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UPP1 UPP1 TYMP TYMP APRT APRT ADK ADK AMPD3 AMPD3 PUDP PUDP GMPR GMPR AMPD1 AMPD1 UPP2 UPP2 UCK2 UCK2 GMPR2 GMPR2 DGUOK DGUOK AMPD2 AMPD2 TK1 TK1 UCK1 UCK1 HPRT1 HPRT1 CDA CDA TK2 TK2 ENSMNEP00000017906 ENSMNEP00000017906 ADA ADA ENKUR ENKUR PNP PNP DCK DCK PRTFDC1 PRTFDC1 UCKL1 UCKL1 ADAL ADAL
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (314 aa)
TYMPThymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (482 aa)
APRTAdenine phosphoribosyltransferase. (180 aa)
ADKAdenosine kinase. (362 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (784 aa)
PUDPPseudouridine 5'-phosphatase. (229 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (747 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (363 aa)
UCK2Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (351 aa)
DGUOKDeoxyguanosine kinase. (277 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (879 aa)
TK1Thymidine kinase. (261 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (277 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (220 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
TK2Thymidine kinase 2. (281 aa)
ENSMNEP00000017906Uncharacterized protein. (187 aa)
ADAAdenosine deaminase. (449 aa)
ENKUREnkurin, TRPC channel interacting protein. (256 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
DCKDeoxycytidine kinase. (317 aa)
PRTFDC1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (220 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (555 aa)
ADALAdenosine deaminase like. (355 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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