STRINGSTRING
CLDN2 CLDN2 NRCAM NRCAM ITGA9 ITGA9 ICAM3 ICAM3 LOC105474426 LOC105474426 CNTN1 CNTN1 PTPRT PTPRT ENSMNEP00000043350 ENSMNEP00000043350 LOC105474413 LOC105474413 CNTN4 CNTN4 MAG MAG CD274 CD274 CNTN5 CNTN5 VTCN1 VTCN1 CTLA4 CTLA4 NRXN2 NRXN2 CNTNAP2 CNTNAP2 ITGA4 ITGA4 HLA-DOB HLA-DOB ITGAL ITGAL CDH2 CDH2 CADM1 CADM1 CD4 CD4 ENSMNEP00000040169 ENSMNEP00000040169 CD99L2 CD99L2 CDH5 CDH5 L1CAM L1CAM CLDN24 CLDN24 Mane-DRB1 Mane-DRB1 ENSMNEP00000039202 ENSMNEP00000039202 ENSMNEP00000038649 ENSMNEP00000038649 TRBV27 TRBV27 DNMT3L DNMT3L CLDN7 CLDN7 NEO1 NEO1 ENSMNEP00000037129 ENSMNEP00000037129 NLGN3 NLGN3 PTPRK PTPRK MPZL1 MPZL1 NRXN3 NRXN3 CD34 CD34 NTM NTM SELP SELP SDC4 SDC4 HLA-DPA1 HLA-DPA1 GABPA GABPA ENSMNEP00000035333 ENSMNEP00000035333 Mane-B Mane-B ITGA6 ITGA6 ITGAM ITGAM NECTIN1 NECTIN1 AZGP1 AZGP1 CDH1 CDH1 TRAV22 TRAV22 LOC105466239 LOC105466239 ENSMNEP00000033181 ENSMNEP00000033181 ALCAM ALCAM ENSMNEP00000032771 ENSMNEP00000032771 HLA-F HLA-F LSAMP LSAMP ENSMNEP00000031827 ENSMNEP00000031827 CD40LG CD40LG ICAM2 ICAM2 CLDN10 CLDN10 NECTIN2 NECTIN2 NCAM1 NCAM1 CD2 CD2 HLA-DQA1 HLA-DQA1 TRAC TRAC CLDN18 CLDN18 ENSMNEP00000029248 ENSMNEP00000029248 NLGN4Y NLGN4Y CLDN3 CLDN3 CLDN4 CLDN4 ENSMNEP00000028604 ENSMNEP00000028604 JAM2 JAM2 ITGB8 ITGB8 CDH3 CDH3 PECAM1 PECAM1 GLG1 GLG1 CLDN8 CLDN8 SDC1 SDC1 LRRC4 LRRC4 NLGN1 NLGN1 CD276 CD276 VCAN VCAN PTPRD PTPRD SELPLG SELPLG TIGIT TIGIT MANE-E MANE-E CNTN2 CNTN2 MR1 MR1 ENSMNEP00000025089 ENSMNEP00000025089 IGSF11 IGSF11 OCLN OCLN PTPRF PTPRF ENSMNEP00000023924 ENSMNEP00000023924 CNTN3 CNTN3 CLDN1 CLDN1 LOC105469851 LOC105469851 F11R F11R VCAM1 VCAM1 CLDN11 CLDN11 PTPRS PTPRS JAM3 JAM3 CLDN19 CLDN19 HHLA2 HHLA2 PDCD1 PDCD1 MANE-A MANE-A CADM3 CADM3 SDC2 SDC2 ACAN ACAN LOC105470432 LOC105470432 NCAM2 NCAM2 CD28 CD28 PTPRM PTPRM ENSMNEP00000019046 ENSMNEP00000019046 XG XG ENSMNEP00000018745 ENSMNEP00000018745 SELL SELL ICAM1 ICAM1 LOC105498909 LOC105498909 NTNG2 NTNG2 CD226 CD226 HLA-DMA HLA-DMA SELE SELE CD22 CD22 CD99 CD99 CNTNAP5 CNTNAP5 CD86 CD86 CDH15 CDH15 RTTN RTTN PVR PVR CNTNAP1 CNTNAP1 CD6 CD6 ITGB2 ITGB2 LRRC4B LRRC4B NFASC NFASC ENSMNEP00000013138 ENSMNEP00000013138 CEACAM19 CEACAM19 PTPRC PTPRC VSIR VSIR CLDN16 CLDN16 ESAM ESAM SDC3 SDC3 CD8B CD8B CD58 CD58 NECTIN3 NECTIN3 ITGB7 ITGB7 CADM2 CADM2 HLA-DPB1 HLA-DPB1 NCAN NCAN ICOSLG ICOSLG ENSMNEP00000010486 ENSMNEP00000010486 CLDN14 CLDN14 ICOS ICOS MPZ MPZ CNTNAP4 CNTNAP4 CLDN15 CLDN15 CHL1 CHL1 NTNG1 NTNG1 CD80 CD80 MADCAM1 MADCAM1 P3H3 P3H3 CD8A CD8A P3H1 P3H1 LOC105466472 LOC105466472 ENSMNEP00000007368 ENSMNEP00000007368 NLGN2 NLGN2 P3H2 P3H2 CLDN5 CLDN5 RIC1 RIC1 PDCD1LG2 PDCD1LG2 VASN VASN LOC105470433 LOC105470433 ENSMNEP00000004521 ENSMNEP00000004521 ITGB1 ITGB1 CDH4 CDH4 HLA-DRA HLA-DRA CNTN6 CNTN6 LRRC4C LRRC4C CLDN9 CLDN9 ITGAV ITGAV ENSMNEP00000002245 ENSMNEP00000002245 CD40 CD40 SPN SPN HLA-DOA HLA-DOA SIGLEC1 SIGLEC1 HLA-G HLA-G NRXN1 NRXN1 OPCML OPCML CLDN20 CLDN20 LOC105467297 LOC105467297 CLDN17 CLDN17 MANE-B MANE-B ITGA8 ITGA8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
NRCAMNeuronal cell adhesion molecule. (1304 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1027 aa)
ICAM3Intercellular adhesion molecule 3. (550 aa)
LOC105474426Ig-like domain-containing protein. (263 aa)
CNTN1Contactin 1. (1018 aa)
PTPRTProtein tyrosine phosphatase receptor type T. (1324 aa)
ENSMNEP00000043350Ig-like domain-containing protein. (233 aa)
LOC105474413Ig-like domain-containing protein. (295 aa)
CNTN4Contactin 4. (1010 aa)
MAGMyelin associated glycoprotein. (772 aa)
CD274CD274 molecule. (318 aa)
CNTN5Contactin 5. (1100 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
CTLA4CD152 protein. (223 aa)
NRXN2Neurexin 2. (1713 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (285 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1123 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
CADM1Cell adhesion molecule 1. (473 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
ENSMNEP00000040169Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
CD99L2CD99 molecule like 2. (261 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
L1CAML1 cell adhesion molecule. (1257 aa)
CLDN24Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
Mane-DRB1MHC class II protein. (266 aa)
ENSMNEP00000039202IGv domain-containing protein. (247 aa)
ENSMNEP00000038649Ig-like domain-containing protein. (235 aa)
TRBV27T cell receptor beta variable 27. (148 aa)
DNMT3LPHD-type domain-containing protein. (386 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
NEO1Neogenin 1. (1498 aa)
ENSMNEP00000037129Ig-like domain-containing protein. (346 aa)
NLGN3Neuroligin 3. (848 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1353 aa)
MPZL1Myelin protein zero like 1. (269 aa)
NRXN3Neurexin 3. (1664 aa)
CD34CD34 molecule. (385 aa)
NTMNeurotrimin. (355 aa)
SELPSelectin P. (830 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (194 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
GABPAGA binding protein transcription factor subunit alpha. (454 aa)
ENSMNEP00000035333Ig-like domain-containing protein; Belongs to the MHC class I family. (356 aa)
Mane-BIg-like domain-containing protein. (514 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1153 aa)
NECTIN1Nectin cell adhesion molecule 1. (519 aa)
AZGP1Alpha-2-glycoprotein 1, zinc-binding; Belongs to the MHC class I family. (298 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
TRAV22T cell receptor alpha variable 22. (147 aa)
LOC105466239Ig-like domain-containing protein; Belongs to the MHC class I family. (390 aa)
ENSMNEP00000033181Ig-like domain-containing protein; Belongs to the MHC class I family. (393 aa)
ALCAMActivated leukocyte cell adhesion molecule. (590 aa)
ENSMNEP00000032771LAM_G_DOMAIN domain-containing protein. (208 aa)
HLA-FMajor histocompatibility complex, class I, F; Belongs to the MHC class I family. (440 aa)
LSAMPLimbic system associated membrane protein. (345 aa)
ENSMNEP00000031827Ig-like domain-containing protein. (211 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa)
ICAM2Intercellular adhesion molecule 2. (275 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa)
NECTIN2Nectin cell adhesion molecule 2. (513 aa)
NCAM1Neural cell adhesion molecule 1. (1016 aa)
CD2CD2 molecule. (351 aa)
HLA-DQA1Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (267 aa)
TRACT cell receptor alpha constant. (110 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
ENSMNEP00000029248MHC_I-like_Ag-recog domain-containing protein. (172 aa)
NLGN4YNeuroligin 4 Y-linked. (873 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
ENSMNEP00000028604IGv domain-containing protein. (139 aa)
JAM2Junctional adhesion molecule 2. (311 aa)
ITGB8Integrin beta. (421 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (717 aa)
GLG1Golgi glycoprotein 1. (1042 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
LRRC4Leucine rich repeat containing 4. (633 aa)
NLGN1Neuroligin 1. (823 aa)
CD276CD276 molecule. (534 aa)
VCANVersican core protein; May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronan. (3398 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1912 aa)
SELPLGSelectin P ligand. (429 aa)
TIGITT cell immunoreceptor with Ig and ITIM domains. (312 aa)
MANE-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
CNTN2Contactin 2. (1040 aa)
MR1Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (385 aa)
ENSMNEP00000025089Ig-like domain-containing protein. (235 aa)
IGSF11Immunoglobulin superfamily member 11. (431 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1910 aa)
ENSMNEP00000023924MHC_I-like_Ag-recog domain-containing protein. (162 aa)
CNTN3Contactin 3. (1028 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
LOC105469851Ig-like domain-containing protein; Belongs to the MHC class I family. (381 aa)
F11RF11 receptor. (328 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1911 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
HHLA2HERV-H LTR-associating 2. (426 aa)
PDCD1Programmed cell death 1. (288 aa)
MANE-AMHC_I-like_Ag-recog domain-containing protein. (116 aa)
CADM3Cell adhesion molecule 3. (430 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
ACANAggrecan. (2214 aa)
LOC105470432Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa)
NCAM2Neural cell adhesion molecule 2. (837 aa)
CD28CD28 molecule. (220 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1465 aa)
ENSMNEP00000019046Uncharacterized protein. (39 aa)
XGXg glycoprotein (Xg blood group). (193 aa)
ENSMNEP00000018745Ig-like domain-containing protein; Belongs to the MHC class I family. (317 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (385 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
LOC105498909Uncharacterized protein. (1281 aa)
NTNG2Netrin G2. (530 aa)
CD226CD226 molecule. (316 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa)
SELESelectin E. (612 aa)
CD22CD22 molecule. (848 aa)
CD99CD99 molecule (Xg blood group). (182 aa)
CNTNAP5Contactin associated protein like 5. (1306 aa)
CD86CD86 molecule. (329 aa)
CDH15Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (813 aa)
RTTNRotatin. (2232 aa)
PVRPVR cell adhesion molecule. (417 aa)
CNTNAP1Contactin associated protein 1. (1382 aa)
CD6CD6 molecule. (699 aa)
ITGB2Integrin beta. (921 aa)
LRRC4BLeucine rich repeat containing 4B. (713 aa)
NFASCNeurofascin. (1357 aa)
ENSMNEP00000013138Ig-like domain-containing protein; Belongs to the MHC class I family. (352 aa)
CEACAM19Carcinoembryonic antigen related cell adhesion molecule 19. (300 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
VSIRV-set immunoregulatory receptor. (311 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
ESAMEndothelial cell adhesion molecule. (392 aa)
SDC3Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (440 aa)
CD8BIg-like domain-containing protein. (243 aa)
CD58CD58 molecule. (250 aa)
NECTIN3Nectin cell adhesion molecule 3. (548 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
CADM2Cell adhesion molecule 2. (437 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (268 aa)
NCANNeurocan. (1320 aa)
ICOSLGUncharacterized protein. (302 aa)
ENSMNEP00000010486Ig-like domain-containing protein. (133 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (248 aa)
ICOSInducible T cell costimulator. (199 aa)
MPZMyelin protein zero. (256 aa)
CNTNAP4Uncharacterized protein. (1308 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (228 aa)
CHL1Cell adhesion molecule L1 like. (1225 aa)
NTNG1Netrin G1. (539 aa)
CD80CD80 molecule. (288 aa)
MADCAM1Mucosal vascular addressin cell adhesion molecule 1. (384 aa)
P3H3Prolyl 3-hydroxylase 3. (735 aa)
CD8ACD8a molecule. (253 aa)
P3H1Prolyl 3-hydroxylase 1. (797 aa)
LOC105466472Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa)
ENSMNEP00000007368MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (168 aa)
NLGN2Neuroligin 2. (849 aa)
P3H2Prolyl 3-hydroxylase 2. (705 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
RIC1RIC1 homolog, RAB6A GEF complex partner 1. (1343 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)
VASNVasorin. (673 aa)
LOC105470433MHC class II antigen. (260 aa)
ENSMNEP00000004521Ig-like domain-containing protein. (230 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
CDH4Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (916 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
CNTN6Contactin 6. (1029 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1017 aa)
ENSMNEP00000002245Ig-like domain-containing protein. (232 aa)
CD40CD40 molecule. (278 aa)
SPNSialophorin. (405 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
SIGLEC1Sialic acid binding Ig like lectin 1. (1709 aa)
HLA-GIGc1 domain-containing protein; Belongs to the MHC class I family. (354 aa)
NRXN1Neurexin 1. (1507 aa)
OPCMLOpioid binding protein/cell adhesion molecule like. (345 aa)
CLDN20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
LOC105467297Ig-like domain-containing protein; Belongs to the MHC class I family. (242 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
MANE-BIg-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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