STRINGSTRING
PPBP PPBP XCL1 XCL1 IL20RA IL20RA CCR2 CCR2 IL18R1 IL18R1 TNFRSF10D TNFRSF10D PF4 PF4 TNFSF14 TNFSF14 CCL20 CCL20 CCL13 CCL13 IL10 IL10 CSF1R CSF1R CCR10 CCR10 IL2RA IL2RA CCL8 CCL8 LOC105485102 LOC105485102 LTA LTA TNFSF10 TNFSF10 CCL2 CCL2 TNF TNF CSF1 CSF1 IL18RAP IL18RAP LOC105493010 LOC105493010 CCL7 CCL7 IL2 IL2 CXCL9 CXCL9 IL6 IL6 CXCR3 CXCR3 IL34 IL34 TNFRSF14 TNFRSF14 IL20RB IL20RB ACKR3 ACKR3 ACKR4 ACKR4 CCR4 CCR4 CXCL14 CXCL14 CCL26 CCL26 CCL24 CCL24 CCL28 CCL28 XCR1 XCR1 IL20 IL20 IL24 IL24 CCL11 CCL11 LOC105477295 LOC105477295 CCR9 CCR9 CXCL12 CXCL12 LOC105471157 LOC105471157 TNFRSF1A TNFRSF1A CCL18 CCL18 LTBR LTBR IL10RB IL10RB CCR5 CCR5 CCR7 CCR7 LOC105468574 LOC105468574 ENSMNEP00000013537 ENSMNEP00000013537 IL2RG IL2RG CX3CR1 CX3CR1 LOC105477292 LOC105477292 LOC105485704 LOC105485704 CXCL1 CXCL1 CXCR5 CXCR5 CXCR4 CXCR4 CCL22 CCL22 CCL17 CCL17 LOC105477289 LOC105477289 CX3CL1 CX3CL1 CCR6 CCR6 CCL16 CCL16 PF4V1 PF4V1 LOC105485104 LOC105485104 TNFRSF10A TNFRSF10A CCL23 CCL23 CCL5 CCL5 CXCL8 CXCL8 IL10RA IL10RA IL19 IL19 IL6ST IL6ST TNFRSF10B TNFRSF10B CXCL13 CXCL13 IL22RA1 IL22RA1 TNFRSF1B TNFRSF1B CXCL6 CXCL6 RUFY4 RUFY4 IL2RB IL2RB IL18 IL18 IL37 IL37 CCL25 CCL25 CCL15 CCL15 CXCL11 CXCL11 CCL1 CCL1 CCL27 CCL27 CCL21 CCL21 IL6R IL6R ENSMNEP00000044834 ENSMNEP00000044834 CCL14 CCL14 CCR3 CCR3 CCL19 CCL19 CXCL10 CXCL10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPBPC-X-C motif chemokine. (128 aa)
XCL1SCY domain-containing protein. (114 aa)
IL20RAInterleukin 20 receptor subunit alpha. (552 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
IL18R1Interleukin 18 receptor 1. (540 aa)
TNFRSF10DTNF receptor superfamily member 10d. (383 aa)
PF4C-X-C motif chemokine. (90 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
CCL20C-C motif chemokine. (96 aa)
CCL13C-C motif chemokine. (98 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
CCR10C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (362 aa)
IL2RAInterleukin 2 receptor subunit alpha. (272 aa)
CCL8C-C motif chemokine. (109 aa)
LOC105485102C-C motif chemokine. (92 aa)
LTALymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
CCL2C-C motif chemokine. (99 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa)
IL18RAPInterleukin 18 receptor accessory protein. (598 aa)
LOC105493010SCY domain-containing protein. (114 aa)
CCL7C-C motif chemokine. (105 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)
CXCL9C-X-C motif chemokine ligand 9. (125 aa)
IL6Interleukin 6. (214 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
IL34Interleukin 34. (242 aa)
TNFRSF14TNF receptor superfamily member 14. (280 aa)
IL20RBInterleukin 20 receptor subunit beta. (311 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
ACKR4Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
CCR4C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
CXCL14C-X-C motif chemokine ligand 14. (111 aa)
CCL26C-C motif chemokine ligand 26. (62 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
CCL28C-C motif chemokine. (127 aa)
XCR1X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
IL20Interleukin 20. (176 aa)
IL24Interleukin 24. (207 aa)
CCL11C-C motif chemokine. (97 aa)
LOC105477295C-X-C motif chemokine. (114 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
LOC105471157C-X-C motif chemokine. (103 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
CCL18C-C motif chemokine. (88 aa)
LTBRLymphotoxin beta receptor. (435 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
CCR5C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (379 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
LOC105468574C-C motif chemokine. (92 aa)
ENSMNEP00000013537C-C motif chemokine. (103 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa)
LOC105477292C-X-C motif chemokine. (154 aa)
LOC105485704Uncharacterized protein. (87 aa)
CXCL1C-X-C motif chemokine. (107 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (409 aa)
CCL22C-C motif chemokine ligand 22. (93 aa)
CCL17C-C motif chemokine. (91 aa)
LOC105477289C-X-C motif chemokine. (114 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (407 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (379 aa)
CCL16C-C motif chemokine. (112 aa)
PF4V1C-X-C motif chemokine. (101 aa)
LOC105485104C-C motif chemokine. (92 aa)
TNFRSF10ATNF receptor superfamily member 10a. (309 aa)
CCL23C-C motif chemokine. (120 aa)
CCL5C-C motif chemokine. (91 aa)
CXCL8Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
IL10RAInterleukin 10 receptor subunit alpha. (580 aa)
IL19Interleukin 19. (214 aa)
IL6STInterleukin 6 signal transducer. (942 aa)
TNFRSF10BTNF receptor superfamily member 10b. (445 aa)
CXCL13C-X-C motif chemokine. (109 aa)
IL22RA1Interleukin 22 receptor subunit alpha 1. (574 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
CXCL6C-X-C motif chemokine. (123 aa)
RUFY4RUN and FYVE domain containing 4. (571 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
IL37Interleukin-1. (235 aa)
CCL25C-C motif chemokine ligand 25. (165 aa)
CCL15C-C motif chemokine. (109 aa)
CXCL11C-X-C motif chemokine. (96 aa)
CCL1C-C motif chemokine. (96 aa)
CCL27C-C motif chemokine ligand 27. (112 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
IL6RInterleukin 6 receptor. (467 aa)
ENSMNEP00000044834Uncharacterized protein. (122 aa)
CCL14C-C motif chemokine ligand 14. (108 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa)
CCL19C-C motif chemokine. (123 aa)
CXCL10C-X-C motif chemokine 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (98 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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