STRINGSTRING
ENSMNEP00000002753 ENSMNEP00000002753 ENSMNEP00000000174 ENSMNEP00000000174 PSME3 PSME3 PSMA1 PSMA1 ATM ATM CDKN1A CDKN1A PSMD7 PSMD7 PSMA6 PSMA6 LOC105475719 LOC105475719 CCNA2 CCNA2 PSMC2 PSMC2 ENSMNEP00000004083 ENSMNEP00000004083 ENSMNEP00000004092 ENSMNEP00000004092 PSMD1 PSMD1 ENSMNEP00000004441 ENSMNEP00000004441 ENSMNEP00000005796 ENSMNEP00000005796 ENSMNEP00000005892 ENSMNEP00000005892 MDM4 MDM4 CCNE1 CCNE1 PSMA7 PSMA7 CDK3 CDK3 ENSMNEP00000007101 ENSMNEP00000007101 PSME1 PSME1 PSMD6 PSMD6 ENSMNEP00000007573 ENSMNEP00000007573 PSMB10 PSMB10 PSMB4 PSMB4 PCBP4 PCBP4 ENSMNEP00000008415 ENSMNEP00000008415 CCNA1 CCNA1 ENSMNEP00000008478 ENSMNEP00000008478 ENSMNEP00000010116 ENSMNEP00000010116 PSMA8 PSMA8 ENSMNEP00000010989 ENSMNEP00000010989 PSMC4 PSMC4 ENSMNEP00000011567 ENSMNEP00000011567 PSME4 PSME4 PSMD9 PSMD9 PSME2 PSME2 PSMD8 PSMD8 CDKN1B CDKN1B PSMD3 PSMD3 PSMD12 PSMD12 PSMD11 PSMD11 UBA52 UBA52 ENSMNEP00000019162 ENSMNEP00000019162 ZNF385B ZNF385B PSMA5 PSMA5 PSMB1 PSMB1 PSMB7 PSMB7 PHF20 PHF20 C17orf113 C17orf113 ENSMNEP00000022472 ENSMNEP00000022472 PSMB6 PSMB6 ENSMNEP00000023008 ENSMNEP00000023008 PSMA3 PSMA3 CCNE2 CCNE2 PSMC5 PSMC5 PSMD2 PSMD2 PSMA4 PSMA4 RPS27A RPS27A PSMB3 PSMB3 PSMD14 PSMD14 PSMB9 PSMB9 TP53 TP53 ZNF385A ZNF385A PSMC1 PSMC1 PSMD13 PSMD13 PSMD5 PSMD5 ENSMNEP00000035304 ENSMNEP00000035304 ENSMNEP00000036101 ENSMNEP00000036101 PSMF1 PSMF1 MDM2 MDM2 ENSMNEP00000036869 ENSMNEP00000036869 COP1 COP1 ENSMNEP00000038934 ENSMNEP00000038934 PSMB2 PSMB2 PSMD4 PSMD4 CHEK2 CHEK2 PSMA2 PSMA2 PSMD10 PSMD10 ENSMNEP00000041258 ENSMNEP00000041258 ENSMNEP00000042381 ENSMNEP00000042381 ENSMNEP00000042738 ENSMNEP00000042738 PSMB5 PSMB5 CDK2 CDK2 PSMC3 PSMC3 PSMB8 PSMB8 ZNF385C ZNF385C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000002753Ubiquitin-like domain-containing protein. (156 aa)
ENSMNEP00000000174AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
PSME3Proteasome activator subunit 3. (265 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3032 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
LOC105475719Ubiquitin-like domain-containing protein. (127 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa)
ENSMNEP00000004083Ubiquitin-like domain-containing protein. (127 aa)
ENSMNEP00000004092Proteasome subunit alpha type. (231 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa)
ENSMNEP0000000444126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa)
ENSMNEP00000005796Ribosomal_S27 domain-containing protein. (137 aa)
ENSMNEP00000005892Ubiquitin-like domain-containing protein. (156 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (445 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (407 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (333 aa)
ENSMNEP00000007101Uncharacterized protein. (191 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ENSMNEP00000007573MPN domain-containing protein. (149 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PCBP4Poly(rC) binding protein 4. (406 aa)
ENSMNEP00000008415Ubiquitin-like domain-containing protein. (83 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
ENSMNEP00000008478Ubiquitin-like domain-containing protein. (120 aa)
ENSMNEP00000010116CSN8_PSD8_EIF3K domain-containing protein. (243 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ENSMNEP00000010989Proteasome endopeptidase complex. (241 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ENSMNEP00000011567Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa)
PSME4Proteasome activator subunit 4. (1844 aa)
PSMD9PDZ domain-containing protein. (223 aa)
PSME2Proteasome activator subunit 2. (254 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (469 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ENSMNEP00000019162AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
ZNF385BZinc finger protein 385B. (471 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB7Proteasome subunit beta. (277 aa)
PHF20PHD finger protein 20. (1012 aa)
C17orf113Chromosome 17 open reading frame 113. (675 aa)
ENSMNEP00000022472AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
PSMB6Proteasome subunit beta. (285 aa)
ENSMNEP00000023008ANK_REP_REGION domain-containing protein. (159 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMB9Proteasome subunit beta. (219 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (270 aa)
ZNF385AZinc finger protein 385A. (386 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (339 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (493 aa)
ENSMNEP00000035304Ubiquitin-like domain-containing protein. (134 aa)
ENSMNEP00000036101Uncharacterized protein. (167 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa)
ENSMNEP00000036869Uncharacterized protein. (97 aa)
COP1COP1 E3 ubiquitin ligase. (731 aa)
ENSMNEP00000038934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (403 aa)
CHEK2Checkpoint kinase 2. (588 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSMNEP00000041258Prot_ATP_ID_OB domain-containing protein. (166 aa)
ENSMNEP00000042381Uncharacterized protein. (312 aa)
ENSMNEP00000042738Uncharacterized protein. (394 aa)
PSMB5Proteasome subunit beta. (263 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa)
PSMB8Proteasome subunit beta. (276 aa)
ZNF385CZinc finger protein 385C. (500 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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