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| | BTK | Tyrosine-protein kinase. (659 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | LOC105477893 | Uncharacterized protein. (1747 aa) |
| | MEFV | MEFV innate immuity regulator, pyrin. (786 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | ENSMNEP00000028540 | Uncharacterized protein. (139 aa) |
| | SYK | Tyrosine-protein kinase. (629 aa) |
| | ENSMNEP00000029022 | Uncharacterized protein. (185 aa) |
| | ACTL7A | Actin like 7A; Belongs to the actin family. (435 aa) |
| | ACTRT2 | Actin related protein T2; Belongs to the actin family. (377 aa) |
| | GNAI1 | G protein subunit alpha i1. (422 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | ENSMNEP00000026694 | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (353 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa) |
| | NOXA1 | NADPH oxidase activator 1. (476 aa) |
| | WASL | WASP like actin nucleation promoting factor. (505 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (878 aa) |
| | GNAI3 | G protein subunit alpha i3. (328 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | ENSMNEP00000030807 | Uncharacterized protein. (120 aa) |
| | CD3G | CD3g molecule. (209 aa) |
| | C3 | Complement C3. (1642 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | PRKAR2B | Protein kinase cAMP-dependent type II regulatory subunit beta. (421 aa) |
| | RHBDF1 | Rhomboid 5 homolog 1. (859 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | DPEP1 | Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (411 aa) |
| | ENSMNEP00000032949 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (164 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (224 aa) |
| | CYBA | Cytochrome b-245 alpha chain. (197 aa) |
| | ENTPD5 | Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (427 aa) |
| | GNB5 | G protein subunit beta 5. (409 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | CD247 | CD247 molecule. (164 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (690 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | BAIAP2 | BAI1 associated protein 2. (552 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) |
| | ADCY4 | Adenylate cyclase 4. (1299 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | HCK | Tyrosine-protein kinase. (504 aa) |
| | ENSMNEP00000038155 | Uncharacterized protein. (314 aa) |
| | ENSMNEP00000038177 | Uncharacterized protein; Belongs to the actin family. (156 aa) |
| | GNG13 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa) |
| | ABI1 | Abl interactor 1. (508 aa) |
| | BRK1 | BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa) |
| | GNAZ | G protein subunit alpha z. (355 aa) |
| | LOC105497411 | Uncharacterized protein. (225 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | TXNIP | Thioredoxin interacting protein. (391 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | SCART1 | Scavenger receptor family member expressed on T cells 1. (1006 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (489 aa) |
| | ENSMNEP00000041206 | Uncharacterized protein; Belongs to the actin family. (163 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1214 aa) |
| | ENSMNEP00000041446 | Uncharacterized protein. (60 aa) |
| | FGR | Tyrosine-protein kinase. (529 aa) |
| | ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | PRKAR1A | Uncharacterized protein. (381 aa) |
| | MYO10 | Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2019 aa) |
| | CYSLTR2 | Cysteinyl leukotriene receptor 2. (332 aa) |
| | ACTR2 | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | TXN | Thioredoxin; Belongs to the thioredoxin family. (105 aa) |
| | ENSMNEP00000043922 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (133 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | MYO9B | Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2135 aa) |
| | ENSMNEP00000045127 | Uncharacterized protein. (183 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa) |
| | FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa) |
| | CDC42 | Uncharacterized protein. (191 aa) |
| | HSP90AB1 | Heat shock protein 90 alpha family class B member 1. (724 aa) |
| | WAS | WASP actin nucleation promoting factor. (545 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | ACTB | Actin beta. (379 aa) |
| | CTSG | Cathepsin G; Belongs to the peptidase S1 family. (255 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (846 aa) |
| | FCGR1A | Uncharacterized protein. (357 aa) |
| | WASF2 | WASP family member 2. (499 aa) |
| | ARPC1B | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (375 aa) |
| | DPEP3 | Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (513 aa) |
| | ARPC5 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa) |
| | GGT5 | Gamma-glutamyltransferase 5. (586 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | ENSMNEP00000015467 | Uncharacterized protein. (312 aa) |
| | DPEP2 | Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (490 aa) |
| | ENSMNEP00000014831 | HATPase_c domain-containing protein. (645 aa) |
| | GNAT3 | G protein subunit alpha transducin 3. (354 aa) |
| | CD163 | CD163 molecule. (1155 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | GSDMD | Gasdermin D. (523 aa) |
| | MYO1C | Myosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (968 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (803 aa) |
| | ENSMNEP00000013158 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (718 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1134 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (900 aa) |
| | WIPF2 | WAS/WASL interacting protein family member 2. (246 aa) |
| | ENSMNEP00000011554 | Uncharacterized protein. (157 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa) |
| | NCKAP1 | NCK associated protein 1. (1134 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (968 aa) |
| | PRKAR2A | Protein kinase cAMP-dependent type II regulatory subunit alpha. (359 aa) |
| | PSTPIP1 | Proline-serine-threonine phosphatase interacting protein 1. (416 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa) |
| | GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | RHBDF2 | Rhomboid 5 homolog 2. (836 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | WASF1 | WASP family member 1. (559 aa) |
| | NT5E | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa) |
| | SUGT1 | SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (365 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (875 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | ENSMNEP00000009016 | Uncharacterized protein. (345 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1088 aa) |
| | WASF3 | WASP family member 3. (502 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (517 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | WIPF3 | WAS/WASL interacting protein family member 3. (500 aa) |
| | ABL1 | Tyrosine-protein kinase. (1148 aa) |
| | MYH9 | Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (685 aa) |
| | ENSMNEP00000006433 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa) |
| | SRC | Tyrosine-protein kinase. (644 aa) |
| | MYO5A | Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1756 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | ENSMNEP00000005141 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | ENSMNEP00000004647 | Uncharacterized protein. (185 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa) |
| | ACTRT1 | Actin related protein T1; Belongs to the actin family. (375 aa) |
| | NCKIPSD | NCK interacting protein with SH3 domain. (722 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | CYSLTR1 | Cysteinyl leukotriene receptor 1. (337 aa) |
| | ACTL7B | Actin like 7B; Belongs to the actin family. (415 aa) |
| | ENSMNEP00000002738 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | ACTR3 | Actin related protein 3; Belongs to the actin family. (418 aa) |
| | ACTG1 | Actin gamma 1. (377 aa) |
| | PRKX | Protein kinase X-linked; Belongs to the protein kinase superfamily. (358 aa) |
| | ELMO1 | Engulfment and cell motility 1. (727 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (442 aa) |
| | IL6 | Interleukin 6. (214 aa) |
| | GNAS | GNAS complex locus. (1007 aa) |
| | ELMO2 | Engulfment and cell motility 2. (720 aa) |
| | DOCK1 | Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa) |
| | YES1 | Tyrosine-protein kinase. (548 aa) |
| | AHCYL1 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa) |
| | GGT1 | Uncharacterized protein. (569 aa) |
| | ARPC2 | Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa) |
| | ENSMNEP00000023757 | Uncharacterized protein. (369 aa) |
| | PRKAR1B | Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa) |
| | NOX1 | NADPH oxidase 1. (564 aa) |
| | ARPC4 | Uncharacterized protein. (78 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | ARPC1A | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa) |
| | LOC105493689 | Uncharacterized protein; Belongs to the peptidase C14A family. (410 aa) |
| | APP | Amyloid beta precursor protein. (770 aa) |
| | WIPF1 | WAS/WASL interacting protein family member 1. (510 aa) |
