STRINGSTRING
ENSMNEP00000006433 ENSMNEP00000006433 WIPF1 WIPF1 ARPC1A ARPC1A ARPC4 ARPC4 ARPC5 ARPC5 ENSMNEP00000045127 ENSMNEP00000045127 MYO9B MYO9B ENSMNEP00000043922 ENSMNEP00000043922 ACTR2 ACTR2 MYO10 MYO10 FGR FGR ENSMNEP00000041446 ENSMNEP00000041446 ENSMNEP00000041206 ENSMNEP00000041206 BRK1 BRK1 ABI1 ABI1 ENSMNEP00000038177 ENSMNEP00000038177 HCK HCK LYN LYN BAIAP2 BAIAP2 CD247 CD247 CYFIP2 CYFIP2 ENSMNEP00000032949 ENSMNEP00000032949 CRK CRK CD3G CD3G ENSMNEP00000030807 ENSMNEP00000030807 ACTRT2 ACTRT2 ACTL7A ACTL7A ENSMNEP00000029022 ENSMNEP00000029022 SYK SYK ENSMNEP00000028540 ENSMNEP00000028540 BTK BTK GRB2 GRB2 ENSMNEP00000026694 ENSMNEP00000026694 NCK1 NCK1 PTK2 PTK2 VAV2 VAV2 WASL WASL ARPC2 ARPC2 YES1 YES1 DOCK1 DOCK1 ELMO2 ELMO2 CDC42 CDC42 WAS WAS ACTB ACTB VAV1 VAV1 WASF2 WASF2 ARPC1B ARPC1B MAPK3 MAPK3 ENSMNEP00000015467 ENSMNEP00000015467 MYO1C MYO1C NCKAP1L NCKAP1L MAPK1 MAPK1 WIPF2 WIPF2 ENSMNEP00000011554 ENSMNEP00000011554 NCKAP1 NCKAP1 WASF1 WASF1 VAV3 VAV3 ENSMNEP00000009016 ENSMNEP00000009016 WASF3 WASF3 FYN FYN WIPF3 WIPF3 ABL1 ABL1 MYH9 MYH9 SRC SRC MYO5A MYO5A ENSMNEP00000004647 ENSMNEP00000004647 ACTRT1 ACTRT1 NCKIPSD NCKIPSD ACTL7B ACTL7B ACTR3 ACTR3 ACTG1 ACTG1 ELMO1 ELMO1 CYFIP1 CYFIP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000006433Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa)
WIPF1WAS/WASL interacting protein family member 1. (510 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ARPC4Uncharacterized protein. (78 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ENSMNEP00000045127Uncharacterized protein. (183 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2135 aa)
ENSMNEP00000043922Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (133 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2019 aa)
FGRTyrosine-protein kinase. (529 aa)
ENSMNEP00000041446Uncharacterized protein. (60 aa)
ENSMNEP00000041206Uncharacterized protein; Belongs to the actin family. (163 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
ABI1Abl interactor 1. (508 aa)
ENSMNEP00000038177Uncharacterized protein; Belongs to the actin family. (156 aa)
HCKTyrosine-protein kinase. (504 aa)
LYNTyrosine-protein kinase. (512 aa)
BAIAP2BAI1 associated protein 2. (552 aa)
CD247CD247 molecule. (164 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
ENSMNEP00000032949Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (164 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
CD3GCD3g molecule. (209 aa)
ENSMNEP00000030807Uncharacterized protein. (120 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (377 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ENSMNEP00000029022Uncharacterized protein. (185 aa)
SYKTyrosine-protein kinase. (629 aa)
ENSMNEP00000028540Uncharacterized protein. (139 aa)
BTKTyrosine-protein kinase. (659 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSMNEP00000026694Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (353 aa)
NCK1Cytoplasmic protein. (377 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
YES1Tyrosine-protein kinase. (548 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
CDC42Uncharacterized protein. (191 aa)
WASWASP actin nucleation promoting factor. (545 aa)
ACTBActin beta. (379 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
WASF2WASP family member 2. (499 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (375 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ENSMNEP00000015467Uncharacterized protein. (312 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (968 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
WIPF2WAS/WASL interacting protein family member 2. (246 aa)
ENSMNEP00000011554Uncharacterized protein. (157 aa)
NCKAP1NCK associated protein 1. (1134 aa)
WASF1WASP family member 1. (559 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
ENSMNEP00000009016Uncharacterized protein. (345 aa)
WASF3WASP family member 3. (502 aa)
FYNTyrosine-protein kinase. (537 aa)
WIPF3WAS/WASL interacting protein family member 3. (500 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
SRCTyrosine-protein kinase. (644 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1756 aa)
ENSMNEP00000004647Uncharacterized protein. (185 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
NCKIPSDNCK interacting protein with SH3 domain. (722 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
ACTG1Actin gamma 1. (377 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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