STRINGSTRING
UBA52 UBA52 IKBKG IKBKG PSME3 PSME3 PSMA1 PSMA1 PSMD7 PSMD7 PSMA6 PSMA6 LOC105475719 LOC105475719 ENSMNEP00000002753 ENSMNEP00000002753 LOC105499496 LOC105499496 TAB2 TAB2 TIFA TIFA PSMC2 PSMC2 ENSMNEP00000004083 ENSMNEP00000004083 ENSMNEP00000004092 ENSMNEP00000004092 PSMD1 PSMD1 ENSMNEP00000004441 ENSMNEP00000004441 TRAF2 TRAF2 IRAK2 IRAK2 IRAK1 IRAK1 SQSTM1 SQSTM1 CCDC71L CCDC71L ENSMNEP00000005796 ENSMNEP00000005796 ENSMNEP00000005892 ENSMNEP00000005892 MAP2K1 MAP2K1 PSMA7 PSMA7 ENSMNEP00000007101 ENSMNEP00000007101 PSME1 PSME1 PSMD6 PSMD6 ENSMNEP00000007573 ENSMNEP00000007573 PSMB10 PSMB10 PSMB4 PSMB4 LRRC45 LRRC45 ENSMNEP00000008415 ENSMNEP00000008415 ENSMNEP00000008478 ENSMNEP00000008478 HMGB1 HMGB1 ENSMNEP00000010116 ENSMNEP00000010116 IL1R1 IL1R1 NLRP6 NLRP6 ENSMNEP00000010344 ENSMNEP00000010344 PSMA8 PSMA8 PELI3 PELI3 NFKB1 NFKB1 ENSMNEP00000010989 ENSMNEP00000010989 PSMC4 PSMC4 ENSMNEP00000011567 ENSMNEP00000011567 ENSMNEP00000011718 ENSMNEP00000011718 NFKB2 NFKB2 ENSMNEP00000012002 ENSMNEP00000012002 PSME4 PSME4 PSMD9 PSMD9 PELI1 PELI1 CHUK CHUK PSME2 PSME2 ENSMNEP00000013739 ENSMNEP00000013739 PSMD8 PSMD8 LRRC74A LRRC74A ENSMNEP00000015875 ENSMNEP00000015875 PSMD3 PSMD3 PSMD12 PSMD12 SKP1 SKP1 PSMD11 PSMD11 NOD2 NOD2 LRRC14 LRRC14 MAP3K8 MAP3K8 IRAK3 IRAK3 NKIRAS1 NKIRAS1 AGER AGER ENSMNEP00000019162 ENSMNEP00000019162 FBXW11 FBXW11 PSMA5 PSMA5 ENSMNEP00000021101 ENSMNEP00000021101 PSMB1 PSMB1 PSMB7 PSMB7 TOLLIP TOLLIP S100B S100B ENSMNEP00000022385 ENSMNEP00000022385 ENSMNEP00000022472 ENSMNEP00000022472 NLRP9 NLRP9 PSMB6 PSMB6 PELI2 PELI2 ENSMNEP00000023008 ENSMNEP00000023008 PSMA3 PSMA3 CUL1 CUL1 N4BP1 N4BP1 ALPK1 ALPK1 MAP2K4 MAP2K4 IL1R2 IL1R2 VWC2 VWC2 TONSL TONSL PSMC5 PSMC5 NLRC5 NLRC5 PSMD2 PSMD2 PSMA4 PSMA4 MAP2K6 MAP2K6 NOD1 NOD1 IL1RAP IL1RAP RPS27A RPS27A ENSMNEP00000027902 ENSMNEP00000027902 PSMB3 PSMB3 MAP3K3 MAP3K3 RELA RELA PSMD14 PSMD14 RBX1 RBX1 NKIRAS2 NKIRAS2 TAB3 TAB3 PSMB9 PSMB9 MYD88 MYD88 ENSMNEP00000038934 ENSMNEP00000038934 TAB1 TAB1 PSMB2 PSMB2 PSMD4 PSMD4 PSMA2 PSMA2 LOC105491382 LOC105491382 ENSMNEP00000041120 ENSMNEP00000041120 PSMD10 PSMD10 ENSMNEP00000041258 ENSMNEP00000041258 USP14 USP14 ENSMNEP00000042218 ENSMNEP00000042218 LOC105466675 LOC105466675 IL1A IL1A UBE2N UBE2N IKBKB IKBKB IL1B IL1B IRAK4 IRAK4 MAP3K2 MAP3K2 CASP8 CASP8 PSMC1 PSMC1 LRRC71 LRRC71 NFKBIA NFKBIA LRRC34 LRRC34 MAP3K7 MAP3K7 ENSMNEP00000042381 ENSMNEP00000042381 BTRC BTRC ENSMNEP00000042738 ENSMNEP00000042738 PSMB5 PSMB5 IL1RN IL1RN TRAF6 TRAF6 PSMD13 PSMD13 LRRC31 LRRC31 PSMD5 PSMD5 NLRX1 NLRX1 ENSMNEP00000034709 ENSMNEP00000034709 PSMC3 PSMC3 NFKBIB NFKBIB MAP3K20 MAP3K20 PSMB8 PSMB8 KHNYN KHNYN TNIP2 TNIP2 S100A12 S100A12 APP APP RIPK2 RIPK2 LOC105486978 LOC105486978 ENSMNEP00000037725 ENSMNEP00000037725 ENSMNEP00000036869 ENSMNEP00000036869 ENSMNEP00000036583 ENSMNEP00000036583 PSMF1 PSMF1 NLRP13 NLRP13 ENSMNEP00000036101 ENSMNEP00000036101 ENSMNEP00000035304 ENSMNEP00000035304 MFSD1 MFSD1 ENSMNEP00000000174 ENSMNEP00000000174
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa)
PSME3Proteasome activator subunit 3. (265 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
LOC105475719Ubiquitin-like domain-containing protein. (127 aa)
ENSMNEP00000002753Ubiquitin-like domain-containing protein. (156 aa)
LOC105499496UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
TIFATRAF interacting protein with forkhead associated domain. (185 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa)
ENSMNEP00000004083Ubiquitin-like domain-containing protein. (127 aa)
ENSMNEP00000004092Proteasome subunit alpha type. (231 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa)
ENSMNEP0000000444126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (532 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (625 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (717 aa)
SQSTM1Sequestosome 1. (440 aa)
CCDC71LCoiled-coil domain containing 71 like. (235 aa)
ENSMNEP00000005796Ribosomal_S27 domain-containing protein. (137 aa)
ENSMNEP00000005892Ubiquitin-like domain-containing protein. (156 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (361 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
ENSMNEP00000007101Uncharacterized protein. (191 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ENSMNEP00000007573MPN domain-containing protein. (149 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
ENSMNEP00000008415Ubiquitin-like domain-containing protein. (83 aa)
ENSMNEP00000008478Ubiquitin-like domain-containing protein. (120 aa)
HMGB1High mobility group box 1. (215 aa)
ENSMNEP00000010116CSN8_PSD8_EIF3K domain-containing protein. (243 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
NLRP6NLR family pyrin domain containing 6. (1044 aa)
ENSMNEP00000010344Uncharacterized protein. (206 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
ENSMNEP00000010989Proteasome endopeptidase complex. (241 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ENSMNEP00000011567Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa)
ENSMNEP00000011718Uncharacterized protein. (188 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
ENSMNEP00000012002TNF receptor-associated factor. (457 aa)
PSME4Proteasome activator subunit 4. (1844 aa)
PSMD9PDZ domain-containing protein. (223 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
PSME2Proteasome activator subunit 2. (254 aa)
ENSMNEP00000013739Uncharacterized protein. (202 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
LRRC74ALeucine rich repeat containing 74A. (488 aa)
ENSMNEP00000015875CCHC NOA-type domain-containing protein. (361 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (469 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1044 aa)
LRRC14Leucine rich repeat containing 14. (493 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (572 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (596 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (192 aa)
AGERAdvanced glycosylation end-product specific receptor. (414 aa)
ENSMNEP00000019162AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSMNEP00000021101Zf-rbx1 domain-containing protein. (93 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB7Proteasome subunit beta. (277 aa)
TOLLIPToll interacting protein. (274 aa)
S100BS_100 domain-containing protein; Belongs to the S-100 family. (94 aa)
ENSMNEP00000022385Uncharacterized protein. (64 aa)
ENSMNEP00000022472AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
NLRP9NLR family pyrin domain containing 9. (881 aa)
PSMB6Proteasome subunit beta. (285 aa)
PELI2E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa)
ENSMNEP00000023008ANK_REP_REGION domain-containing protein. (159 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
N4BP1NEDD4 binding protein 1. (896 aa)
ALPK1Alpha kinase 1. (1245 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (374 aa)
IL1R2Interleukin 1 receptor type 2. (398 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
TONSLTonsoku like, DNA repair protein. (1375 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
NLRC5NLR family CARD domain containing 5. (1866 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSMNEP00000027902Protein kinase domain-containing protein. (365 aa)
PSMB3Proteasome subunit beta. (205 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
RBX1RING-type domain-containing protein. (108 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (228 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
PSMB9Proteasome subunit beta. (219 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
ENSMNEP00000038934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (403 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
LOC105491382UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
ENSMNEP00000041120Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSMNEP00000041258Prot_ATP_ID_OB domain-containing protein. (166 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa)
ENSMNEP00000042218Uncharacterized protein; Belongs to the SKP1 family. (171 aa)
LOC105466675UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (224 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (620 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (487 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
LRRC71Leucine rich repeat containing 71. (559 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
LRRC34Leucine rich repeat containing 34. (389 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ENSMNEP00000042381Uncharacterized protein. (312 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
ENSMNEP00000042738Uncharacterized protein. (394 aa)
PSMB5Proteasome subunit beta. (263 aa)
IL1RNInterleukin-1. (179 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (339 aa)
LRRC31Leucine rich repeat containing 31. (552 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (493 aa)
NLRX1NLR family member X1. (972 aa)
ENSMNEP00000034709Uncharacterized protein. (439 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa)
NFKBIBNFKB inhibitor beta. (356 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (908 aa)
PSMB8Proteasome subunit beta. (276 aa)
KHNYNKH and NYN domain containing. (678 aa)
TNIP2TNFAIP3 interacting protein 2. (429 aa)
S100A12S100 calcium binding protein A12. (81 aa)
APPAmyloid beta precursor protein. (770 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
LOC105486978Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
ENSMNEP00000037725UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
ENSMNEP00000036869Uncharacterized protein. (97 aa)
ENSMNEP00000036583Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
NLRP13NLR family pyrin domain containing 13. (1030 aa)
ENSMNEP00000036101Uncharacterized protein. (167 aa)
ENSMNEP00000035304Ubiquitin-like domain-containing protein. (134 aa)
MFSD1Major facilitator superfamily domain containing 1. (514 aa)
ENSMNEP00000000174AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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