STRINGSTRING
EFCAB13 EFCAB13 PIK3CB PIK3CB ENSMNEP00000001215 ENSMNEP00000001215 ENSMNEP00000001669 ENSMNEP00000001669 CALML3 CALML3 LRRN4CL LRRN4CL TPTE2 TPTE2 PI4K2B PI4K2B PIP5K1B PIP5K1B IP6K1 IP6K1 DGKI DGKI INPP5A INPP5A PLCG2 PLCG2 PLS1 PLS1 PIP5K1A PIP5K1A SYNJ2 SYNJ2 PI4K2A PI4K2A ITPR2 ITPR2 PIP5K1C PIP5K1C SASH3 SASH3 PRKCB PRKCB PPIP5K1 PPIP5K1 PI4KB PI4KB CCDC180 CCDC180 PIP4P1 PIP4P1 PLCD3 PLCD3 BSCL2 BSCL2 PTEN PTEN PIP4P2 PIP4P2 PLCB3 PLCB3 PLCB2 PLCB2 INPP5D INPP5D PIK3R2 PIK3R2 PLCD4 PLCD4 PLCB4 PLCB4 SAMSN1 SAMSN1 PIP4K2B PIP4K2B PIP4K2C PIP4K2C MTMR3 MTMR3 TASOR TASOR ITPKC ITPKC MTMR1 MTMR1 ITPKA ITPKA PSORS1C2 PSORS1C2 MORN2 MORN2 PLCE1 PLCE1 IMPAD1 IMPAD1 CDS2 CDS2 INPP5E INPP5E TNS2 TNS2 MTMR8 MTMR8 INPPL1 INPPL1 MTMR6 MTMR6 MTM1 MTM1 PIK3C2A PIK3C2A ENSMNEP00000016414 ENSMNEP00000016414 ITPK1 ITPK1 INPP5F INPP5F PI4KA PI4KA ITPKB ITPKB DGKB DGKB IPMK IPMK CALML4 CALML4 DGKQ DGKQ CDS1 CDS1 SACM1L SACM1L DGKA DGKA INPP4B INPP4B INPP5B INPP5B ENSMNEP00000020112 ENSMNEP00000020112 PIK3CA PIK3CA ASB12 ASB12 DGKK DGKK DGKE DGKE PLS3 PLS3 PIK3C2G PIK3C2G MTMR10 MTMR10 RBM18 RBM18 PIK3C3 PIK3C3 UNCX UNCX ITPR1 ITPR1 PVALEF PVALEF CALML6 CALML6 MTMR14 MTMR14 ITPR3 ITPR3 CALM2 CALM2 RTCA RTCA PIP4K2A PIP4K2A PRKCA PRKCA PRKCG PRKCG DGKH DGKH CALM3 CALM3 IP6K3 IP6K3 DGKG DGKG PIK3R1 PIK3R1 IMPA1 IMPA1 PIK3CD PIK3CD IMPA2 IMPA2 INPP1 INPP1 PLCZ1 PLCZ1 OCRL OCRL ENSMNEP00000032785 ENSMNEP00000032785 SHROOM4 SHROOM4 CENPF CENPF ENSMNEP00000034103 ENSMNEP00000034103 SYNJ1 SYNJ1 MTMR7 MTMR7 CDIPT CDIPT IPPK IPPK TNS4 TNS4 TNS3 TNS3 PLCD1 PLCD1 PIKFYVE PIKFYVE SHROOM3 SHROOM3 INSC INSC SASH1 SASH1 LCP1 LCP1 PIK3R3 PIK3R3 INPP4A INPP4A PLCG1 PLCG1 EFCAB3 EFCAB3 DGKZ DGKZ TNS1 TNS1 SBF1 SBF1 BICD1 BICD1 IP6K2 IP6K2 SBF2 SBF2 CALM1 CALM1 MTMR2 MTMR2 MTMR4 MTMR4 DGKD DGKD PIK3C2B PIK3C2B PPIP5K2 PPIP5K2 BICD2 BICD2 PLCB1 PLCB1 MTMR12 MTMR12 SAMD5 SAMD5 ENSMNEP00000046105 ENSMNEP00000046105
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFCAB13EF-hand calcium binding domain 13. (925 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
ENSMNEP00000001215Uncharacterized protein. (87 aa)
ENSMNEP00000001669Uncharacterized protein. (77 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
LRRN4CLLRRN4 C-terminal like. (238 aa)
TPTE2Uncharacterized protein. (558 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2 beta. (462 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (554 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
DGKIDiacylglycerol kinase. (1079 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (412 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PLS1Plastin 1. (629 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (612 aa)
SYNJ2Synaptojanin 2. (1496 aa)
PI4K2APhosphatidylinositol 4-kinase type 2 alpha. (480 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (705 aa)
SASH3SAM and SH3 domain containing 3. (382 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PPIP5K1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1408 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (832 aa)
CCDC180Coiled-coil domain containing 180. (1670 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)
PLCD3Phosphoinositide phospholipase C. (791 aa)
BSCL2BSCL2 lipid droplet biogenesis associated, seipin. (467 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1174 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1203 aa)
PIK3R2Uncharacterized protein. (668 aa)
PLCD4Phosphoinositide phospholipase C. (768 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
SAMSN1SAM domain, SH3 domain and nuclear localization signals 1. (441 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (398 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
MTMR3Myotubularin related protein 3. (1207 aa)
TASORTranscription activation suppressor. (1612 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (683 aa)
MTMR1Myotubularin related protein 1. (672 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
PSORS1C2Psoriasis susceptibility 1 candidate 2. (136 aa)
MORN2MORN repeat containing 2. (79 aa)
PLCE1Phosphoinositide phospholipase C. (2295 aa)
IMPAD1Inositol monophosphatase domain containing 1. (304 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa)
INPP5EInositol polyphosphate-5-phosphatase E. (630 aa)
TNS2Tensin 2. (1432 aa)
MTMR8Myotubularin related protein 8. (710 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1333 aa)
MTMR6Myotubularin related protein 6. (621 aa)
MTM1Myotubularin 1. (603 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1688 aa)
ENSMNEP00000016414Uncharacterized protein; Belongs to the calmodulin family. (179 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (414 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1133 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2118 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (945 aa)
DGKBDiacylglycerol kinase. (803 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (401 aa)
CALML4Calmodulin like 4. (193 aa)
DGKQDiacylglycerol kinase. (957 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa)
SACM1LSAC1 like phosphatidylinositide phosphatase. (554 aa)
DGKADiacylglycerol kinase. (735 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (938 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (891 aa)
ENSMNEP00000020112Uncharacterized protein. (166 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ASB12Ankyrin repeat and SOCS box containing 12. (318 aa)
DGKKDiacylglycerol kinase. (1265 aa)
DGKEDiacylglycerol kinase. (567 aa)
PLS3Plastin 3. (639 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1486 aa)
MTMR10Myotubularin related protein 10. (775 aa)
RBM18RNA binding motif protein 18. (190 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa)
UNCXUNC homeobox. (501 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
CALML6Calmodulin like 6. (181 aa)
MTMR14Myotubularin related protein 14. (650 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
CALM2Calmodulin 1; Belongs to the calmodulin family. (149 aa)
RTCARNA 3'-terminal phosphate cyclase. (309 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
DGKHDiacylglycerol kinase. (1220 aa)
CALM3Calmodulin 3. (149 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (410 aa)
DGKGDiacylglycerol kinase. (791 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
IMPA1Inositol-1-monophosphatase. (309 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
INPP1Inositol polyphosphate-1-phosphatase. (399 aa)
PLCZ1Phosphoinositide phospholipase C. (639 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (900 aa)
ENSMNEP00000032785PIPK domain-containing protein. (470 aa)
SHROOM4Shroom family member 4. (1498 aa)
CENPFCentromere protein F. (3077 aa)
ENSMNEP00000034103Uncharacterized protein. (1637 aa)
SYNJ1Synaptojanin 1. (1653 aa)
MTMR7Myotubularin related protein 7. (660 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (213 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (491 aa)
TNS4Tensin 4. (710 aa)
TNS3Tensin 3. (1481 aa)
PLCD1Phosphoinositide phospholipase C. (731 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
SHROOM3Shroom family member 3. (1996 aa)
INSCINSC spindle orientation adaptor protein. (579 aa)
SASH1SAM and SH3 domain containing 1. (1246 aa)
LCP1Lymphocyte cytosolic protein 1. (630 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (463 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (977 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
EFCAB3EF-hand calcium binding domain 3. (488 aa)
DGKZDiacylglycerol kinase. (1172 aa)
TNS1Tensin 1. (1908 aa)
SBF1SET binding factor 1. (1897 aa)
BICD1BICD cargo adaptor 1. (975 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (475 aa)
SBF2SET binding factor 2. (1849 aa)
CALM1Calmodulin 1. (149 aa)
MTMR2Myotubularin related protein 2. (643 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
DGKDDiacylglycerol kinase. (1216 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1278 aa)
BICD2BICD cargo adaptor 2. (855 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
MTMR12Myotubularin related protein 12. (743 aa)
SAMD5Sterile alpha motif domain containing 5. (173 aa)
ENSMNEP00000046105Uncharacterized protein. (81 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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