STRINGSTRING
TGFBR1 TGFBR1 CXCL10 CXCL10 CCL19 CCL19 TNFSF12 TNFSF12 CCR3 CCR3 CCL14 CCL14 IFNG IFNG PRL PRL ENSMNEP00000044834 ENSMNEP00000044834 CNTFR CNTFR TNFRSF25 TNFRSF25 IL27RA IL27RA IL6R IL6R TNFRSF19 TNFRSF19 CCL21 CCL21 CCL27 CCL27 IL12A IL12A CCL1 CCL1 GH1 GH1 INHBC INHBC CXCL11 CXCL11 LOC105498430 LOC105498430 LOC105483028 LOC105483028 ACVR2A ACVR2A TGFB3 TGFB3 CCL15 CCL15 NGFR NGFR CSF2RA CSF2RA BMP8A BMP8A CCL25 CCL25 ENSMNEP00000041110 ENSMNEP00000041110 TGFB2 TGFB2 IL37 IL37 MPL MPL IL5RA IL5RA TNFRSF13C TNFRSF13C TNFRSF8 TNFRSF8 CD4 CD4 IL18 IL18 TGFB1 TGFB1 AMHR2 AMHR2 IL2RB IL2RB PPBP PPBP IL17RC IL17RC IL3 IL3 XCL1 XCL1 INHA INHA IFNGR1 IFNGR1 IL20RA IL20RA CCR2 CCR2 IL18R1 IL18R1 TNFRSF10D TNFRSF10D IL1RN IL1RN BMP10 BMP10 RELCH RELCH EDAR EDAR TNFRSF4 TNFRSF4 PF4 PF4 IL33 IL33 OSM OSM INHBA INHBA ACVR1B ACVR1B TNFSF14 TNFSF14 CXCL16 CXCL16 CCL20 CCL20 CCL13 CCL13 IL27 IL27 IFNA14 IFNA14 IL10 IL10 IFNAR2 IFNAR2 IL21R IL21R IL23R IL23R IL13RA2 IL13RA2 LOC105495378 LOC105495378 CSF1R CSF1R GDF1 GDF1 TGFBR2 TGFBR2 IL17A IL17A CCR10 CCR10 GALT GALT IL2RA IL2RA EPOR EPOR BMPR1B BMPR1B FASLG FASLG IL17RB IL17RB IL2 IL2 CXCL9 CXCL9 CRELD1 CRELD1 IL17B IL17B IL6 IL6 CXCR3 CXCR3 IFNA6 IFNA6 IL34 IL34 TNFRSF14 TNFRSF14 IL20RB IL20RB BMP7 BMP7 CD27 CD27 ACKR3 ACKR3 ACVR1C ACVR1C LOC105483006 LOC105483006 IL5 IL5 CD40 CD40 ENSMNEP00000002263 ENSMNEP00000002263 ACKR4 ACKR4 GDF15 GDF15 CCR4 CCR4 IL36B IL36B CXCL14 CXCL14 CCL26 CCL26 CCL24 CCL24 IL13 IL13 IL36G IL36G TNFRSF11A TNFRSF11A CRLF2 CRLF2 IL12RB1 IL12RB1 CCL28 CCL28 TNFSF15 TNFSF15 XCR1 XCR1 IL9 IL9 EDA2R EDA2R MSTN MSTN IL20 IL20 FAS FAS IL24 IL24 CSF3 CSF3 ADGRA1 ADGRA1 DR1 DR1 CCL11 CCL11 LOC105477295 LOC105477295 IL15RA IL15RA CCR9 CCR9 GDF5 GDF5 TNFSF8 TNFSF8 CXCL12 CXCL12 GHR GHR OSMR OSMR IL1R1 IL1R1 IL9R IL9R IL22 IL22 TNFRSF6B TNFRSF6B IL31 IL31 LOC105471157 LOC105471157 TNFRSF1A TNFRSF1A CCL18 CCL18 JAGN1 JAGN1 TNFRSF17 TNFRSF17 PRLR PRLR FCGBP FCGBP INHBB INHBB IL11 IL11 LTBR LTBR IL10RB IL10RB CCR5 CCR5 CCR7 CCR7 LOC105468574 LOC105468574 ADGRA3 ADGRA3 ENSMNEP00000013313 ENSMNEP00000013313 IL21 IL21 LOC105483030 LOC105483030 LTB LTB ENSMNEP00000013537 ENSMNEP00000013537 TNFRSF13B TNFRSF13B IL1RL2 IL1RL2 IL2RG IL2RG CX3CR1 CX3CR1 IL7R IL7R TNFSF11 TNFSF11 GDF3 GDF3 LOC105477292 LOC105477292 LOC105485704 LOC105485704 IFNL1 IFNL1 CXCL1 CXCL1 TNFSF13B TNFSF13B CXCR5 CXCR5 TNFRSF21 TNFRSF21 CD70 CD70 TNFSF9 TNFSF9 IL4R IL4R TSLP TSLP CXCR4 CXCR4 BMPR2 BMPR2 THPO THPO TNFSF18 TNFSF18 IL12RB2 IL12RB2 CCL22 CCL22 BMP5 BMP5 CCL17 CCL17 BMPR1A BMPR1A AMH AMH ADGRA2 ADGRA2 LEPR LEPR ENSMNEP00000018637 ENSMNEP00000018637 TNFRSF12A TNFRSF12A LOC105477289 LOC105477289 GDF11 GDF11 CX3CL1 CX3CL1 ENSMNEP00000019155 ENSMNEP00000019155 SCN4A SCN4A CCR6 CCR6 IL12B IL12B ACVR2B ACVR2B CSF3R CSF3R ZAN ZAN TNFRSF18 TNFRSF18 IL17D IL17D IL4 IL4 CCL16 CCL16 PF4V1 PF4V1 BMP8B BMP8B LOC105485104 LOC105485104 TNFRSF10A TNFRSF10A CCL23 CCL23 IFNLR1 IFNLR1 CCL5 CCL5 CLCF1 CLCF1 CXCL17 CXCL17 CXCL8 CXCL8 LEP LEP IFNGR2 IFNGR2 BMP15 BMP15 IL10RA IL10RA TNFRSF9 TNFRSF9 IL19 IL19 IL6ST IL6ST CSF2RB CSF2RB BMP6 BMP6 ENSMNEP00000023427 ENSMNEP00000023427 TNFRSF10B TNFRSF10B TNFSF4 TNFSF4 CXCL13 CXCL13 GDF6 GDF6 IL17C IL17C IL1R2 IL1R2 LIFR LIFR IL22RA1 IL22RA1 TNFRSF1B TNFRSF1B CXCL6 CXCL6 RUFY4 RUFY4 IL23A IL23A CCL7 CCL7 IL26 IL26 NODAL NODAL BMP4 BMP4 IL17RA IL17RA GDF9 GDF9 LOC105493010 LOC105493010 GDF7 GDF7 CTF1 CTF1 BMP2 BMP2 CXCR6 CXCR6 IL1RAP IL1RAP GDF10 GDF10 PURG PURG IL31RA IL31RA NGF NGF CSF2 CSF2 LOC105469367 LOC105469367 IL25 IL25 ACVR1 ACVR1 LOC105468986 LOC105468986 LDAH LDAH IL18RAP IL18RAP IL16 IL16 CSF1 CSF1 RTEL1-2 RTEL1-2 IL1F10 IL1F10 IL17RE IL17RE IFNB1 IFNB1 TNF TNF LOC105498418 LOC105498418 ACVRL1 ACVRL1 IL7 IL7 IFNE IFNE LIF LIF IL17F IL17F RTEL1 RTEL1 CCL2 CCL2 IL13RA1 IL13RA1 EDA EDA TNFSF10 TNFSF10 GDF2 GDF2 CD40LG CD40LG TNFSF13 TNFSF13 IL36RN IL36RN IL36A IL36A LTA LTA SUCO SUCO TNFRSF11B TNFRSF11B IL1B IL1B IL15 IL15 IL1A IL1A EPO EPO LOC105485102 LOC105485102 RELT RELT BMP3 BMP3 INHBE INHBE IL3RA IL3RA CCL8 CCL8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
CXCL10C-X-C motif chemokine 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (98 aa)
CCL19C-C motif chemokine. (123 aa)
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa)
CCL14C-C motif chemokine ligand 14. (108 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
PRLProlactin. (227 aa)
ENSMNEP00000044834Uncharacterized protein. (122 aa)
CNTFRCiliary neurotrophic factor receptor. (372 aa)
TNFRSF25TNF receptor superfamily member 25. (420 aa)
IL27RAInterleukin 27 receptor subunit alpha. (636 aa)
IL6RInterleukin 6 receptor. (467 aa)
TNFRSF19TNF receptor superfamily member 19. (417 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
CCL27C-C motif chemokine ligand 27. (112 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
CCL1C-C motif chemokine. (96 aa)
GH1Uncharacterized protein. (217 aa)
INHBCInhibin subunit beta C. (352 aa)
CXCL11C-X-C motif chemokine. (96 aa)
LOC105498430Uncharacterized protein. (189 aa)
LOC105483028Uncharacterized protein. (217 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CCL15C-C motif chemokine. (109 aa)
NGFRNerve growth factor receptor. (439 aa)
CSF2RAColony stimulating factor 2 receptor alpha subunit. (390 aa)
BMP8ATGF_BETA_2 domain-containing protein. (402 aa)
CCL25C-C motif chemokine ligand 25. (165 aa)
ENSMNEP00000041110Uncharacterized protein. (177 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
IL37Interleukin-1. (235 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (641 aa)
IL5RAInterleukin 5 receptor subunit alpha. (420 aa)
TNFRSF13CTNF receptor superfamily member 13C. (172 aa)
TNFRSF8TNF receptor superfamily member 8. (595 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (572 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
PPBPC-X-C motif chemokine. (128 aa)
IL17RCInterleukin 17 receptor C. (787 aa)
IL3Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (151 aa)
XCL1SCY domain-containing protein. (114 aa)
INHAInhibin subunit alpha. (384 aa)
IFNGR1Interferon gamma receptor 1. (488 aa)
IL20RAInterleukin 20 receptor subunit alpha. (552 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
IL18R1Interleukin 18 receptor 1. (540 aa)
TNFRSF10DTNF receptor superfamily member 10d. (383 aa)
IL1RNInterleukin-1. (179 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
EDAREctodysplasin A receptor. (480 aa)
TNFRSF4TNF receptor superfamily member 4. (277 aa)
PF4C-X-C motif chemokine. (90 aa)
IL33Interleukin 33. (270 aa)
OSMOncostatin M. (252 aa)
INHBAInhibin subunit beta A. (426 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
CXCL16C-X-C motif chemokine ligand 16. (276 aa)
CCL20C-C motif chemokine. (96 aa)
CCL13C-C motif chemokine. (98 aa)
IL27Interleukin 27. (243 aa)
IFNA14Interferon alpha 14. (137 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
IFNAR2Uncharacterized protein. (516 aa)
IL21RInterleukin 21 receptor. (538 aa)
IL23RInterleukin 23 receptor. (576 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (388 aa)
LOC105495378Uncharacterized protein. (200 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
GDF1TGF_BETA_2 domain-containing protein. (370 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
IL17AInterleukin 17A. (155 aa)
CCR10C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (362 aa)
GALTGalactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (783 aa)
IL2RAInterleukin 2 receptor subunit alpha. (272 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (508 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
FASLGTumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa)
IL17RBInterleukin 17 receptor B. (502 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)
CXCL9C-X-C motif chemokine ligand 9. (125 aa)
CRELD1Cysteine rich with EGF like domains 1. (422 aa)
IL17BInterleukin 17B. (180 aa)
IL6Interleukin 6. (214 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
IFNA6Interferon alpha 6. (190 aa)
IL34Interleukin 34. (242 aa)
TNFRSF14TNF receptor superfamily member 14. (280 aa)
IL20RBInterleukin 20 receptor subunit beta. (311 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
CD27CD27 molecule. (260 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
LOC105483006Uncharacterized protein. (197 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
CD40CD40 molecule. (278 aa)
ENSMNEP00000002263Uncharacterized protein. (329 aa)
ACKR4Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
GDF15Growth differentiation factor 15. (308 aa)
CCR4C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
IL36BInterleukin 36 beta. (164 aa)
CXCL14C-X-C motif chemokine ligand 14. (111 aa)
CCL26C-C motif chemokine ligand 26. (62 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
IL13Interleukin 13. (146 aa)
IL36GInterleukin-1. (169 aa)
TNFRSF11ATNF receptor superfamily member 11a. (616 aa)
CRLF2Cytokine receptor like factor 2. (305 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (678 aa)
CCL28C-C motif chemokine. (127 aa)
TNFSF15TNF superfamily member 15. (255 aa)
XCR1X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
IL9Interleukin 9. (145 aa)
EDA2REctodysplasin A2 receptor. (318 aa)
MSTNMyostatin. (375 aa)
IL20Interleukin 20. (176 aa)
FASTumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa)
IL24Interleukin 24. (207 aa)
CSF3Colony stimulating factor 3. (207 aa)
ADGRA1Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family. (562 aa)
DR1Down-regulator of transcription 1. (176 aa)
CCL11C-C motif chemokine. (97 aa)
LOC105477295C-X-C motif chemokine. (114 aa)
IL15RAInterleukin 15 receptor subunit alpha. (301 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
GDF5Growth differentiation factor 5. (499 aa)
TNFSF8TNF superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
GHRGrowth hormone receptor. (645 aa)
OSMROncostatin M receptor. (977 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
IL9RInterleukin 9 receptor. (514 aa)
IL22Interleukin 22. (179 aa)
TNFRSF6BTNF receptor superfamily member 6b. (300 aa)
IL31Interleukin 31. (163 aa)
LOC105471157C-X-C motif chemokine. (103 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
CCL18C-C motif chemokine. (88 aa)
JAGN1Jagunal homolog 1. (183 aa)
TNFRSF17TNF receptor superfamily member 17. (183 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
FCGBPFc fragment of IgG binding protein. (3551 aa)
INHBBInhibin subunit beta B. (407 aa)
IL11Interleukin 11. (199 aa)
LTBRLymphotoxin beta receptor. (435 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
CCR5C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (379 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
LOC105468574C-C motif chemokine. (92 aa)
ADGRA3Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1319 aa)
ENSMNEP00000013313Uncharacterized protein. (152 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
LOC105483030Uncharacterized protein. (199 aa)
LTBLymphotoxin beta; Belongs to the tumor necrosis factor family. (244 aa)
ENSMNEP00000013537C-C motif chemokine. (103 aa)
TNFRSF13BTNF receptor superfamily member 13B. (293 aa)
IL1RL2Interleukin 1 receptor like 2. (562 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa)
IL7RInterleukin 7 receptor. (459 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
GDF3Growth differentiation factor 3. (364 aa)
LOC105477292C-X-C motif chemokine. (154 aa)
LOC105485704Uncharacterized protein. (87 aa)
IFNL1Interferon lambda 1. (202 aa)
CXCL1C-X-C motif chemokine. (107 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
TNFRSF21TNF receptor superfamily member 21. (655 aa)
CD70TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (316 aa)
TNFSF9TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa)
IL4RInterleukin 4 receptor. (825 aa)
TSLPThymic stromal lymphopoietin. (159 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (409 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
THPOThrombopoietin. (353 aa)
TNFSF18TNF superfamily member 18. (199 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (842 aa)
CCL22C-C motif chemokine ligand 22. (93 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
CCL17C-C motif chemokine. (91 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
AMHAnti-Mullerian hormone. (562 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1340 aa)
LEPRLeptin receptor. (1163 aa)
ENSMNEP00000018637Uncharacterized protein. (309 aa)
TNFRSF12AUncharacterized protein. (227 aa)
LOC105477289C-X-C motif chemokine. (114 aa)
GDF11Growth differentiation factor 11. (459 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (407 aa)
ENSMNEP00000019155Interfer-bind domain-containing protein. (338 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (379 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
CSF3RColony stimulating factor 3 receptor. (836 aa)
ZANZonadhesin (gene/pseudogene). (2561 aa)
TNFRSF18TNF receptor superfamily member 18. (241 aa)
IL17DInterleukin 17D. (202 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
CCL16C-C motif chemokine. (112 aa)
PF4V1C-X-C motif chemokine. (101 aa)
BMP8BTGF_BETA_2 domain-containing protein. (402 aa)
LOC105485104C-C motif chemokine. (92 aa)
TNFRSF10ATNF receptor superfamily member 10a. (309 aa)
CCL23C-C motif chemokine. (120 aa)
IFNLR1Interferon lambda receptor 1. (525 aa)
CCL5C-C motif chemokine. (91 aa)
CLCF1Cardiotrophin like cytokine factor 1. (230 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
CXCL8Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
IFNGR2Interferon gamma receptor 2. (312 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
IL10RAInterleukin 10 receptor subunit alpha. (580 aa)
TNFRSF9TNF receptor superfamily member 9. (254 aa)
IL19Interleukin 19. (214 aa)
IL6STInterleukin 6 signal transducer. (942 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (918 aa)
BMP6Bone morphogenetic protein 6. (513 aa)
ENSMNEP00000023427Uncharacterized protein. (198 aa)
TNFRSF10BTNF receptor superfamily member 10b. (445 aa)
TNFSF4TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
CXCL13C-X-C motif chemokine. (109 aa)
GDF6Growth differentiation factor 6. (455 aa)
IL17CInterleukin 17C. (197 aa)
IL1R2Interleukin 1 receptor type 2. (398 aa)
LIFRLIF receptor subunit alpha. (1097 aa)
IL22RA1Interleukin 22 receptor subunit alpha 1. (574 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
CXCL6C-X-C motif chemokine. (123 aa)
RUFY4RUN and FYVE domain containing 4. (571 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
CCL7C-C motif chemokine. (105 aa)
IL26Interleukin 26. (171 aa)
NODALNodal growth differentiation factor. (347 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
IL17RAInterleukin 17 receptor A. (865 aa)
GDF9Growth differentiation factor 9. (455 aa)
LOC105493010SCY domain-containing protein. (114 aa)
GDF7Growth differentiation factor 7. (448 aa)
CTF1Cardiotrophin 1. (201 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
CXCR6C-X-C chemokine receptor type 6; Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. (383 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
PURGPurine rich element binding protein G. (322 aa)
IL31RAInterleukin 31 receptor A. (763 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (123 aa)
CSF2Colony stimulating factor 2. (144 aa)
LOC105469367Uncharacterized protein. (147 aa)
IL25Interleukin 25. (160 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
LOC105468986Uncharacterized protein. (227 aa)
LDAHLipid droplet associated hydrolase. (372 aa)
IL18RAPInterleukin 18 receptor accessory protein. (598 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1378 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa)
RTEL1-2Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1117 aa)
IL1F10Interleukin-1. (152 aa)
IL17REInterleukin 17 receptor E. (696 aa)
IFNB1Interferon beta 1. (187 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
LOC105498418Uncharacterized protein. (190 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
IL7Interleukin 7. (184 aa)
IFNEInterferon epsilon. (194 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
IL17FInterleukin 17F. (163 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1354 aa)
CCL2C-C motif chemokine. (99 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (425 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
GDF2Growth differentiation factor 2. (429 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa)
TNFSF13TNF superfamily member 13; Belongs to the tumor necrosis factor family. (250 aa)
IL36RNInterleukin-1. (155 aa)
IL36AInterleukin-1. (179 aa)
LTALymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa)
SUCOSUN domain containing ossification factor. (1384 aa)
TNFRSF11BTNF receptor superfamily member 11b. (428 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (224 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
LOC105485102C-C motif chemokine. (92 aa)
RELTRELT TNF receptor. (440 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa)
INHBEInhibin subunit beta E. (351 aa)
IL3RAInterleukin 3 receptor subunit alpha. (346 aa)
CCL8C-C motif chemokine. (109 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: medium (46%) [HD]