STRINGSTRING
CSF3 CSF3 ELAVL1 ELAVL1 ENSMNEP00000008684 ENSMNEP00000008684 CCL11 CCL11 LOC105477295 LOC105477295 S100A7A S100A7A NFKB1 NFKB1 LOC105471157 LOC105471157 MAPK1 MAPK1 MAPK11 MAPK11 ENSMNEP00000012002 ENSMNEP00000012002 CHUK CHUK MAPK8 MAPK8 ENSMNEP00000014831 ENSMNEP00000014831 TRAF3IP2 TRAF3IP2 FOS FOS LOC105477292 LOC105477292 ENSMNEP00000015253 ENSMNEP00000015253 MAPK3 MAPK3 CXCL1 CXCL1 ENSMNEP00000017745 ENSMNEP00000017745 CCL17 CCL17 LOC105477289 LOC105477289 PTGS2 PTGS2 MAPK15 MAPK15 IL17D IL17D S100A9 S100A9 HSP90B1 HSP90B1 IL4 IL4 HSP90AB1 HSP90AB1 HSP90AA1 HSP90AA1 MMP1 MMP1 CXCL8 CXCL8 MMP9 MMP9 IL17C IL17C CXCL6 CXCL6 CCL7 CCL7 TNFAIP3 TNFAIP3 IL17RA IL17RA MAPK6 MAPK6 ANAPC5 ANAPC5 CSF2 CSF2 MAP3K7 MAP3K7 NFKBIA NFKBIA CASP8 CASP8 IL1B IL1B IKBKB IKBKB IL17RB IL17RB MAPK13 MAPK13 IL17A IL17A MAPK7 MAPK7 MAPK9 MAPK9 IKBKE IKBKE CCL20 CCL20 LCN2 LCN2 ENSMNEP00000038155 ENSMNEP00000038155 TRAF6 TRAF6 S100A8 S100A8 MAPK12 MAPK12 IL17RC IL17RC MAPK10 MAPK10 TBK1 TBK1 MMP3 MMP3 IL25 IL25 RELA RELA MMP13 MMP13 IL17RE IL17RE FADD FADD TNF TNF TRAF4 TRAF4 TAB3 TAB3 MAPK4 MAPK4 IL17F IL17F CCL2 CCL2 FOSB FOSB TRAF5 TRAF5 SRSF1 SRSF1 S100A7L2 S100A7L2 GSK3B GSK3B MMP10 MMP10 LOC105492342 LOC105492342 IL13 IL13 TRAF2 TRAF2 ENSMNEP00000004019 ENSMNEP00000004019 TRADD TRADD LOC105499844 LOC105499844 TAB2 TAB2 ENSMNEP00000003449 ENSMNEP00000003449 ENSMNEP00000002118 ENSMNEP00000002118 IL5 IL5 CEBPB CEBPB TRAF3 TRAF3 ENSMNEP00000001232 ENSMNEP00000001232 IL6 IL6 IL17B IL17B IKBKG IKBKG FOSL1 FOSL1 USP25 USP25 ENSMNEP00000041867 ENSMNEP00000041867 MUC5B MUC5B ENSMNEP00000043781 ENSMNEP00000043781 IFNG IFNG MAPK14 MAPK14 CXCL10 CXCL10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSF3Colony stimulating factor 3. (207 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
ENSMNEP00000008684Uncharacterized protein. (389 aa)
CCL11C-C motif chemokine. (97 aa)
LOC105477295C-X-C motif chemokine. (114 aa)
S100A7AProtein S100; Belongs to the S-100 family. (101 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
LOC105471157C-X-C motif chemokine. (103 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
ENSMNEP00000012002TNF receptor-associated factor. (457 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSMNEP00000014831HATPase_c domain-containing protein. (645 aa)
TRAF3IP2TRAF3 interacting protein 2. (570 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
LOC105477292C-X-C motif chemokine. (154 aa)
ENSMNEP00000015253HATPase_c domain-containing protein. (688 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CXCL1C-X-C motif chemokine. (107 aa)
ENSMNEP00000017745Uncharacterized protein. (58 aa)
CCL17C-C motif chemokine. (91 aa)
LOC105477289C-X-C motif chemokine. (114 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
IL17DInterleukin 17D. (202 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
HSP90B1Heat shock protein 90 beta family member 1. (804 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (823 aa)
MMP1Matrix metallopeptidase 1. (469 aa)
CXCL8Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
MMP9Matrix metallopeptidase 9. (694 aa)
IL17CInterleukin 17C. (197 aa)
CXCL6C-X-C motif chemokine. (123 aa)
CCL7C-C motif chemokine. (105 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
IL17RAInterleukin 17 receptor A. (865 aa)
MAPK6Mitogen-activated protein kinase 6. (721 aa)
ANAPC5Anaphase promoting complex subunit 5. (691 aa)
CSF2Colony stimulating factor 2. (144 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (487 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
IL17RBInterleukin 17 receptor B. (502 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
IL17AInterleukin 17A. (155 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (813 aa)
MAPK9Mitogen-activated protein kinase 9. (354 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
CCL20C-C motif chemokine. (96 aa)
LCN2Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (212 aa)
ENSMNEP00000038155Uncharacterized protein. (314 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
IL17RCInterleukin 17 receptor C. (787 aa)
MAPK10Mitogen-activated protein kinase. (489 aa)
TBK1TANK binding kinase 1. (729 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
IL25Interleukin 25. (160 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
MMP13Matrix metallopeptidase 13. (503 aa)
IL17REInterleukin 17 receptor E. (696 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
TRAF4TNF receptor-associated factor. (470 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
MAPK4Mitogen-activated protein kinase 4. (587 aa)
IL17FInterleukin 17F. (163 aa)
CCL2C-C motif chemokine. (99 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (302 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
SRSF1Uncharacterized protein. (253 aa)
S100A7L2S100 calcium binding protein A7 like 2. (107 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
MMP10Matrix metallopeptidase 10. (475 aa)
LOC105492342Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
IL13Interleukin 13. (146 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (532 aa)
ENSMNEP00000004019Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
LOC105499844DEFSN domain-containing protein. (64 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
ENSMNEP00000003449Uncharacterized protein. (253 aa)
ENSMNEP00000002118Uncharacterized protein. (381 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
CEBPBCCAAT/enhancer-binding protein. (344 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
ENSMNEP00000001232Uncharacterized protein. (117 aa)
IL6Interleukin 6. (214 aa)
IL17BInterleukin 17B. (180 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
USP25Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1125 aa)
ENSMNEP00000041867Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa)
MUC5BMucin 5B, oligomeric mucus/gel-forming. (4260 aa)
ENSMNEP00000043781Protein kinase domain-containing protein. (601 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CXCL10C-X-C motif chemokine 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (98 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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