STRINGSTRING
ENSMNEP00000000052 ENSMNEP00000000052 REM1 REM1 TFEC TFEC ERAS ERAS LOC105475719 LOC105475719 ENSMNEP00000002753 ENSMNEP00000002753 BCL2L1 BCL2L1 FUNDC2 FUNDC2 ENSMNEP00000004083 ENSMNEP00000004083 GABARAPL2 GABARAPL2 SQSTM1 SQSTM1 USP8 USP8 FIS1 FIS1 ENSMNEP00000005796 ENSMNEP00000005796 ENSMNEP00000005892 ENSMNEP00000005892 E2F1 E2F1 CSNK2A1 CSNK2A1 SRC SRC BNIP3 BNIP3 PDIK1L PDIK1L PRKN PRKN CSNK2A2 CSNK2A2 REM2 REM2 RAB7B RAB7B ENSMNEP00000008415 ENSMNEP00000008415 ENSMNEP00000008478 ENSMNEP00000008478 LOC105492577 LOC105492577 MRAS MRAS ATG9A ATG9A MAPK8 MAPK8 CSNK2B CSNK2B TAX1BP1 TAX1BP1 BECN1 BECN1 ENSMNEP00000015675 ENSMNEP00000015675 PGAM5 PGAM5 CFAP70 CFAP70 PINK1 PINK1 RRAS RRAS UBA52 UBA52 ATG5 ATG5 BNIP3L BNIP3L EIF2AK3 EIF2AK3 USP31 USP31 USP19 USP19 AGFG2 AGFG2 RAB7A RAB7A ULK1 ULK1 USP15 USP15 RASL11B RASL11B NPAS3 NPAS3 TFE3 TFE3 TFEB TFEB MITF MITF USP4 USP4 TOMM7 TOMM7 ATG9B ATG9B RPS27A RPS27A ATF4 ATF4 RELA RELA UBB UBB RIT2 RIT2 NPAS1 NPAS1 CITED2 CITED2 HIF3A HIF3A STK35 STK35 RHOT2 RHOT2 TP53 TP53 HRAS HRAS RIT1 RIT1 ENSMNEP00000033022 ENSMNEP00000033022 FOXO3 FOXO3 METTL17 METTL17 FUNDC1 FUNDC1 RRAS2 RRAS2 GABARAPL1 GABARAPL1 ENSMNEP00000035304 ENSMNEP00000035304 USP11 USP11 MFN1 MFN1 TBC1D17 TBC1D17 SP1 SP1 USP43 USP43 AMBRA1 AMBRA1 MAPK9 MAPK9 CALCOCO2 CALCOCO2 RRAD RRAD ENSMNEP00000038142 ENSMNEP00000038142 USP32 USP32 OPTN OPTN SPEN SPEN GEM GEM NBR1 NBR1 AGFG1 AGFG1 MAPK10 MAPK10 TBK1 TBK1 HIF1A HIF1A RHOT1 RHOT1 USP30 USP30 ENSMNEP00000043248 ENSMNEP00000043248 GABARAP GABARAP MFN2 MFN2 NRAS NRAS TBC1D15 TBC1D15 KRAS KRAS CSDE1 CSDE1 BCL2L13 BCL2L13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000000052Ubiquitin-like domain-containing protein. (92 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
TFECTranscription factor EC. (347 aa)
ERASES cell expressed Ras. (233 aa)
LOC105475719Ubiquitin-like domain-containing protein. (127 aa)
ENSMNEP00000002753Ubiquitin-like domain-containing protein. (156 aa)
BCL2L1BCL2 like 1. (233 aa)
FUNDC2FUN14 domain containing 2. (189 aa)
ENSMNEP00000004083Ubiquitin-like domain-containing protein. (127 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
SQSTM1Sequestosome 1. (440 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1082 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
ENSMNEP00000005796Ribosomal_S27 domain-containing protein. (137 aa)
ENSMNEP00000005892Ubiquitin-like domain-containing protein. (156 aa)
E2F1E2F transcription factor 1. (437 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
SRCTyrosine-protein kinase. (644 aa)
BNIP3BCL2 interacting protein 3. (253 aa)
PDIK1LPDLIM1 interacting kinase 1 like; Belongs to the protein kinase superfamily. (341 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (345 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
ENSMNEP00000008415Ubiquitin-like domain-containing protein. (83 aa)
ENSMNEP00000008478Ubiquitin-like domain-containing protein. (120 aa)
LOC105492577Uncharacterized protein. (151 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (851 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
CSNK2BUncharacterized protein. (298 aa)
TAX1BP1Tax1 binding protein 1. (805 aa)
BECN1Beclin 1. (450 aa)
ENSMNEP00000015675Uncharacterized protein. (105 aa)
PGAM5Uncharacterized protein. (140 aa)
CFAP70Cilia and flagella associated protein 70. (1120 aa)
PINK1PTEN induced kinase 1. (581 aa)
RRASRAS related. (218 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
BNIP3LBCL2 interacting protein 3 like. (219 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
USP31Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1215 aa)
USP19Ubiquitin specific peptidase 19. (1421 aa)
AGFG2ArfGAP with FG repeats 2. (447 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
RASL11BRAS like family 11 member B. (248 aa)
NPAS3Neuronal PAS domain protein 3. (814 aa)
TFE3Transcription factor binding to IGHM enhancer 3. (575 aa)
TFEBTranscription factor EB. (490 aa)
MITFMelanocyte inducing transcription factor. (517 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa)
TOMM7Uncharacterized protein. (126 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ATF4Activating transcription factor 4. (351 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
UBBUbiquitin B. (196 aa)
RIT2Ras like without CAAX 2. (217 aa)
NPAS1Neuronal PAS domain protein 1. (591 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
HIF3AHypoxia inducible factor 3 subunit alpha. (570 aa)
STK35Serine/threonine kinase 35. (533 aa)
RHOT2Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (618 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (270 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
RIT1Ras like without CAAX 1. (219 aa)
ENSMNEP00000033022Uncharacterized protein. (77 aa)
FOXO3Forkhead box O3. (716 aa)
METTL17Methyltransferase like 17. (459 aa)
FUNDC1FUN14 domain containing 1. (155 aa)
RRAS2RAS related 2. (204 aa)
GABARAPL1GABA type A receptor associated protein like 1. (146 aa)
ENSMNEP00000035304Ubiquitin-like domain-containing protein. (134 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (978 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (688 aa)
TBC1D17TBC1 domain family member 17. (648 aa)
SP1Sp1 transcription factor. (786 aa)
USP43Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1012 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
MAPK9Mitogen-activated protein kinase 9. (354 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (465 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
ENSMNEP00000038142Uncharacterized protein. (194 aa)
USP32Uncharacterized protein; Belongs to the peptidase C19 family. (1612 aa)
OPTNOptineurin. (571 aa)
SPENSpen family transcriptional repressor. (3673 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
NBR1NBR1 autophagy cargo receptor. (960 aa)
AGFG1ArfGAP with FG repeats 1. (586 aa)
MAPK10Mitogen-activated protein kinase. (489 aa)
TBK1TANK binding kinase 1. (729 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
RHOT1Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (658 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
ENSMNEP00000043248Uncharacterized protein. (82 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
TBC1D15TBC1 domain family member 15. (691 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CSDE1Cold shock domain containing E1. (844 aa)
BCL2L13BCL2 like 13. (509 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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