STRINGSTRING
FCGR1A FCGR1A MARCKS MARCKS PIK3CB PIK3CB ENSMNEP00000000821 ENSMNEP00000000821 ENSMNEP00000001351 ENSMNEP00000001351 PIP5K1B PIP5K1B PLCG2 PLCG2 PIP5K1A PIP5K1A PLD1 PLD1 SPHK1 SPHK1 ASAP2 ASAP2 PLA2G4D PLA2G4D ENSMNEP00000004647 ENSMNEP00000004647 ARPC5L ARPC5L PIP5K1C PIP5K1C PRKCB PRKCB MAP2K1 MAP2K1 ENSMNEP00000006433 ENSMNEP00000006433 BIN1 BIN1 INPP5D INPP5D PIK3R2 PIK3R2 WASF3 WASF3 ENSMNEP00000009016 ENSMNEP00000009016 VAV3 VAV3 DNM2 DNM2 WASF1 WASF1 ENSMNEP00000010506 ENSMNEP00000010506 PLA2G4C PLA2G4C ENSMNEP00000011554 ENSMNEP00000011554 MAPK1 MAPK1 ASAP3 ASAP3 PTPRC PTPRC JMJD7 JMJD7 GOLGA2 GOLGA2 PLA2G4F PLA2G4F VASP VASP INPPL1 INPPL1 ENSMNEP00000015467 ENSMNEP00000015467 MAPK3 MAPK3 RPS6KB2 RPS6KB2 PRKCE PRKCE ENSMNEP00000016854 ENSMNEP00000016854 ASAP1 ASAP1 AMPH AMPH PLD2 PLD2 PLA2G4E PLA2G4E NCF1 NCF1 ARPC1B ARPC1B RAC2 RAC2 WASF2 WASF2 CRKL CRKL VAV1 VAV1 CFL1 CFL1 PIK3CA PIK3CA CCDC125 CCDC125 ENSMNEP00000020833 ENSMNEP00000020833 WAS WAS CDC42 CDC42 ENSMNEP00000021191 ENSMNEP00000021191 ENSMNEP00000021289 ENSMNEP00000021289 DOCK1 DOCK1 LOC105490998 LOC105490998 ENSMNEP00000022491 ENSMNEP00000022491 LAT LAT ARPC2 ARPC2 ARF6 ARF6 FCGR2B FCGR2B VAV2 VAV2 ENSMNEP00000024309 ENSMNEP00000024309 GAB4 GAB4 PLA2G6 PLA2G6 ENSMNEP00000025520 ENSMNEP00000025520 PLPP2 PLPP2 LIMK2 LIMK2 AKT1 AKT1 LOC105479412 LOC105479412 ENSMNEP00000027902 ENSMNEP00000027902 SYK SYK PRKCA PRKCA PRKCG PRKCG AKT2 AKT2 ENSMNEP00000029022 ENSMNEP00000029022 GSN GSN PIK3R1 PIK3R1 ENSMNEP00000030807 ENSMNEP00000030807 PIK3CD PIK3CD RAC1 RAC1 PRKCD PRKCD PLA2G4A PLA2G4A CFL2 CFL2 LOC105498220 LOC105498220 PLPP3 PLPP3 CRK CRK ENSMNEP00000032785 ENSMNEP00000032785 ENSMNEP00000032949 ENSMNEP00000032949 SPHK2 SPHK2 RAF1 RAF1 GAB2 GAB2 LIMK1 LIMK1 ENSMNEP00000037329 ENSMNEP00000037329 PLPP1 PLPP1 LYN LYN SCIN SCIN HCK HCK PIK3R3 PIK3R3 AKT3 AKT3 PLCG1 PLCG1 ENSMNEP00000041202 ENSMNEP00000041202 MYO10 MYO10 ENSMNEP00000043922 ENSMNEP00000043922 PAK1 PAK1 MARCKSL1 MARCKSL1 ENSMNEP00000045127 ENSMNEP00000045127 RPS6KB1 RPS6KB1 ARPC5 ARPC5 ARPC4 ARPC4 ARPC1A ARPC1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FCGR1AUncharacterized protein. (357 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (331 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
ENSMNEP00000000821Ig-like domain-containing protein. (143 aa)
ENSMNEP00000001351Ig-like domain-containing protein. (151 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (554 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (612 aa)
PLD1Phospholipase. (1074 aa)
SPHK1Sphingosine kinase 1. (470 aa)
ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (1006 aa)
PLA2G4DPhospholipase A2. (822 aa)
ENSMNEP00000004647Uncharacterized protein. (185 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (159 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (705 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (361 aa)
ENSMNEP00000006433Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa)
BIN1Bridging integrator 1. (608 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1203 aa)
PIK3R2Uncharacterized protein. (668 aa)
WASF3WASP family member 3. (502 aa)
ENSMNEP00000009016Uncharacterized protein. (345 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
WASF1WASP family member 1. (559 aa)
ENSMNEP00000010506Ig-like domain-containing protein. (142 aa)
PLA2G4CPhospholipase A2 group IVC. (535 aa)
ENSMNEP00000011554Uncharacterized protein. (157 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (903 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
JMJD7Jumonji domain containing 7. (364 aa)
GOLGA2Golgin A2. (1033 aa)
PLA2G4FPhospholipase A2. (849 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1333 aa)
ENSMNEP00000015467Uncharacterized protein. (312 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
ENSMNEP00000016854ADF-H domain-containing protein. (135 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1062 aa)
AMPHAmphiphysin. (694 aa)
PLD2Phospholipase. (933 aa)
PLA2G4EPhospholipase A2. (869 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (375 aa)
RAC2Rac family small GTPase 2. (192 aa)
WASF2WASP family member 2. (499 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (196 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CCDC125Coiled-coil domain containing 125. (510 aa)
ENSMNEP00000020833Ig-like domain-containing protein. (145 aa)
WASWASP actin nucleation promoting factor. (545 aa)
CDC42Uncharacterized protein. (191 aa)
ENSMNEP00000021191Uncharacterized protein. (583 aa)
ENSMNEP00000021289Ig-like domain-containing protein. (182 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
LOC105490998Uncharacterized protein. (441 aa)
ENSMNEP00000022491Uncharacterized protein. (528 aa)
LATLinker for activation of T cells. (271 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
FCGR2BUncharacterized protein. (313 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
ENSMNEP00000024309Uncharacterized protein. (622 aa)
GAB4GRB2 associated binding protein family member 4. (533 aa)
PLA2G6Phospholipase A2 group VI. (836 aa)
ENSMNEP00000025520Ig-like domain-containing protein. (194 aa)
PLPP2Phospholipid phosphatase 2. (302 aa)
LIMK2LIM domain kinase 2. (638 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC105479412Uncharacterized protein. (650 aa)
ENSMNEP00000027902Protein kinase domain-containing protein. (365 aa)
SYKTyrosine-protein kinase. (629 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSMNEP00000029022Uncharacterized protein. (185 aa)
GSNGelsolin. (759 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSMNEP00000030807Uncharacterized protein. (120 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
RAC1Rac family small GTPase 1. (211 aa)
PRKCDProtein kinase C. (729 aa)
PLA2G4APhospholipase A2. (749 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
LOC105498220Uncharacterized protein. (342 aa)
PLPP3acidPPc domain-containing protein. (353 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
ENSMNEP00000032785PIPK domain-containing protein. (470 aa)
ENSMNEP00000032949Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (164 aa)
SPHK2Sphingosine kinase 2. (653 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
GAB2GRB2 associated binding protein 2. (677 aa)
LIMK1LIM domain kinase 1. (677 aa)
ENSMNEP00000037329Phospholipase A2. (781 aa)
PLPP1Phospholipid phosphatase 1. (284 aa)
LYNTyrosine-protein kinase. (512 aa)
SCINScinderin. (715 aa)
HCKTyrosine-protein kinase. (504 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (463 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
ENSMNEP00000041202ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (209 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2019 aa)
ENSMNEP00000043922Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (133 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
MARCKSL1MARCKS like 1. (195 aa)
ENSMNEP00000045127Uncharacterized protein. (183 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ARPC4Uncharacterized protein. (78 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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