STRINGSTRING
ENSMNEP00000043788 ENSMNEP00000043788 SKP2 SKP2 HDAC6 HDAC6 RUNX1 RUNX1 PSMB8 PSMB8 PSMC3 PSMC3 LGALS3 LGALS3 PSMB5 PSMB5 ENSMNEP00000042738 ENSMNEP00000042738 CDK1 CDK1 ENSMNEP00000042381 ENSMNEP00000042381 ENSMNEP00000042218 ENSMNEP00000042218 ENSMNEP00000041258 ENSMNEP00000041258 PSMD10 PSMD10 PSMA2 PSMA2 SATB2 SATB2 RUNX2 RUNX2 PSMD4 PSMD4 PSMB2 PSMB2 IHH IHH SOX9 SOX9 AKT3 AKT3 ENSMNEP00000038934 ENSMNEP00000038934 UCMA UCMA ENSMNEP00000036869 ENSMNEP00000036869 PSMF1 PSMF1 DLX6 DLX6 ENSMNEP00000036101 ENSMNEP00000036101 ENSMNEP00000035304 ENSMNEP00000035304 CCND1 CCND1 PSMD5 PSMD5 PSMD13 PSMD13 SOX8 SOX8 PSMC1 PSMC1 ITGBL1 ITGBL1 HAND2 HAND2 PSMB9 PSMB9 COL1A1 COL1A1 ZNF831 ZNF831 RBX1 RBX1 AKT2 AKT2 PSMD14 PSMD14 MMP13 MMP13 PSMB3 PSMB3 NKX3-2 NKX3-2 HEY2 HEY2 RPS27A RPS27A MAF MAF HES1 HES1 ITGA5 ITGA5 BMP2 BMP2 PSMA4 PSMA4 AKT1 AKT1 PSMD2 PSMD2 PSMC5 PSMC5 MSX2 MSX2 CUL1 CUL1 PSMA3 PSMA3 ENSMNEP00000023008 ENSMNEP00000023008 PSMB6 PSMB6 ENSMNEP00000022472 ENSMNEP00000022472 WWP1 WWP1 FBXW7 FBXW7 SP9 SP9 YES1 YES1 SMAD6 SMAD6 PSMB7 PSMB7 PSMB1 PSMB1 ENSMNEP00000021101 ENSMNEP00000021101 PSMA5 PSMA5 PPARGC1B PPARGC1B HEY1 HEY1 SOX30 SOX30 ENSMNEP00000019162 ENSMNEP00000019162 PPM1D PPM1D ESR1 ESR1 HDAC4 HDAC4 NR3C1 NR3C1 STUB1 STUB1 UBA52 UBA52 PSMD11 PSMD11 SKP1 SKP1 PSMD12 PSMD12 CDK4 CDK4 YAP1 YAP1 PSMD3 PSMD3 MAPK3 MAPK3 PSMD8 PSMD8 HES4 HES4 PSME2 PSME2 SMAD4 SMAD4 HDAC3 HDAC3 SMURF1 SMURF1 PSMD9 PSMD9 PSME4 PSME4 RB1 RB1 SP7 SP7 MAPK1 MAPK1 ENSMNEP00000011567 ENSMNEP00000011567 PSMC4 PSMC4 ENSMNEP00000010989 ENSMNEP00000010989 PSMA8 PSMA8 AR AR ENSMNEP00000010116 ENSMNEP00000010116 GLI2 GLI2 WWTR1 WWTR1 CBFB CBFB SP8 SP8 ENSMNEP00000008478 ENSMNEP00000008478 PPARGC1A PPARGC1A PSMB4 PSMB4 PSMB10 PSMB10 ENSMNEP00000007573 ENSMNEP00000007573 PSMD6 PSMD6 ABL1 ABL1 PSME1 PSME1 TWIST2 TWIST2 ENSMNEP00000007101 ENSMNEP00000007101 PSMA7 PSMA7 SRC SRC ESRRA ESRRA SMAD1 SMAD1 ENSMNEP00000005892 ENSMNEP00000005892 ENSMNEP00000005796 ENSMNEP00000005796 ZNF521 ZNF521 HIVEP3 HIVEP3 DLX5 DLX5 ENSMNEP00000004441 ENSMNEP00000004441 GLI3 GLI3 PSMD1 PSMD1 ENSMNEP00000004092 ENSMNEP00000004092 ENSMNEP00000004083 ENSMNEP00000004083 PSMC2 PSMC2 HIVEP1 HIVEP1 RBM14 RBM14 BGLAP BGLAP ENSMNEP00000002753 ENSMNEP00000002753 LOC105475719 LOC105475719 PSMA6 PSMA6 PSMD7 PSMD7 CDKN1A CDKN1A HIVEP2 HIVEP2 ZNF423 ZNF423 PSMA1 PSMA1 STAT1 STAT1 PSME3 PSME3 CCNB1 CCNB1 ENSMNEP00000000174 ENSMNEP00000000174
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000043788NR LBD domain-containing protein. (347 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
HDAC6Histone deacetylase 6. (1183 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa)
LGALS3Galectin. (248 aa)
PSMB5Proteasome subunit beta. (263 aa)
ENSMNEP00000042738Uncharacterized protein. (394 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
ENSMNEP00000042381Uncharacterized protein. (312 aa)
ENSMNEP00000042218Uncharacterized protein; Belongs to the SKP1 family. (171 aa)
ENSMNEP00000041258Prot_ATP_ID_OB domain-containing protein. (166 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
SATB2DNA-binding protein SATB. (733 aa)
RUNX2RUNX family transcription factor 2. (542 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (403 aa)
PSMB2Proteasome subunit beta. (201 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
SOX9SRY-box transcription factor 9. (509 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSMNEP00000038934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
UCMAUpper zone of growth plate and cartilage matrix associated. (138 aa)
ENSMNEP00000036869Uncharacterized protein. (97 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
DLX6Distal-less homeobox 6. (292 aa)
ENSMNEP00000036101Uncharacterized protein. (167 aa)
ENSMNEP00000035304Ubiquitin-like domain-containing protein. (134 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (493 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (339 aa)
SOX8SRY-box transcription factor 8. (361 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
ITGBL1Integrin subunit beta like 1. (494 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
PSMB9Proteasome subunit beta. (219 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
ZNF831Zinc finger protein 831. (1663 aa)
RBX1RING-type domain-containing protein. (108 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
MMP13Matrix metallopeptidase 13. (503 aa)
PSMB3Proteasome subunit beta. (205 aa)
NKX3-2NK3 homeobox 2. (333 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (340 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
MSX2Msh homeobox 2. (267 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ENSMNEP00000023008ANK_REP_REGION domain-containing protein. (159 aa)
PSMB6Proteasome subunit beta. (285 aa)
ENSMNEP00000022472AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
WWP1E3 ubiquitin-protein ligase. (865 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
SP9Sp9 transcription factor. (485 aa)
YES1Tyrosine-protein kinase. (548 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMB1Proteasome subunit beta. (241 aa)
ENSMNEP00000021101Zf-rbx1 domain-containing protein. (93 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PPARGC1BPPARG coactivator 1 beta. (1023 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
SOX30SRY-box transcription factor 30. (753 aa)
ENSMNEP00000019162AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
PPM1DProtein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1094 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (777 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (260 aa)
YAP1Yes associated protein 1. (506 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (469 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
PSME2Proteasome activator subunit 2. (254 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
SMURF1SMAD specific E3 ubiquitin protein ligase 1. (641 aa)
PSMD9PDZ domain-containing protein. (223 aa)
PSME4Proteasome activator subunit 4. (1844 aa)
RB1RB transcriptional corepressor 1. (928 aa)
SP7Sp7 transcription factor. (431 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
ENSMNEP00000011567Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ENSMNEP00000010989Proteasome endopeptidase complex. (241 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ARAndrogen receptor. (898 aa)
ENSMNEP00000010116CSN8_PSD8_EIF3K domain-containing protein. (243 aa)
GLI2GLI family zinc finger 2. (1586 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
CBFBCore-binding factor subunit beta. (182 aa)
SP8Sp8 transcription factor. (507 aa)
ENSMNEP00000008478Ubiquitin-like domain-containing protein. (120 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMB10Proteasome subunit beta. (273 aa)
ENSMNEP00000007573MPN domain-containing protein. (149 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
PSME1Proteasome activator subunit 1. (249 aa)
TWIST2Twist family bHLH transcription factor 2. (160 aa)
ENSMNEP00000007101Uncharacterized protein. (191 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
SRCTyrosine-protein kinase. (644 aa)
ESRRAEstrogen related receptor alpha. (422 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ENSMNEP00000005892Ubiquitin-like domain-containing protein. (156 aa)
ENSMNEP00000005796Ribosomal_S27 domain-containing protein. (137 aa)
ZNF521Zinc finger protein 521. (1311 aa)
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3. (2406 aa)
DLX5Distal-less homeobox 5. (289 aa)
ENSMNEP0000000444126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa)
GLI3GLI family zinc finger 3. (1580 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa)
ENSMNEP00000004092Proteasome subunit alpha type. (231 aa)
ENSMNEP00000004083Ubiquitin-like domain-containing protein. (127 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa)
HIVEP1Human immunodeficiency virus type I enhancer binding protein 1. (2718 aa)
RBM14RNA binding motif protein 14. (669 aa)
BGLAPOsteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium (By similarity). (100 aa)
ENSMNEP00000002753Ubiquitin-like domain-containing protein. (156 aa)
LOC105475719Ubiquitin-like domain-containing protein. (127 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
HIVEP2Human immunodeficiency virus type I enhancer binding protein 2. (2446 aa)
ZNF423Zinc finger protein 423. (1441 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
PSME3Proteasome activator subunit 3. (265 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
ENSMNEP00000000174AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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