(112 nodes) Amino sugar and nucleotide sugar metabolism network (Macaca nemestrina)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	LOC105482555	Rieske domain-containing protein. (590 aa)
	NAGK	N-acetylglucosamine kinase. (360 aa)
	UHMK1	U2AF homology motif kinase 1. (419 aa)
	GMPPA	GDP-mannose pyrophosphorylase A. (425 aa)
	LOC105480962	N-acetyltransferase domain-containing protein. (229 aa)
	METTL7A	Methyltransferase like 7A. (244 aa)
	ETFBKMT	Electron transfer flavoprotein subunit beta lysine methyltransferase. (262 aa)
	LARP4B	La ribonucleoprotein domain family member 4B. (786 aa)
	PGM2	Phosphoglucomutase 2. (612 aa)
	CTBS	Chitobiase; Belongs to the glycosyl hydrolase 18 family. (382 aa)
	NIPAL1	NIPA like domain containing 1. (410 aa)
	PMM1	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (262 aa)
	FAM149B1	Family with sequence similarity 149 member B1. (584 aa)
	PI16	Peptidase inhibitor 16; Belongs to the CRISP family. (468 aa)
	CHIT1	Chitinase 1; Belongs to the glycosyl hydrolase 18 family. (466 aa)
	SLC25A24	Solute carrier family 25 member 24; Belongs to the mitochondrial carrier (TC 2.A.29) family. (477 aa)
	METTL21C	Methyltransferase like 21C. (284 aa)
	HK1	Hexokinase 1. (921 aa)
	FPGT	Fucose-1-phosphate guanylyltransferase. (607 aa)
	GLIPR1L1	GLIPR1 like 1; Belongs to the CRISP family. (240 aa)
	M1AP	Meiosis 1 associated protein. (530 aa)
	UBASH3B	Ubiquitin associated and SH3 domain containing B. (649 aa)
	GCKR	Glucokinase regulator. (625 aa)
	PMM2	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (246 aa)
	HEXA	Beta-hexosaminidase. (538 aa)
	LOC105479216	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (472 aa)
	FAM149A	Family with sequence similarity 149 member A. (789 aa)
	CYB5R2	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (322 aa)
	METTL7B	Methyltransferase like 7B. (244 aa)
	LOC105475223	Glucose-6-phosphate isomerase; Belongs to the GPI family. (446 aa)
	UBASH3A	Ubiquitin associated and SH3 domain containing A. (631 aa)
	CRISP2	Cysteine rich secretory protein 2; Belongs to the CRISP family. (278 aa)
	HK3	Hexokinase 3. (960 aa)
	GFPT2	Glutamine-fructose-6-phosphate transaminase 2. (682 aa)
	SYPL1	Synaptophysin like 1. (262 aa)
	SLC25A41	Solute carrier family 25 member 41; Belongs to the mitochondrial carrier (TC 2.A.29) family. (334 aa)
	METTL23	Methyltransferase like 23. (190 aa)
	GLT8D2	Glycosyltransferase 8 domain containing 2. (349 aa)
	PGM3	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family. (599 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (573 aa)
	CHIA	Chitinase acidic; Belongs to the glycosyl hydrolase 18 family. (470 aa)
	GNPNAT1	Glucosamine 6-phosphate N-acetyltransferase. (184 aa)
	SYP	Synaptophysin. (313 aa)
	SLC25A23	Solute carrier family 25 member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family. (499 aa)
	SYPL2	Synaptophysin like 2. (270 aa)
	NIPAL4	NIPA like domain containing 4. (462 aa)
	NAA10	N(alpha)-acetyltransferase 10, NatA catalytic subunit. (235 aa)
	METTL21A	Methyltransferase like 21A. (236 aa)
	LARP4	La ribonucleoprotein domain family member 4. (703 aa)
	CYB5R3	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (333 aa)
	HAS1	Hyaluronan synthase 1. (581 aa)
	SNX8	Sorting nexin 8. (465 aa)
	GMDS	GDP-mannose 4,6-dehydratase. (372 aa)
	RABGGTB	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (331 aa)
	NIPA2	NIPA magnesium transporter 2. (360 aa)
	OXNAD1	Oxidoreductase NAD binding domain containing 1. (312 aa)
	CRISP3	Cysteine rich secretory protein 3; Belongs to the CRISP family. (245 aa)
	HAS2	Hyaluronan synthase 2. (552 aa)
	NIPAL2	NIPA like domain containing 2. (383 aa)
	EDF1	Endothelial differentiation related factor 1. (147 aa)
	HEXB	Beta-hexosaminidase. (557 aa)
	HK2	Hexokinase 2. (917 aa)
	OVGP1	Oviductal glycoprotein 1; Belongs to the glycosyl hydrolase 18 family. (635 aa)
	MS4A14	Membrane spanning 4-domains A14. (714 aa)
	GLT8D1	Glycosyltransferase 8 domain containing 1. (371 aa)
	GCK	Phosphotransferase. (466 aa)
	AMDHD2	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. (409 aa)
	TSTA3	Tissue specific transplantation antigen P35B. (321 aa)
	GNPDA2	Glucosamine-6-phosphate isomerase. (276 aa)
	SYNPR	Synaptoporin. (285 aa)
	UAP1L1	UDP-N-acetylglucosamine pyrophosphorylase 1 like 1. (508 aa)
	ENSMNEP00000028677	HTH La-type RNA-binding domain-containing protein. (552 aa)
	NAA11	N-acetyltransferase domain-containing protein. (229 aa)
	LOC105463702	HTH cro/C1-type domain-containing protein. (148 aa)
	CHI3L2	Chitinase 3 like 2; Belongs to the glycosyl hydrolase 18 family. (381 aa)
	NPL	N-acetylneuraminate pyruvate lyase; Belongs to the DapA family. (320 aa)
	NANP	N-acetylneuraminic acid phosphatase. (150 aa)
	GNE	Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase. (753 aa)
	PI15	Peptidase inhibitor 15; Belongs to the CRISP family. (258 aa)
	ENSMNEP00000029881	Uncharacterized protein. (241 aa)
	RENBP	Renin binding protein. (431 aa)
	UGP2	UTP--glucose-1-phosphate uridylyltransferase. (517 aa)
	NANS	N-acetylneuraminate synthase. (359 aa)
	CYB5R4	Cytochrome b5 reductase 4. (521 aa)
	NIPA1	NIPA magnesium transporter 1. (327 aa)
	GNPDA1	Glucosamine-6-phosphate isomerase. (289 aa)
	HAS3	Hyaluronan synthase 3. (586 aa)
	PGM1	Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (580 aa)
	LMCD1	LIM and cysteine rich domains 1. (365 aa)
	UAP1	UDP-N-acetylglucosamine pyrophosphorylase 1. (522 aa)
	GALK1	Galactokinase 1. (422 aa)
	UXS1	UDP-glucuronate decarboxylase 1. (420 aa)
	GLIPR2	GLI pathogenesis related 2; Belongs to the CRISP family. (165 aa)
	CYB5RL	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (315 aa)
	GMPPB	GDP-mannose pyrophosphorylase B. (387 aa)
	MPI	Mannose-6-phosphate isomerase. (423 aa)
	CRISP1	Cysteine rich secretory protein 1; Belongs to the CRISP family. (249 aa)
	HKDC1	Hexokinase domain containing 1. (917 aa)
	UGDH	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (489 aa)
	NFU1	NFU1 iron-sulfur cluster scaffold. (228 aa)
	CHI3L1	Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (405 aa)
	VCPKMT	Valosin containing protein lysine methyltransferase. (235 aa)
	GALE	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)
	PGM5	Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
	FCSK	Fucose kinase. (1062 aa)
	GFPT1	Glutamine--fructose-6-phosphate transaminase 1. (699 aa)
	NIPAL3	NIPA like domain containing 3. (406 aa)
	SLC25A25	Solute carrier family 25 member 25; Belongs to the mitochondrial carrier (TC 2.A.29) family. (512 aa)
	CYB5R1	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
	GLIPR1	GLI pathogenesis related 1; Belongs to the CRISP family. (247 aa)
	ENSMNEP00000044132	Glucosamine 6-phosphate N-acetyltransferase. (152 aa)
	CMAS	Cytidine monophosphate N-acetylneuraminic acid synthetase. (434 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMDHD2	ENSMNEP00000044132	ENSMNEP00000026961	ENSMNEP00000044132	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucosamine 6-phosphate N-acetyltransferase.	0.868
AMDHD2	FAM149A	ENSMNEP00000026961	ENSMNEP00000011188	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Family with sequence similarity 149 member A.	0.508
AMDHD2	FAM149B1	ENSMNEP00000026961	ENSMNEP00000005479	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Family with sequence similarity 149 member B1.	0.508
AMDHD2	GALE	ENSMNEP00000026961	ENSMNEP00000039398	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.562
AMDHD2	GALK1	ENSMNEP00000026961	ENSMNEP00000033187	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Galactokinase 1.	0.415
AMDHD2	GCK	ENSMNEP00000026961	ENSMNEP00000026883	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Phosphotransferase.	0.447
AMDHD2	GCKR	ENSMNEP00000026961	ENSMNEP00000008380	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucokinase regulator.	0.908
AMDHD2	GFPT1	ENSMNEP00000026961	ENSMNEP00000040752	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glutamine--fructose-6-phosphate transaminase 1.	0.878
AMDHD2	GFPT2	ENSMNEP00000026961	ENSMNEP00000013551	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glutamine-fructose-6-phosphate transaminase 2.	0.933
AMDHD2	GMPPA	ENSMNEP00000026961	ENSMNEP00000000981	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	GDP-mannose pyrophosphorylase A.	0.701
AMDHD2	GMPPB	ENSMNEP00000026961	ENSMNEP00000035125	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	GDP-mannose pyrophosphorylase B.	0.701
AMDHD2	GNE	ENSMNEP00000026961	ENSMNEP00000029528	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase.	0.909
AMDHD2	GNPDA1	ENSMNEP00000026961	ENSMNEP00000032033	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucosamine-6-phosphate isomerase.	0.996
AMDHD2	GNPDA2	ENSMNEP00000026961	ENSMNEP00000027169	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucosamine-6-phosphate isomerase.	0.997
AMDHD2	GNPNAT1	ENSMNEP00000026961	ENSMNEP00000018603	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucosamine 6-phosphate N-acetyltransferase.	0.868
AMDHD2	GPI	ENSMNEP00000026961	ENSMNEP00000017100	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.751
AMDHD2	HEXA	ENSMNEP00000026961	ENSMNEP00000009164	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Beta-hexosaminidase.	0.528
AMDHD2	HEXB	ENSMNEP00000026961	ENSMNEP00000025386	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Beta-hexosaminidase.	0.544
AMDHD2	HK1	ENSMNEP00000026961	ENSMNEP00000007631	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Hexokinase 1.	0.885
AMDHD2	HK2	ENSMNEP00000026961	ENSMNEP00000025441	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Hexokinase 2.	0.885