STRINGSTRING
ENSMNEP00000002753 ENSMNEP00000002753 ENSMNEP00000004092 ENSMNEP00000004092 PSMD1 PSMD1 ENSMNEP00000004441 ENSMNEP00000004441 SNW1 SNW1 ENSMNEP00000005796 ENSMNEP00000005796 ENSMNEP00000005892 ENSMNEP00000005892 KAT2B KAT2B PSMA7 PSMA7 ENSMNEP00000007101 ENSMNEP00000007101 PSME1 PSME1 PSMB8 PSMB8 PSMC3 PSMC3 PSMB5 PSMB5 ENSMNEP00000042738 ENSMNEP00000042738 ENSMNEP00000042381 ENSMNEP00000042381 ENSMNEP00000042218 ENSMNEP00000042218 HES5 HES5 ENSMNEP00000041258 ENSMNEP00000041258 PSMD10 PSMD10 CREBBP CREBBP EP300 EP300 NCSTN NCSTN PSMA2 PSMA2 CRB1 CRB1 PSMD4 PSMD4 PSMB2 PSMB2 MAML2 MAML2 ENSMNEP00000038934 ENSMNEP00000038934 ENSMNEP00000036869 ENSMNEP00000036869 YWHAZ YWHAZ PSMF1 PSMF1 ENSMNEP00000036101 ENSMNEP00000036101 ADAM10 ADAM10 TACC3 TACC3 ENSMNEP00000035304 ENSMNEP00000035304 PSMD5 PSMD5 NOTCH4 NOTCH4 PSMD13 PSMD13 PSMC1 PSMC1 DLL4 DLL4 PSMB9 PSMB9 PSENEN PSENEN RBX1 RBX1 JAG1 JAG1 ENSMNEP00000029305 ENSMNEP00000029305 RBPJ RBPJ PSMD6 PSMD6 ENSMNEP00000007573 ENSMNEP00000007573 PSMB10 PSMB10 PSMB4 PSMB4 NOTCH2 NOTCH2 ENSMNEP00000009204 ENSMNEP00000009204 ENSMNEP00000010116 ENSMNEP00000010116 ENSMNEP00000010989 ENSMNEP00000010989 PSMC4 PSMC4 ENSMNEP00000011567 ENSMNEP00000011567 PSMD9 PSMD9 FLT4 FLT4 MAMLD1 MAMLD1 NOTCH1 NOTCH1 PSME2 PSME2 HES4 HES4 PSMD8 PSMD8 MAML1 MAML1 PSMD3 PSMD3 PSMD12 PSMD12 SKP1 SKP1 PSMD11 PSMD11 UBA52 UBA52 SMAD3 SMAD3 ENSMNEP00000019162 ENSMNEP00000019162 HEY1 HEY1 PSMA5 PSMA5 APH1A APH1A ENSMNEP00000021101 ENSMNEP00000021101 PSMB1 PSMB1 PSMB7 PSMB7 APH1B APH1B FBXW7 FBXW7 ENSMNEP00000022472 ENSMNEP00000022472 ENSMNEP00000022738 ENSMNEP00000022738 PSMB6 PSMB6 ENSMNEP00000023008 ENSMNEP00000023008 PSMA3 PSMA3 CUL1 CUL1 KAT2A KAT2A PSEN2 PSEN2 PSMC5 PSMC5 PSMD2 PSMD2 AKT1 AKT1 PSMA4 PSMA4 HES1 HES1 RPS27A RPS27A PSEN1 PSEN1 HEY2 HEY2 PSMB3 PSMB3 PSMD14 PSMD14 PSMC2 PSMC2 PSMA6 PSMA6 PSMD7 PSMD7 PSMA1 PSMA1 PSME3 PSME3 ENSMNEP00000000174 ENSMNEP00000000174
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000002753Ubiquitin-like domain-containing protein. (156 aa)
ENSMNEP00000004092Proteasome subunit alpha type. (231 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa)
ENSMNEP0000000444126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa)
SNW1SNW domain containing 1. (571 aa)
ENSMNEP00000005796Ribosomal_S27 domain-containing protein. (137 aa)
ENSMNEP00000005892Ubiquitin-like domain-containing protein. (156 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (800 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
ENSMNEP00000007101Uncharacterized protein. (191 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa)
PSMB5Proteasome subunit beta. (263 aa)
ENSMNEP00000042738Uncharacterized protein. (394 aa)
ENSMNEP00000042381Uncharacterized protein. (312 aa)
ENSMNEP00000042218Uncharacterized protein; Belongs to the SKP1 family. (171 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
ENSMNEP00000041258Prot_ATP_ID_OB domain-containing protein. (166 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
CREBBPCREB binding protein. (2442 aa)
EP300E1A binding protein p300. (2397 aa)
NCSTNNicastrin. (721 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (403 aa)
PSMB2Proteasome subunit beta. (201 aa)
MAML2Mastermind like transcriptional coactivator 2. (1152 aa)
ENSMNEP00000038934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
ENSMNEP00000036869Uncharacterized protein. (97 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (257 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
ENSMNEP00000036101Uncharacterized protein. (167 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (817 aa)
ENSMNEP00000035304Ubiquitin-like domain-containing protein. (134 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (493 aa)
NOTCH4Notch receptor 4. (2001 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (339 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
RBX1RING-type domain-containing protein. (108 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
ENSMNEP0000002930514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (214 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ENSMNEP00000007573MPN domain-containing protein. (149 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
NOTCH2Notch receptor 2. (2471 aa)
ENSMNEP0000000920414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (224 aa)
ENSMNEP00000010116CSN8_PSD8_EIF3K domain-containing protein. (243 aa)
ENSMNEP00000010989Proteasome endopeptidase complex. (241 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ENSMNEP00000011567Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa)
PSMD9PDZ domain-containing protein. (223 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1391 aa)
MAMLD1Mastermind like domain containing 1. (1008 aa)
NOTCH1Notch receptor 1. (2556 aa)
PSME2Proteasome activator subunit 2. (254 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
MAML1Mastermind like transcriptional coactivator 1. (969 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (469 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ENSMNEP00000019162AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
ENSMNEP00000021101Zf-rbx1 domain-containing protein. (93 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB7Proteasome subunit beta. (277 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
ENSMNEP00000022472AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
ENSMNEP0000002273814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (220 aa)
PSMB6Proteasome subunit beta. (285 aa)
ENSMNEP00000023008ANK_REP_REGION domain-containing protein. (159 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
PSME3Proteasome activator subunit 3. (265 aa)
ENSMNEP00000000174AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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