STRINGSTRING
CLP1 CLP1 SYMPK SYMPK FIP1L1 FIP1L1 CSTF1 CSTF1 CPSF7 CPSF7 ENSMNEP00000014519 ENSMNEP00000014519 CPSF2 CPSF2 CPSF4 CPSF4 ENSMNEP00000024434 ENSMNEP00000024434 CPSF6 CPSF6 WDR33 WDR33 NCBP1 NCBP1 NUDT21 NUDT21 PCF11 PCF11 PAPOLA PAPOLA CPSF3 CPSF3 CPSF1 CPSF1 NCBP2 NCBP2 CSTF2 CSTF2 BCL2L2-PABPN1 BCL2L2-PABPN1 CPSF4L CPSF4L CSTF3 CSTF3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
SYMPKSymplekin. (1304 aa)
FIP1L1Fip1 domain-containing protein. (603 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (478 aa)
ENSMNEP00000014519RRM domain-containing protein. (295 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (269 aa)
ENSMNEP00000024434RRM domain-containing protein. (253 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (589 aa)
WDR33WD repeat domain 33. (1336 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
PCF11PCF11 cleavage and polyadenylation factor subunit. (1686 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (625 aa)
CPSF1Cleavage and polyadenylation specific factor 1. (1394 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
CSTF2Cleavage stimulation factor subunit 2. (597 aa)
BCL2L2-PABPN1BCL2L2-PABPN1 readthrough. (333 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (179 aa)
CSTF3Cleavage stimulation factor subunit 3. (717 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.