Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKT1 | AKT2 | ENSMNEP00000026038 | ENSMNEP00000028923 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.975 |
| AKT1 | AKT3 | ENSMNEP00000026038 | ENSMNEP00000038984 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.932 |
| AKT1 | BCL2 | ENSMNEP00000026038 | ENSMNEP00000023608 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | BCL2 apoptosis regulator. | 0.957 |
| AKT1 | BCL2L1 | ENSMNEP00000026038 | ENSMNEP00000002756 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | BCL2 like 1. | 0.957 |
| AKT1 | CCND1 | ENSMNEP00000026038 | ENSMNEP00000035178 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Cyclin D1; Belongs to the cyclin family. | 0.537 |
| AKT1 | CDKN1A | ENSMNEP00000026038 | ENSMNEP00000002098 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Cyclin dependent kinase inhibitor 1A. | 0.977 |
| AKT1 | CREBBP | ENSMNEP00000026038 | ENSMNEP00000041109 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | CREB binding protein. | 0.465 |
| AKT1 | EGF | ENSMNEP00000026038 | ENSMNEP00000019342 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | 0.529 |
| AKT1 | EGFR | ENSMNEP00000026038 | ENSMNEP00000005295 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Receptor protein-tyrosine kinase. | 0.418 |
| AKT1 | EP300 | ENSMNEP00000026038 | ENSMNEP00000040649 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | E1A binding protein p300. | 0.781 |
| AKT1 | GRB2 | ENSMNEP00000026038 | ENSMNEP00000026946 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Growth factor receptor bound protein 2. | 0.566 |
| AKT1 | HRAS | ENSMNEP00000026038 | ENSMNEP00000031954 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | HRas proto-oncogene, GTPase. | 0.564 |
| AKT1 | IFNG | ENSMNEP00000026038 | ENSMNEP00000045088 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.415 |
| AKT1 | IL10 | ENSMNEP00000026038 | ENSMNEP00000036763 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.403 |
| AKT1 | IL4 | ENSMNEP00000026038 | ENSMNEP00000020267 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. | 0.563 |
| AKT1 | IL6 | ENSMNEP00000026038 | ENSMNEP00000000727 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Interleukin 6. | 0.502 |
| AKT1 | JAK2 | ENSMNEP00000026038 | ENSMNEP00000014154 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Tyrosine-protein kinase. | 0.482 |
| AKT1 | LEP | ENSMNEP00000026038 | ENSMNEP00000022271 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.494 |
| AKT1 | MCL1 | ENSMNEP00000026038 | ENSMNEP00000045951 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | MCL1 apoptosis regulator, BCL2 family member. | 0.459 |
| AKT1 | MTOR | ENSMNEP00000026038 | ENSMNEP00000010030 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. | 0.993 |
page 1 of 319