51 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NEDD9	Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
	COL1A1	Collagen type I alpha 1 chain. (1464 aa)
	FGG	Fibrinogen gamma chain. (437 aa)
	TLN1	Talin 1. (2556 aa)
	CRK	CRK proto-oncogene, adaptor protein. (304 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1206 aa)
	SHC1	SHC adaptor protein 1. (584 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (610 aa)
	RAP1B	Uncharacterized protein. (137 aa)
	ADRA2C	Adrenoceptor alpha 2C; Belongs to the G-protein coupled receptor 1 family. (368 aa)
	CASS4	Cas scaffold protein family member 4. (732 aa)
	VWF	Von Willebrand factor. (2766 aa)
	ENSMNEP00000039571	Uncharacterized protein. (136 aa)
	GP1BA	Glycoprotein Ib platelet subunit alpha. (613 aa)
	MPL	MPL proto-oncogene, thrombopoietin receptor. (641 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa)
	EFS	Embryonal Fyn-associated substrate. (561 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (582 aa)
	FN1	Fibronectin 1. (2477 aa)
	TLN2	Talin 2. (2544 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (1011 aa)
	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1. (1304 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	COL1A2	Collagen type I alpha 2 chain. (1366 aa)
	THPO	Thrombopoietin. (353 aa)
	APBB1IP	Amyloid beta precursor protein binding family B member 1 interacting protein. (653 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (883 aa)
	RASGRP1	RAS guanyl releasing protein 1. (832 aa)
	RAPGEFL1	Rap guanine nucleotide exchange factor like 1. (662 aa)
	MFSD8	Major facilitator superfamily domain containing 8. (518 aa)
	SRC	Tyrosine-protein kinase. (644 aa)
	RASGRP2	RAS guanyl releasing protein 2. (771 aa)
	ADRA2B	Adrenoceptor alpha 2B. (445 aa)
	GP9	Glycoprotein IX platelet. (177 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (878 aa)
	ADRA2A	Adrenoceptor alpha 2A. (465 aa)
	FGA	Fibrinogen alpha chain. (862 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	LRRC15	Leucine rich repeat containing 15. (584 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa)
	BCAR1	BCAR1 scaffold protein, Cas family member. (916 aa)
	ITGA2B	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
	ENSMNEP00000025369	Uncharacterized protein. (129 aa)
	FGB	Fibrinogen beta chain. (491 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	GP1BB	Glycoprotein Ib platelet subunit beta. (207 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (435 aa)
	SYK	Tyrosine-protein kinase. (629 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1198 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA2A	ADRA2B	ENSMNEP00000001427	ENSMNEP00000004334	Adrenoceptor alpha 2A.	Adrenoceptor alpha 2B.	0.415
ADRA2B	ADRA2A	ENSMNEP00000004334	ENSMNEP00000001427	Adrenoceptor alpha 2B.	Adrenoceptor alpha 2A.	0.415
ADRA2B	ADRA2C	ENSMNEP00000004334	ENSMNEP00000035570	Adrenoceptor alpha 2B.	Adrenoceptor alpha 2C; Belongs to the G-protein coupled receptor 1 family.	0.424
ADRA2C	ADRA2B	ENSMNEP00000035570	ENSMNEP00000004334	Adrenoceptor alpha 2C; Belongs to the G-protein coupled receptor 1 family.	Adrenoceptor alpha 2B.	0.424
AKT1	BCAR1	ENSMNEP00000026038	ENSMNEP00000024739	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCAR1 scaffold protein, Cas family member.	0.426
AKT1	CRK	ENSMNEP00000026038	ENSMNEP00000032388	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CRK proto-oncogene, adaptor protein.	0.457
AKT1	CSK	ENSMNEP00000026038	ENSMNEP00000023214	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.458
AKT1	GRB2	ENSMNEP00000026038	ENSMNEP00000026946	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Growth factor receptor bound protein 2.	0.566
AKT1	PDPK1	ENSMNEP00000026038	ENSMNEP00000045639	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide dependent protein kinase 1.	0.990
AKT1	PTK2	ENSMNEP00000026038	ENSMNEP00000024613	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.558
AKT1	SHC1	ENSMNEP00000026038	ENSMNEP00000034395	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	SHC adaptor protein 1.	0.468
AKT1	SOS1	ENSMNEP00000026038	ENSMNEP00000042754	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.470
AKT1	SRC	ENSMNEP00000026038	ENSMNEP00000006319	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.792
AKT1	TLN1	ENSMNEP00000026038	ENSMNEP00000031542	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Talin 1.	0.425
APBB1IP	BCAR1	ENSMNEP00000010082	ENSMNEP00000024739	Amyloid beta precursor protein binding family B member 1 interacting protein.	BCAR1 scaffold protein, Cas family member.	0.561
APBB1IP	CASS4	ENSMNEP00000010082	ENSMNEP00000036825	Amyloid beta precursor protein binding family B member 1 interacting protein.	Cas scaffold protein family member 4.	0.416
APBB1IP	CRK	ENSMNEP00000010082	ENSMNEP00000032388	Amyloid beta precursor protein binding family B member 1 interacting protein.	CRK proto-oncogene, adaptor protein.	0.634
APBB1IP	CSK	ENSMNEP00000010082	ENSMNEP00000023214	Amyloid beta precursor protein binding family B member 1 interacting protein.	Tyrosine-protein kinase.	0.479
APBB1IP	EFS	ENSMNEP00000010082	ENSMNEP00000045237	Amyloid beta precursor protein binding family B member 1 interacting protein.	Embryonal Fyn-associated substrate.	0.416
APBB1IP	ENSMNEP00000025369	ENSMNEP00000010082	ENSMNEP00000025369	Amyloid beta precursor protein binding family B member 1 interacting protein.	Uncharacterized protein.	0.931