha type. (234 aa) | ||||
MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) | ||||
LOC105491382 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa) | ||||
ORC6 | Origin recognition complex subunit 6. (252 aa) | ||||
RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (420 aa) | ||||
PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) | ||||
ENSMNEP00000041258 | Prot_ATP_ID_OB domain-containing protein. (166 aa) | ||||
LOC105495690 | Uncharacterized protein. (63 aa) | ||||
ENSMNEP00000042381 | Uncharacterized protein. (312 aa) | ||||
CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) | ||||
ENSMNEP00000042738 | Uncharacterized protein. (394 aa) | ||||
RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (417 aa) | ||||
PSMB5 | Proteasome subunit beta. (263 aa) | ||||
LOC105499692 | Histone domain-containing protein; Belongs to the histone H2B family. (175 aa) | ||||
CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) | ||||
PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa) | ||||
RPA3 | Replication protein A3. (121 aa) | ||||
LOC105499748 | Histone domain-containing protein; Belongs to the histone H2B family. (175 aa) | ||||
PSMB8 | Proteasome subunit beta. (276 aa) | ||||
MDC1 | Mediator of DNA damage checkpoint 1. (1965 aa) | ||||
CHEK1 | Checkpoint kinase 1. (493 aa) | ||||
PKMYT1 | Protein kinase, membrane associated tyrosine/threonine 1. (555 aa) | ||||
RCBTB2 | RCC1 and BTB domain containing protein 2. (556 aa) |