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| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (532 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) |
| | STING1 | Transmembrane protein 173. (379 aa) |
| | RNF31 | Uncharacterized protein. (1078 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa) |
| | PRKCD | Protein kinase C. (729 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1926 aa) |
| | LOC105475002 | AIG1-type G domain-containing protein. (307 aa) |
| | MCU | Mitochondrial calcium uniporter. (351 aa) |
| | CCL2 | C-C motif chemokine. (99 aa) |
| | TYK2 | Tyrosine-protein kinase. (1190 aa) |
| | ENSMNEP00000030762 | GB1/RHD3-type G domain-containing protein. (602 aa) |
| | ANTXRL | VWFA domain-containing protein. (591 aa) |
| | ENSMNEP00000030379 | MPN domain-containing protein. (285 aa) |
| | IFI16 | Interferon gamma inducible protein 16. (729 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | FCHO2 | FCH domain only 2. (815 aa) |
| | RNH1 | Ribonuclease/angiogenin inhibitor 1. (456 aa) |
| | ARRDC4 | Arrestin domain containing 4. (418 aa) |
| | PSTPIP2 | Proline-serine-threonine phosphatase interacting protein 2. (334 aa) |
| | TICAM1 | Toll like receptor adaptor molecule 1. (519 aa) |
| | LOC105498418 | Uncharacterized protein. (190 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | ARHGEF17 | Rho guanine nucleotide exchange factor 17. (2068 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | TXNDC8 | Thioredoxin domain containing 8. (127 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | GAS7 | Growth arrest specific 7. (476 aa) |
| | MEFV | MEFV innate immuity regulator, pyrin. (786 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa) |
| | IRF3 | Interferon regulatory factor 3. (422 aa) |
| | TXN2 | Thioredoxin 2. (182 aa) |
| | RHOC | Ras homolog family member C. (193 aa) |
| | XIAP | X-linked inhibitor of apoptosis. (497 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1866 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (790 aa) |
| | ATL2 | Atlastin GTPase 2. (565 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1375 aa) |
| | CASP5 | Caspase 5; Belongs to the peptidase C14A family. (462 aa) |
| | CASR | Calcium sensing receptor. (1078 aa) |
| | MNDA | Myeloid cell nuclear differentiation antigen. (407 aa) |
| | TXNDC2 | Thioredoxin domain containing 2. (433 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa) |
| | GBP3 | Guanylate binding protein 3. (595 aa) |
| | NLRP12 | NLR family pyrin domain containing 12. (973 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | CEP78 | Centrosomal protein 78. (801 aa) |
| | GPRC6A | G protein-coupled receptor class C group 6 member A. (928 aa) |
| | ENSMNEP00000023427 | Uncharacterized protein. (198 aa) |
| | ARRDC1 | Arrestin domain containing 1. (440 aa) |
| | PANX1 | Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa) |
| | NLRP9 | NLR family pyrin domain containing 9. (881 aa) |
| | DHX33 | DEAH-box helicase 33. (680 aa) |
| | CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | OTUD7B | OTU deubiquitinase 7B. (843 aa) |
| | ATL3 | Atlastin GTPase 3. (544 aa) |
| | HSP90AA1 | Heat shock protein 90 alpha family class A member 1. (823 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | TRPM7 | Transient receptor potential cation channel subfamily M member 7. (1849 aa) |
| | CARD8 | Uncharacterized protein. (424 aa) |
| | HSP90AB1 | Heat shock protein 90 alpha family class B member 1. (724 aa) |
| | PKN2 | Protein kinase N2. (983 aa) |
| | FCHO1 | FCH domain only 1. (872 aa) |
| | STAT2 | Signal transducer and activator of transcription. (852 aa) |
| | NEK6 | NIMA related kinase 6; Belongs to the protein kinase superfamily. (347 aa) |
| | PYDC1 | Pyrin domain containing 1. (88 aa) |
| | NLRP1 | NLR family pyrin domain containing 1. (1456 aa) |
| | ARHGEF33 | Rho guanine nucleotide exchange factor 33. (917 aa) |
| | ENSMNEP00000019155 | Interfer-bind domain-containing protein. (338 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa) |
| | DEFA6 | Defensin alpha 6. (100 aa) |
| | ARRDC3 | Arrestin domain containing 3. (414 aa) |
| | BRCC3 | MPN domain-containing protein. (297 aa) |
| | ENSMNEP00000018013 | Uncharacterized protein. (243 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | GBP7 | Guanylate binding protein 7. (647 aa) |
| | RNASEL | Ribonuclease L. (741 aa) |
| | CARD6 | Caspase recruitment domain family member 6. (1037 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1044 aa) |
| | NME9 | NME/NM23 family member 9; Belongs to the NDK family. (330 aa) |
| | CASP12 | Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (408 aa) |
| | ENSMNEP00000016333 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (190 aa) |
| | CXCL1 | C-X-C motif chemokine. (107 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | ENSMNEP00000015675 | Uncharacterized protein. (105 aa) |
| | NLRP2 | NLR family pyrin domain containing 2. (1039 aa) |
| | ARIH1 | Ariadne RBR E3 ubiquitin protein ligase 1. (483 aa) |
| | ENSMNEP00000015253 | HATPase_c domain-containing protein. (688 aa) |
| | LOC105477292 | C-X-C motif chemokine. (154 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (488 aa) |
| | IRF9 | Interferon regulatory factor 9. (392 aa) |
| | NAMPT | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (492 aa) |
| | ENSMNEP00000014831 | HATPase_c domain-containing protein. (645 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | GSDMD | Gasdermin D. (523 aa) |
| | LOC105468980 | DEFENSIN domain-containing protein. (94 aa) |
| | GIMAP7 | GTPase, IMAP family member 7. (279 aa) |
| | LOC105464162 | Defensin_propep domain-containing protein; Belongs to the alpha-defensin family. (76 aa) |
| | RNF217 | RBR-type E3 ubiquitin transferase. (542 aa) |
| | ENSMNEP00000013313 | Uncharacterized protein. (152 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (687 aa) |
| | SGIP1 | SH3 domain GRB2 like endophilin interacting protein 1. (859 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (535 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | AIM2 | Absent in melanoma 2. (343 aa) |
| | RNF19A | RBR-type E3 ubiquitin transferase. (838 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | RNF144A | RBR-type E3 ubiquitin transferase. (292 aa) |
| | NAIP | NLR family apoptosis inhibitory protein. (1356 aa) |
| | PYHIN1 | Pyrin and HIN domain family member 1. (494 aa) |
| | ENSMNEP00000012002 | TNF receptor-associated factor. (457 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa) |
| | ENSMNEP00000011844 | Uncharacterized protein. (424 aa) |
| | LOC105464163 | Defensin_propep domain-containing protein; Belongs to the alpha-defensin family. (76 aa) |
| | LOC105471157 | C-X-C motif chemokine. (103 aa) |
| | ZRANB1 | Zinc finger RANBP2-type containing 1. (734 aa) |
| | ATG16L1 | Autophagy related 16 like 1. (624 aa) |
| | CUL9 | Cullin 9; Belongs to the cullin family. (2517 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (968 aa) |
| | PSTPIP1 | Proline-serine-threonine phosphatase interacting protein 1. (416 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (693 aa) |
| | GIMAP6 | GTPase, IMAP family member 6. (361 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (1044 aa) |
| | GIMAP2 | GTPase, IMAP family member 2. (340 aa) |
| | ENSMNEP00000010044 | DEFENSIN domain-containing protein. (81 aa) |
| | SUGT1 | SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (365 aa) |
| | ANTXR2 | Anthrax toxin receptor; Belongs to the ATR family. (488 aa) |
| | CTSB | Cathepsin B; Belongs to the peptidase C1 family. (339 aa) |
| | TRPV2 | Transient receptor potential cation channel subfamily V member 2. (718 aa) |
| | IRF7 | Interferon regulatory factor 7. (504 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa) |
| | ENSMNEP00000008684 | Uncharacterized protein. (389 aa) |
| | LOC105474889 | AIG1-type G domain-containing protein. (307 aa) |
| | GIMAP4 | GTPase, IMAP family member 4. (329 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1174 aa) |
| | ANKIB1 | RBR-type E3 ubiquitin transferase. (1089 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | ENSMNEP00000007520 | CARD domain-containing protein. (359 aa) |
| | TRIM14 | Tripartite motif containing 14. (442 aa) |
| | ENSMNEP00000006959 | Uncharacterized protein. (262 aa) |
| | TRPM2 | Transient receptor potential cation channel subfamily M member 2. (1556 aa) |
| | RNF144B | RBR-type E3 ubiquitin transferase. (303 aa) |
| | CASP4 | Caspase 4; Belongs to the peptidase C14A family. (377 aa) |
| | CYBB | Cytochrome b-245 beta chain. (614 aa) |
| | NLRP10 | NLR family pyrin domain containing 10. (663 aa) |
| | ENSMNEP00000005419 | Uncharacterized protein. (114 aa) |
| | PYDC2 | Pyrin domain containing 2. (139 aa) |
| | ERBIN | Erbb2 interacting protein. (1418 aa) |
| | LOC105464161 | DEFENSIN domain-containing protein. (96 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | VCPIP1 | Valosin containing protein interacting protein 1. (1221 aa) |
| | LOC105499846 | Uncharacterized protein. (67 aa) |
| | GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) |
| | PKN1 | Protein kinase N1. (949 aa) |
| | LOC105499844 | DEFSN domain-containing protein. (64 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | VDAC1 | Uncharacterized protein. (321 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | ENSMNEP00000002263 | Uncharacterized protein. (329 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (541 aa) |
| | TANK | TRAF family member associated NFKB activator. (425 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (442 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | URGCP | Upregulator of cell proliferation. (934 aa) |
| | ENSMNEP00000001281 | VWFA domain-containing protein. (530 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | LRRC34 | Leucine rich repeat containing 34. (389 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | OTUD7A | OTU deubiquitinase 7A. (906 aa) |
| | LRRC71 | Leucine rich repeat containing 71. (559 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (487 aa) |
| | ENSMNEP00000033022 | Uncharacterized protein. (77 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | TRIP6 | Thyroid hormone receptor interactor 6. (476 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | LRRC31 | Leucine rich repeat containing 31. (552 aa) |
| | NLRX1 | NLR family member X1. (972 aa) |
| | CYBA | Cytochrome b-245 alpha chain. (197 aa) |
| | LRRC7 | Leucine rich repeat containing 7. (1542 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | GABARAPL1 | GABA type A receptor associated protein like 1. (146 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa) |
| | MFN1 | Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (688 aa) |
| | NLRP13 | NLR family pyrin domain containing 13. (1030 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | MAPK9 | Mitogen-activated protein kinase 9. (354 aa) |
| | IFNAR2 | Uncharacterized protein. (516 aa) |
| | IFNA14 | Interferon alpha 14. (137 aa) |
| | CARD18 | Caspase recruitment domain family member 18. (92 aa) |
| | XKRX | XK-related protein. (449 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | ENSMNEP00000038155 | Uncharacterized protein. (314 aa) |
| | GIMAP8 | GTPase, IMAP family member 8. (665 aa) |
| | LOC105478630 | Uncharacterized protein. (479 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | NLRP7 | NLR family pyrin domain containing 7. (981 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | RNF19B | RBR-type E3 ubiquitin transferase. (541 aa) |
| | ENSMNEP00000039751 | Uncharacterized protein. (123 aa) |
| | TXNIP | Thioredoxin interacting protein. (391 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | ANTXR1 | ANTXR cell adhesion molecule 1. (589 aa) |
| | ATL1 | Atlastin GTPase 1. (558 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | ARHGEF10L | Rho guanine nucleotide exchange factor 10 like. (1277 aa) |
| | ARRDC5 | Arrestin domain containing 5. (294 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (489 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (496 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | NLRP14 | NLR family pyrin domain containing 14. (1092 aa) |
| | ARRDC2 | Arrestin domain containing 2. (417 aa) |
| | LOC105498430 | Uncharacterized protein. (189 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1035 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (308 aa) |
| | LPP | LIM domain containing preferred translocation partner in lipoma. (613 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
| | TXN | Thioredoxin; Belongs to the thioredoxin family. (105 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (488 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1076 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | NFKBIB | NFKB inhibitor beta. (356 aa) |
| | MFN2 | Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa) |
| | MCUB | Mitochondrial calcium uniporter dominant negative beta subunit. (336 aa) |
| | ENSMNEP00000044641 | Uncharacterized protein. (111 aa) |
| | GIMAP1 | AIG1-type G domain-containing protein. (306 aa) |
| | CAMP | Cathelicidin antimicrobial peptide. (173 aa) |
| | NLRC3 | NLR family CARD domain containing 3. (1174 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | LOC105493689 | Uncharacterized protein; Belongs to the peptidase C14A family. (410 aa) |
| | NUGGC | Nuclear GTPase, germinal center associated. (796 aa) |
| | ENSMNEP00000001232 | Uncharacterized protein. (117 aa) |
| | STAT1 | Signal transducer and activator of transcription. (758 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | ARHGEF10 | Rho guanine nucleotide exchange factor 10. (1345 aa) |
| | SHARPIN | SHANK associated RH domain interactor. (382 aa) |
| | IL6 | Interleukin 6. (214 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa) |
| | LOC105468981 | DEFENSIN domain-containing protein. (93 aa) |
