36 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC46A1	Solute carrier family 46 member 1. (459 aa)
	IL6	Interleukin 6. (214 aa)
	ENSMNEP00000002533	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
	FOLR2	Folate receptor beta. (267 aa)
	FOLR1	Folate receptor alpha. (257 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (968 aa)
	SLC19A1	Solute carrier family 19 member 1. (586 aa)
	GGH	Folate gamma-glutamyl hydrolase. (318 aa)
	IZUMO1R	IZUMO1 receptor, JUNO. (280 aa)
	ABCC5	ATP binding cassette subfamily C member 5. (1404 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
	ABCC4	ATP binding cassette subfamily C member 4. (1325 aa)
	ABCC3	ATP binding cassette subfamily C member 3. (1526 aa)
	ENSMNEP00000016913	DHFR domain-containing protein. (141 aa)
	DHFR	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
	ABCC1	ATP binding cassette subfamily C member 1. (1498 aa)
	ENSMNEP00000019152	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (175 aa)
	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (592 aa)
	ALOX12	Arachidonate 12-lipoxygenase, 12S type. (663 aa)
	ABCG2	ABC transporter domain-containing protein. (655 aa)
	GART	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (548 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	ABCC2	ATP binding cassette subfamily C member 2. (1545 aa)
	ENSMNEP00000030582	DHFR domain-containing protein. (132 aa)
	ENSMNEP00000031036	Uncharacterized protein. (200 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa)
	TYMS	Thymidylate synthetase. (313 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
	ENSMNEP00000036183	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (175 aa)
	ENSMNEP00000037412	SHMT domain-containing protein. (417 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
	MTHFR	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (697 aa)
	FPGS	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (590 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (478 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC1	ABCG2	ENSMNEP00000018876	ENSMNEP00000023872	ATP binding cassette subfamily C member 1.	ABC transporter domain-containing protein.	0.761
ABCC2	ABCG2	ENSMNEP00000030093	ENSMNEP00000023872	ATP binding cassette subfamily C member 2.	ABC transporter domain-containing protein.	0.877
ABCC3	ABCG2	ENSMNEP00000016302	ENSMNEP00000023872	ATP binding cassette subfamily C member 3.	ABC transporter domain-containing protein.	0.509
ABCC4	ABCG2	ENSMNEP00000014745	ENSMNEP00000023872	ATP binding cassette subfamily C member 4.	ABC transporter domain-containing protein.	0.438
ABCC5	ABCG2	ENSMNEP00000012684	ENSMNEP00000023872	ATP binding cassette subfamily C member 5.	ABC transporter domain-containing protein.	0.431
ABCG2	ABCC1	ENSMNEP00000023872	ENSMNEP00000018876	ABC transporter domain-containing protein.	ATP binding cassette subfamily C member 1.	0.761
ABCG2	ABCC2	ENSMNEP00000023872	ENSMNEP00000030093	ABC transporter domain-containing protein.	ATP binding cassette subfamily C member 2.	0.877
ABCG2	ABCC3	ENSMNEP00000023872	ENSMNEP00000016302	ABC transporter domain-containing protein.	ATP binding cassette subfamily C member 3.	0.509
ABCG2	ABCC4	ENSMNEP00000023872	ENSMNEP00000014745	ABC transporter domain-containing protein.	ATP binding cassette subfamily C member 4.	0.438
ABCG2	ABCC5	ENSMNEP00000023872	ENSMNEP00000012684	ABC transporter domain-containing protein.	ATP binding cassette subfamily C member 5.	0.431
ATIC	DHFR	ENSMNEP00000019636	ENSMNEP00000018367	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.879
ATIC	ENSMNEP00000002533	ENSMNEP00000019636	ENSMNEP00000002533	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.879
ATIC	ENSMNEP00000016913	ENSMNEP00000019636	ENSMNEP00000016913	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	DHFR domain-containing protein.	0.879
ATIC	ENSMNEP00000019152	ENSMNEP00000019636	ENSMNEP00000019152	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.879
ATIC	ENSMNEP00000030582	ENSMNEP00000019636	ENSMNEP00000030582	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	DHFR domain-containing protein.	0.542
ATIC	ENSMNEP00000036183	ENSMNEP00000019636	ENSMNEP00000036183	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.879
ATIC	ENSMNEP00000037412	ENSMNEP00000019636	ENSMNEP00000037412	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	SHMT domain-containing protein.	0.952
ATIC	FPGS	ENSMNEP00000019636	ENSMNEP00000040227	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.590
ATIC	GART	ENSMNEP00000019636	ENSMNEP00000027789	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.999
ATIC	GGH	ENSMNEP00000019636	ENSMNEP00000011542	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Folate gamma-glutamyl hydrolase.	0.497