STRINGSTRING
SSTR5 SSTR5 CXCL1 CXCL1 IL6 IL6 PTGS2 PTGS2 OXTR OXTR SSTR2 SSTR2 CD68 CD68 IL1B IL1B TLR4 TLR4 SST SST PTGFR PTGFR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SSTR5Somatostatin receptor 5; Belongs to the G-protein coupled receptor 1 family. (364 aa)
CXCL1C-X-C motif chemokine. (107 aa)
IL6Interleukin 6. (214 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (402 aa)
CD68CD68 molecule. (354 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa)
SSTSomatostatin. (116 aa)
PTGFRProstaglandin F receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: low (18%) [HD]