STRINGSTRING
LDAH LDAH GSK3B GSK3B TRPC6 TRPC6 ENSMNEP00000005419 ENSMNEP00000005419 NFATC3 NFATC3 SRMS SRMS ENSMNEP00000004647 ENSMNEP00000004647 WNT5A WNT5A PTPN11 PTPN11 ITGB1 ITGB1 PAK2 PAK2 LRRC4C LRRC4C EPHA8 EPHA8 PLCG2 PLCG2 BOC BOC EPHA5 EPHA5 SEMA7A SEMA7A UNC5A UNC5A BMP7 BMP7 LOC105482353 LOC105482353 ERAS ERAS PIK3CB PIK3CB EPHB6 EPHB6 PAK5 PAK5 SEMA4A SEMA4A TRPC5 TRPC5 ABLIM2 ABLIM2 ABL1 ABL1 PTK6 PTK6 TRPC4 TRPC4 ROBO1 ROBO1 PIK3R2 PIK3R2 RAC3 RAC3 FYN FYN NTN1 NTN1 RASA1 RASA1 SEMA3C SEMA3C EFNA5 EFNA5 SEMA4B SEMA4B SEMA3B SEMA3B NTNG1 NTNG1 CXCL12 CXCL12 EFNA3 EFNA3 SRGAP3 SRGAP3 SRGAP1 SRGAP1 WNT4 WNT4 SEMA4G SEMA4G PLXNA3 PLXNA3 PLXNC1 PLXNC1 UNC5C UNC5C TRPC3 TRPC3 ILK ILK EPHB4 EPHB4 EFNB3 EFNB3 ENSMNEP00000011554 ENSMNEP00000011554 ENSMNEP00000011594 ENSMNEP00000011594 MAPK1 MAPK1 NFATC4 NFATC4 ENSMNEP00000012679 ENSMNEP00000012679 SLIT1 SLIT1 TRPC1 TRPC1 SSH1 SSH1 ABLIM1 ABLIM1 ROBO3 ROBO3 DPYSL2 DPYSL2 SSH3 SSH3 MAPK3 MAPK3 PARD6G PARD6G EPHA6 EPHA6 RYK RYK ENSMNEP00000016854 ENSMNEP00000016854 PLXNB3 PLXNB3 CXCR4 CXCR4 RRAS RRAS BMPR2 BMPR2 PAK4 PAK4 MYL5 MYL5 SEMA6A SEMA6A PPP3CB PPP3CB EPHA10 EPHA10 NTNG2 NTNG2 RAC2 RAC2 ENAH ENAH EPHA4 EPHA4 SEMA4D SEMA4D ARHGEF12 ARHGEF12 CFL1 CFL1 DPYSL5 DPYSL5 SRGAP2 SRGAP2 PIK3CA PIK3CA ENSMNEP00000027695 ENSMNEP00000027695 LRRC4 LRRC4 PPP3CA PPP3CA RHOC RHOC PARD6A PARD6A GDF7 GDF7 LIMK2 LIMK2 EFNA1 EFNA1 SLIT3 SLIT3 EPHA3 EPHA3 NCK1 NCK1 SEMA6D SEMA6D PTK2 PTK2 GNAI3 GNAI3 NGEF NGEF SEMA6C SEMA6C PARD6B PARD6B SEMA6B SEMA6B ROBO2 ROBO2 EPHA7 EPHA7 EFNB1 EFNB1 PARD3 PARD3 NFATC2 NFATC2 ADAM15 ADAM15 CDC42 CDC42 RGMA RGMA RHOD RHOD SMO SMO GNAI2 GNAI2 CCDC125 CCDC125 SRC SRC CAMK2D CAMK2D CSDE1 CSDE1 EPHB1 EPHB1 KRAS KRAS ENSMNEP00000045127 ENSMNEP00000045127 PAK6 PAK6 PAK1 PAK1 NRAS NRAS PDK1 PDK1 ENSMNEP00000044158 ENSMNEP00000044158 NTN4 NTN4 DCC DCC SEMA3E SEMA3E CDK5 CDK5 CAMK2A CAMK2A ROCK2 ROCK2 SEMA5A SEMA5A MYL9 MYL9 LOC105474026 LOC105474026 ABLIM3 ABLIM3 PPP3R1 PPP3R1 SEMA3D SEMA3D ENSMNEP00000041202 ENSMNEP00000041202 EPHA2 EPHA2 SLIT2 SLIT2 RGS3 RGS3 SEMA3G SEMA3G PPP3CC PPP3CC PLCG1 PLCG1 L1CAM L1CAM SEMA4F SEMA4F FES FES PIK3R3 PIK3R3 RHOA RHOA SHH SHH PLXNB2 PLXNB2 NEO1 NEO1 EPHB3 EPHB3 EPHB2 EPHB2 EPHA1 EPHA1 UNC5B UNC5B SEMA4C SEMA4C SEMA5B SEMA5B CAMK2G CAMK2G LIMK1 LIMK1 ENSMNEP00000036315 ENSMNEP00000036315 MYL12A MYL12A TRPC7 TRPC7 SEMA3A SEMA3A PLXNA2 PLXNA2 RAF1 RAF1 BMPR1B BMPR1B FZD3 FZD3 PLXNB1 PLXNB1 PLXNA1 PLXNA1 EFNA2 EFNA2 PAK3 PAK3 NTN3 NTN3 ARSI ARSI PLXNA4 PLXNA4 CAMK2B CAMK2B HRAS HRAS CFL2 CFL2 RAC1 RAC1 PTCH1 PTCH1 NCK2 NCK2 PIK3CD PIK3CD PIK3R1 PIK3R1 EFNA4 EFNA4 GNAI1 GNAI1 MET MET RND1 RND1 NRP1 NRP1 EFNB2 EFNB2 SSH2 SSH2 PRKCZ PRKCZ ENSMNEP00000029022 ENSMNEP00000029022 ENSMNEP00000028956 ENSMNEP00000028956 ROCK1 ROCK1 PRKCA PRKCA UNC5D UNC5D WNT5B WNT5B SEMA3F SEMA3F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LDAHLipid droplet associated hydrolase. (372 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
ENSMNEP00000005419Uncharacterized protein. (114 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
SRMSTyrosine-protein kinase. (492 aa)
ENSMNEP00000004647Uncharacterized protein. (185 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
PAK2Non-specific serine/threonine protein kinase. (501 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
EPHA8EPH receptor A8. (999 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1116 aa)
EPHA5EPH receptor A5. (1038 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (697 aa)
UNC5AUnc-5 netrin receptor A. (912 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
LOC105482353Uncharacterized protein. (172 aa)
ERASES cell expressed Ras. (233 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
EPHB6EPH receptor B6. (1017 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
ABLIM2Actin binding LIM protein family member 2. (651 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
PTK6Tyrosine-protein kinase. (397 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (978 aa)
ROBO1Roundabout guidance receptor 1. (1539 aa)
PIK3R2Uncharacterized protein. (668 aa)
RAC3Rac family small GTPase 3. (192 aa)
FYNTyrosine-protein kinase. (537 aa)
NTN1Netrin 1. (604 aa)
RASA1RAS p21 protein activator 1. (1046 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (975 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (749 aa)
NTNG1Netrin G1. (539 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
EFNA3Ephrin A3; Belongs to the ephrin family. (238 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1099 aa)
SRGAP1Uncharacterized protein. (525 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
PLXNA3Plexin A3. (1871 aa)
PLXNC1Plexin C1. (1568 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
ILKIntegrin linked kinase. (528 aa)
EPHB4EPH receptor B4. (987 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
ENSMNEP00000011554Uncharacterized protein. (157 aa)
ENSMNEP00000011594Uncharacterized protein. (512 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
NFATC4Nuclear factor of activated T cells 4. (961 aa)
ENSMNEP00000012679Uncharacterized protein. (262 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
SSH1Slingshot protein phosphatase 1. (1122 aa)
ABLIM1Actin binding LIM protein 1. (778 aa)
ROBO3Roundabout guidance receptor 3. (1384 aa)
DPYSL2Dihydropyrimidinase like 2. (677 aa)
SSH3Slingshot protein phosphatase 3. (657 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PARD6GPar-6 family cell polarity regulator gamma. (376 aa)
EPHA6EPH receptor A6. (1131 aa)
RYKReceptor like tyrosine kinase. (606 aa)
ENSMNEP00000016854ADF-H domain-containing protein. (135 aa)
PLXNB3Plexin B3. (1909 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (409 aa)
RRASRAS related. (218 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
PAK4Non-specific serine/threonine protein kinase. (702 aa)
MYL5Myosin light chain 5. (168 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
EPHA10EPH receptor A10. (1014 aa)
NTNG2Netrin G2. (530 aa)
RAC2Rac family small GTPase 2. (192 aa)
ENAHENAH actin regulator. (790 aa)
EPHA4EPH receptor A4. (997 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1484 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (196 aa)
DPYSL5Dihydropyrimidinase like 5. (564 aa)
SRGAP2Uncharacterized protein. (1071 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSMNEP00000027695Uncharacterized protein. (445 aa)
LRRC4Leucine rich repeat containing 4. (633 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
RHOCRas homolog family member C. (193 aa)
PARD6APar-6 family cell polarity regulator alpha. (344 aa)
GDF7Growth differentiation factor 7. (448 aa)
LIMK2LIM domain kinase 2. (638 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
EPHA3EPH receptor A3. (984 aa)
NCK1Cytoplasmic protein. (377 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1086 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa)
GNAI3G protein subunit alpha i3. (328 aa)
NGEFNeuronal guanine nucleotide exchange factor. (713 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (962 aa)
PARD6BPar-6 family cell polarity regulator beta. (372 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (887 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
EPHA7EPH receptor A7. (998 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
PARD3Par-3 family cell polarity regulator. (1353 aa)
NFATC2Nuclear factor of activated T cells 2. (921 aa)
ADAM15ADAM metallopeptidase domain 15. (861 aa)
CDC42Uncharacterized protein. (191 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (458 aa)
RHODRas homolog family member D. (210 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (657 aa)
GNAI2G protein subunit alpha i2. (355 aa)
CCDC125Coiled-coil domain containing 125. (510 aa)
SRCTyrosine-protein kinase. (644 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
CSDE1Cold shock domain containing E1. (844 aa)
EPHB1EPH receptor B1. (984 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ENSMNEP00000045127Uncharacterized protein. (183 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PDK1Protein-serine/threonine kinase. (436 aa)
ENSMNEP00000044158Protein kinase domain-containing protein. (279 aa)
NTN4Netrin 4. (628 aa)
DCCDCC netrin 1 receptor. (1352 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
SEMA5ASemaphorin 5A. (1074 aa)
MYL9Myosin light chain 9. (172 aa)
LOC105474026Uncharacterized protein. (559 aa)
ABLIM3Actin binding LIM protein family member 3. (690 aa)
PPP3R1Uncharacterized protein. (189 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
ENSMNEP00000041202ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (209 aa)
EPHA2EPH receptor A2. (976 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
RGS3Regulator of G protein signaling 3. (916 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (782 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
L1CAML1 cell adhesion molecule. (1257 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (463 aa)
RHOARas homolog family member A. (193 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa)
PLXNB2Plexin B2. (1898 aa)
NEO1Neogenin 1. (1498 aa)
EPHB3EPH receptor B3. (1008 aa)
EPHB2EPH receptor B2. (1063 aa)
EPHA1EPH receptor A1. (970 aa)
UNC5BUnc-5 netrin receptor B. (946 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
SEMA5BSemaphorin 5B. (1150 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (556 aa)
LIMK1LIM domain kinase 1. (677 aa)
ENSMNEP00000036315Uncharacterized protein. (182 aa)
MYL12AMyosin light chain 12A. (177 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
PLXNA2Plexin A2. (1909 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (668 aa)
PLXNB1Plexin B1. (2140 aa)
PLXNA1Plexin A1. (1907 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (213 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
NTN3Netrin 3. (580 aa)
ARSIArylsulfatase family member I. (569 aa)
PLXNA4Plexin A4. (1950 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
RAC1Rac family small GTPase 1. (211 aa)
PTCH1Patched 1. (1449 aa)
NCK2Cytoplasmic protein. (382 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
EFNA4Ephrin A4; Belongs to the ephrin family. (206 aa)
GNAI1G protein subunit alpha i1. (422 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1403 aa)
RND1Rho family GTPase 1. (232 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (925 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (336 aa)
SSH2Slingshot protein phosphatase 2. (1383 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
ENSMNEP00000029022Uncharacterized protein. (185 aa)
ENSMNEP00000028956Uncharacterized protein. (185 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
UNC5DUnc-5 netrin receptor D. (958 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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