146 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSMD2	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	KLHL18	Kelch like family member 18. (574 aa)
	SLC7A11	Solute carrier family 7 member 11. (514 aa)
	ENSMNEP00000019162	AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
	NQO1	NAD(P)H quinone dehydrogenase 1. (274 aa)
	ME1	Malic enzyme. (572 aa)
	ENSMNEP00000018005	Uncharacterized protein. (133 aa)
	SESN1	Sestrin 1. (551 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	PSMD11	Proteasome 26S subunit, non-ATPase 11. (422 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
	PSMD12	Proteasome 26S subunit, non-ATPase 12. (456 aa)
	ENSMNEP00000016623	Uncharacterized protein. (111 aa)
	PSMD3	Proteasome 26S subunit, non-ATPase 3. (469 aa)
	TXNRD1	Thioredoxin reductase 1. (647 aa)
	IDH1	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (417 aa)
	ENSMNEP00000015212	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (461 aa)
	PSMD8	Proteasome 26S subunit, non-ATPase 8. (350 aa)
	HMOX1	Heme oxygenase 1. (288 aa)
	G6PD	Glucose-6-phosphate dehydrogenase. (561 aa)
	AMER1	APC membrane recruitment protein 1. (990 aa)
	ENSMNEP00000013742	Uncharacterized protein. (293 aa)
	CSNK2B	Uncharacterized protein. (298 aa)
	PSME2	Proteasome activator subunit 2. (254 aa)
	UBXN7	UBX domain-containing protein 7. (481 aa)
	NOTCH1	Notch receptor 1. (2556 aa)
	KIAA2012	KIAA2012. (1180 aa)
	ENSMNEP00000012226	Uncharacterized protein. (104 aa)
	PSMD9	PDZ domain-containing protein. (223 aa)
	PSME4	Proteasome activator subunit 4. (1844 aa)
	ENSMNEP00000011567	Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa)
	PSMC4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
	FBXL17	F-box and leucine rich repeat protein 17. (702 aa)
	ENSMNEP00000010989	Proteasome endopeptidase complex. (241 aa)
	PSMA8	Proteasome subunit alpha type. (250 aa)
	MTFP1	Mitochondrial fission process 1. (166 aa)
	ENSMNEP00000010116	CSN8_PSD8_EIF3K domain-containing protein. (243 aa)
	ENSMNEP00000008478	Ubiquitin-like domain-containing protein. (120 aa)
	ENSMNEP00000008415	Ubiquitin-like domain-containing protein. (83 aa)
	PALB2	Partner and localizer of BRCA2. (1184 aa)
	SKP2	S-phase kinase associated protein 2. (424 aa)
	PSMB8	Proteasome subunit beta. (276 aa)
	SPATA5	Spermatogenesis associated 5. (892 aa)
	PSMC3	AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa)
	BACH1	BTB domain and CNC homolog 1. (736 aa)
	PSMB5	Proteasome subunit beta. (263 aa)
	GCLM	Glutamate-cysteine ligase modifier subunit. (274 aa)
	ENSMNEP00000042738	Uncharacterized protein. (394 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	ENSMNEP00000042381	Uncharacterized protein. (312 aa)
	ENSMNEP00000042218	Uncharacterized protein; Belongs to the SKP1 family. (171 aa)
	ENSMNEP00000041258	Prot_ATP_ID_OB domain-containing protein. (166 aa)
	PSMD10	Proteasome 26S subunit, non-ATPase 10. (226 aa)
	CREBBP	CREB binding protein. (2442 aa)
	EP300	E1A binding protein p300. (2397 aa)
	PSMA2	Proteasome subunit alpha type. (234 aa)
	MUL1	Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
	PSMD4	Proteasome 26S subunit, non-ATPase 4. (403 aa)
	PSMB2	Proteasome subunit beta. (201 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC105475719	Ubiquitin-like domain-containing protein. (127 aa)
	ENSMNEP00000038934	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
	ENSMNEP00000036869	Uncharacterized protein. (97 aa)
	PSMF1	Proteasome inhibitor subunit 1. (271 aa)
	KEAP1	Kelch like ECH associated protein 1. (624 aa)
	ENSMNEP00000036101	Uncharacterized protein. (167 aa)
	NFE2L3	Nuclear factor, erythroid 2 like 3. (693 aa)
	PSMA4	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
	PSMB10	Proteasome subunit beta. (273 aa)
	ENSMNEP00000007573	MPN domain-containing protein. (149 aa)
	PSMD6	Proteasome 26S subunit, non-ATPase 6. (442 aa)
	PRKCD	Protein kinase C. (729 aa)
	SRXN1	Sulfiredoxin. (137 aa)
	PSMB9	Proteasome subunit beta. (219 aa)
	BACH2	BTB domain and CNC homolog 2. (974 aa)
	RBX1	RING-type domain-containing protein. (108 aa)
	NFE2L1	Nuclear factor, erythroid 2 like 1. (772 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	PSMD14	Proteasome 26S subunit, non-ATPase 14. (310 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	PSMB3	Proteasome subunit beta. (205 aa)
	ENSMNEP00000027884	PROTEASOME_ALPHA_1 domain-containing protein. (45 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	TALDO1	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (321 aa)
	ENSMNEP00000035304	Ubiquitin-like domain-containing protein. (134 aa)
	DPP3	Dipeptidyl peptidase 3; Belongs to the peptidase M49 family. (756 aa)
	PSMD5	Proteasome 26S subunit, non-ATPase 5. (493 aa)
	PSMD13	Proteasome 26S subunit, non-ATPase 13. (339 aa)
	TXNRD3	Thioredoxin reductase 3. (642 aa)
	SESN2	Sestrin 2. (480 aa)
	UFD1	Ubiquitin recognition factor in ER associated degradation 1. (308 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (767 aa)
	PSMC1	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
	PRDX1	Peroxiredoxin 1. (199 aa)
	NPLOC4	NPL4 homolog, ubiquitin recognition factor. (565 aa)
	PSMA6	Proteasome subunit alpha type. (246 aa)
	ENSMNEP00000008401	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (433 aa)
	ENSMNEP00000005892	Ubiquitin-like domain-containing protein. (156 aa)
	TRIM21	Tripartite motif containing 21. (475 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
	CSNK2A1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	CSNK2A2	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (345 aa)
	ENSMNEP00000007101	Uncharacterized protein. (191 aa)
	PSME1	Proteasome activator subunit 1. (249 aa)
	NFE2L2	Nuclear factor, erythroid 2 like 2. (618 aa)
	VCP	Valosin containing protein. (767 aa)
	ENSMNEP00000000174	AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
	PSME3	Proteasome activator subunit 3. (265 aa)
	PSMA1	Proteasome subunit alpha type. (269 aa)
	SPATA5L1	Spermatogenesis associated 5 like 1. (753 aa)
	CDKN1A	Cyclin dependent kinase inhibitor 1A. (164 aa)
	PSMD7	Proteasome 26S subunit, non-ATPase 7. (322 aa)
	PGD	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (482 aa)
	ENSMNEP00000005796	Ribosomal_S27 domain-containing protein. (137 aa)
	TKT	Transketolase. (631 aa)
	SQSTM1	Sequestosome 1. (440 aa)
	LOC105475710	Sulfiredoxin. (132 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
	ENSMNEP00000004441	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa)
	ENSMNEP00000004092	Proteasome subunit alpha type. (231 aa)
	ENSMNEP00000004083	Ubiquitin-like domain-containing protein. (127 aa)
	PSMC2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa)
	MAFG	MAF bZIP transcription factor G. (162 aa)
	TRIM58	Tripartite motif containing 58. (486 aa)
	MAFK	MAF bZIP transcription factor K. (156 aa)
	PSMA5	Proteasome subunit alpha type. (241 aa)
	ENSMNEP00000021101	Zf-rbx1 domain-containing protein. (93 aa)
	BRCA1	BRCA1 DNA repair associated. (1894 aa)
	GSR	Glutathione-disulfide reductase. (472 aa)
	PSMB1	Proteasome subunit beta. (241 aa)
	PSMB7	Proteasome subunit beta. (277 aa)
	ENSMNEP00000022472	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	PSMB6	Proteasome subunit beta. (285 aa)
	MAP1LC3B	Uncharacterized protein. (125 aa)
	KLHL17	Kelch like family member 17. (642 aa)
	ENSMNEP00000023008	ANK_REP_REGION domain-containing protein. (159 aa)
	GCLC	Glutamate-cysteine ligase catalytic subunit. (637 aa)
	PSMA3	Proteasome subunit alpha type. (255 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	ENSMNEP00000002753	Ubiquitin-like domain-containing protein. (156 aa)
	ENSMNEP00000024807	1-cysPrx_C domain-containing protein. (94 aa)
	PSMC5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSMNEP00000026038	ENSMNEP00000028923	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.975
AKT1	AKT3	ENSMNEP00000026038	ENSMNEP00000038984	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.932
AKT1	ATF4	ENSMNEP00000026038	ENSMNEP00000028184	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Activating transcription factor 4.	0.788
AKT1	BACH1	ENSMNEP00000026038	ENSMNEP00000043542	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BTB domain and CNC homolog 1.	0.444
AKT1	BACH2	ENSMNEP00000026038	ENSMNEP00000030127	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BTB domain and CNC homolog 2.	0.444
AKT1	BRCA1	ENSMNEP00000026038	ENSMNEP00000021126	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BRCA1 DNA repair associated.	0.973
AKT1	CDKN1A	ENSMNEP00000026038	ENSMNEP00000002098	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cyclin dependent kinase inhibitor 1A.	0.977
AKT1	CREBBP	ENSMNEP00000026038	ENSMNEP00000041109	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CREB binding protein.	0.465
AKT1	CUL1	ENSMNEP00000026038	ENSMNEP00000023203	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cullin 1; Belongs to the cullin family.	0.421
AKT1	EP300	ENSMNEP00000026038	ENSMNEP00000040649	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	E1A binding protein p300.	0.781
AKT1	GSK3B	ENSMNEP00000026038	ENSMNEP00000006148	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.965
AKT1	MYC	ENSMNEP00000026038	ENSMNEP00000004527	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.532
AKT1	NFE2L1	ENSMNEP00000026038	ENSMNEP00000029027	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nuclear factor, erythroid 2 like 1.	0.553
AKT1	NFE2L2	ENSMNEP00000026038	ENSMNEP00000007318	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nuclear factor, erythroid 2 like 2.	0.695
AKT1	NFE2L3	ENSMNEP00000026038	ENSMNEP00000035594	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nuclear factor, erythroid 2 like 3.	0.553
AKT1	NOTCH1	ENSMNEP00000026038	ENSMNEP00000012653	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Notch receptor 1.	0.571
AKT1	RBX1	ENSMNEP00000026038	ENSMNEP00000029606	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RING-type domain-containing protein.	0.404
AKT1	SKP2	ENSMNEP00000026038	ENSMNEP00000045360	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	S-phase kinase associated protein 2.	0.644
AKT2	AKT1	ENSMNEP00000028923	ENSMNEP00000026038	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.975
AKT2	AKT3	ENSMNEP00000028923	ENSMNEP00000038984	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.935