Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FLT1 | IL11 | ENSMNEP00000016356 | ENSMNEP00000012107 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Interleukin 11. | 0.490 |
| FLT1 | IL6 | ENSMNEP00000016356 | ENSMNEP00000000727 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Interleukin 6. | 0.439 |
| HOXA10 | PGR | ENSMNEP00000016481 | ENSMNEP00000005967 | Homeobox A10. | Progesterone receptor. | 0.585 |
| IL10 | IL11 | ENSMNEP00000036763 | ENSMNEP00000012107 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Interleukin 11. | 0.553 |
| IL10 | IL1R1 | ENSMNEP00000036763 | ENSMNEP00000010191 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Interleukin 1 receptor type 1. | 0.491 |
| IL10 | IL6 | ENSMNEP00000036763 | ENSMNEP00000000727 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Interleukin 6. | 0.917 |
| IL10 | TGFB1 | ENSMNEP00000036763 | ENSMNEP00000039914 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.531 |
| IL11 | FLT1 | ENSMNEP00000012107 | ENSMNEP00000016356 | Interleukin 11. | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.490 |
| IL11 | IL10 | ENSMNEP00000012107 | ENSMNEP00000036763 | Interleukin 11. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.553 |
| IL11 | IL6 | ENSMNEP00000012107 | ENSMNEP00000000727 | Interleukin 11. | Interleukin 6. | 0.622 |
| IL1R1 | IL10 | ENSMNEP00000010191 | ENSMNEP00000036763 | Interleukin 1 receptor type 1. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.491 |
| IL1R1 | IL6 | ENSMNEP00000010191 | ENSMNEP00000000727 | Interleukin 1 receptor type 1. | Interleukin 6. | 0.554 |
| IL6 | FLT1 | ENSMNEP00000000727 | ENSMNEP00000016356 | Interleukin 6. | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.439 |
| IL6 | IL10 | ENSMNEP00000000727 | ENSMNEP00000036763 | Interleukin 6. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.917 |
| IL6 | IL11 | ENSMNEP00000000727 | ENSMNEP00000012107 | Interleukin 6. | Interleukin 11. | 0.622 |
| IL6 | IL1R1 | ENSMNEP00000000727 | ENSMNEP00000010191 | Interleukin 6. | Interleukin 1 receptor type 1. | 0.554 |
| IL6 | MMP3 | ENSMNEP00000000727 | ENSMNEP00000041138 | Interleukin 6. | Matrix metallopeptidase 3. | 0.604 |
| IL6 | TGFB1 | ENSMNEP00000000727 | ENSMNEP00000039914 | Interleukin 6. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.594 |
| IL6 | TGFB2 | ENSMNEP00000000727 | ENSMNEP00000041065 | Interleukin 6. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.418 |
| MMP3 | IL6 | ENSMNEP00000041138 | ENSMNEP00000000727 | Matrix metallopeptidase 3. | Interleukin 6. | 0.604 |
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