STRINGSTRING
TTC14 TTC14 ATG2B ATG2B GABARAPL2 GABARAPL2 RPTOR RPTOR ATG7 ATG7 ENSMNEP00000007890 ENSMNEP00000007890 ATG13 ATG13 MTOR MTOR ATG16L1 ATG16L1 ATG9A ATG9A ENSMNEP00000011766 ENSMNEP00000011766 ULK2 ULK2 BECN1 BECN1 ENSMNEP00000015675 ENSMNEP00000015675 ATG5 ATG5 ATG12 ATG12 WIPI2 WIPI2 LOC105496847 LOC105496847 PIK3C3 PIK3C3 ATG9B ATG9B PIK3R4 PIK3R4 ATG4B ATG4B ATG101 ATG101 ATG4C ATG4C ULK3 ULK3 ATG4A ATG4A ATG2A ATG2A ENSMNEP00000033022 ENSMNEP00000033022 GABARAPL1 GABARAPL1 MLST8 MLST8 ATG10 ATG10 WIPI1 WIPI1 PPP2CB PPP2CB ATG3 ATG3 PPP2CA PPP2CA IGBP1 IGBP1 ATG4D ATG4D GABARAP GABARAP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TTC14Tetratricopeptide repeat domain 14. (771 aa)
ATG2BAutophagy related 2B. (2078 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa)
ENSMNEP00000007890Uncharacterized protein. (340 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa)
ATG16L1Autophagy related 16 like 1. (624 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (851 aa)
ENSMNEP00000011766Uncharacterized protein. (272 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1035 aa)
BECN1Beclin 1. (450 aa)
ENSMNEP00000015675Uncharacterized protein. (105 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (451 aa)
LOC105496847Uncharacterized protein. (362 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (508 aa)
ATG101Autophagy related 101. (218 aa)
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
ULK3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa)
ATG2AAutophagy related 2A. (1968 aa)
ENSMNEP00000033022Uncharacterized protein. (77 aa)
GABARAPL1GABA type A receptor associated protein like 1. (146 aa)
MLST8MTOR associated protein, LST8 homolog. (335 aa)
ATG10Autophagy related 10. (228 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (462 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ATG3Autophagy-related protein 3. (314 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
IGBP1Uncharacterized protein. (339 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (447 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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