STRINGSTRING
CALM1 CALM1 CAMK2D CAMK2D ADCY3 ADCY3 ADCY2 ADCY2 GNAO1 GNAO1 PLCB1 PLCB1 KCNJ9 KCNJ9 GNG4 GNG4 GNG12 GNG12 CAMK2A CAMK2A GRIN2D GRIN2D GNGT1 GNGT1 ADCY5 ADCY5 ADCY6 ADCY6 PRKACA PRKACA ADCYAP1R1 ADCYAP1R1 KCNJ3 KCNJ3 GNG14 GNG14 GNG13 GNG13 ADCY4 ADCY4 CAMK2G CAMK2G GNG3 GNG3 GNB5 GNB5 CACNA1D CACNA1D ENSMNEP00000034688 ENSMNEP00000034688 GRIA1 GRIA1 ADCY8 ADCY8 GRIA4 GRIA4 ARSI ARSI CAMK2B CAMK2B CACNA1G CACNA1G PRKACB PRKACB GNAI1 GNAI1 GRIN2A GRIN2A CALM3 CALM3 RPS6KA5 RPS6KA5 PRKCG PRKCG PRKCA PRKCA PER1 PER1 GNG5 GNG5 CALM2 CALM2 KCNJ6 KCNJ6 ITPR3 ITPR3 GNB3 GNB3 FBXO21 FBXO21 GUCY1A1 GUCY1A1 ENSMNEP00000025595 ENSMNEP00000025595 CACNA1H CACNA1H GNB1 GNB1 NOS1AP NOS1AP NOS1 NOS1 ADCY10 ADCY10 GNAI3 GNAI3 CALML6 CALML6 PVALEF PVALEF ITPR1 ITPR1 PTRHD1 PTRHD1 RYR1 RYR1 GNAS GNAS GNAI2 GNAI2 ADCYAP1 ADCYAP1 LOC105490737 LOC105490737 CACNA1I CACNA1I CALML4 CALML4 GRIA3 GRIA3 PRKG1 PRKG1 ENSMNEP00000016414 ENSMNEP00000016414 RYR3 RYR3 MAPK3 MAPK3 GNG11 GNG11 GRIN1 GRIN1 GUCY1B1 GUCY1B1 FOS FOS PER2 PER2 MTNR1B MTNR1B PRKG2 PRKG2 GRIN2B GRIN2B CACNA1C CACNA1C ENSMNEP00000013158 ENSMNEP00000013158 CREB1 CREB1 MAPK1 MAPK1 MTNR1A MTNR1A GNGT2 GNGT2 GNG2 GNG2 GNG10 GNG10 GNG8 GNG8 GNAQ GNAQ KCNJ5 KCNJ5 GRIN2C GRIN2C GNB2 GNB2 PLCB4 PLCB4 ADCY1 ADCY1 GNB4 GNB4 ADCY7 ADCY7 PLCB2 PLCB2 GNG7 GNG7 PLCB3 PLCB3 RASD1 RASD1 PRKCB PRKCB ENSMNEP00000005141 ENSMNEP00000005141 GRIA2 GRIA2 ADCY9 ADCY9 ENSMNEP00000002738 ENSMNEP00000002738 RYR2 RYR2 CALML3 CALML3 PER3 PER3 LOC105470579 LOC105470579
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALM1Calmodulin 1. (149 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
GNAO1G protein subunit alpha o1. (354 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (388 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1299 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1214 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (577 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (556 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNB5G protein subunit beta 5. (409 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2209 aa)
ENSMNEP00000034688Uncharacterized protein. (288 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (893 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
ARSIArylsulfatase family member I. (569 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GNAI1G protein subunit alpha i1. (422 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
CALM3Calmodulin 3. (149 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PER1Period circadian regulator 1. (1366 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CALM2Calmodulin 1; Belongs to the calmodulin family. (149 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
GNB3G protein subunit beta 3. (340 aa)
FBXO21F-box protein 21. (628 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
ENSMNEP00000025595Uncharacterized protein. (348 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2343 aa)
GNB1G protein subunit beta 1. (340 aa)
NOS1APPID domain-containing protein. (695 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
ADCY10Adenylate cyclase 10. (1597 aa)
GNAI3G protein subunit alpha i3. (328 aa)
CALML6Calmodulin like 6. (181 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
RYR1Ryanodine receptor 1. (4913 aa)
GNASGNAS complex locus. (1007 aa)
GNAI2G protein subunit alpha i2. (355 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
LOC105490737Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (583 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2217 aa)
CALML4Calmodulin like 4. (193 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
ENSMNEP00000016414Uncharacterized protein; Belongs to the calmodulin family. (179 aa)
RYR3Ryanodine receptor 3. (4856 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (996 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PER2Period circadian regulator 2. (1280 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (362 aa)
PRKG2cGMP-dependent protein kinase. (814 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
ENSMNEP00000013158Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (352 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNAQG protein subunit alpha q. (359 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (432 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1242 aa)
GNB2G protein subunit beta 2. (340 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1088 aa)
GNB4G protein subunit beta 4. (340 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1174 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
RASD1Ras related dexamethasone induced 1. (279 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ENSMNEP00000005141Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ENSMNEP00000002738Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
RYR2Ryanodine receptor 2. (4951 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
PER3Period circadian regulator 3. (1180 aa)
LOC105470579Uncharacterized protein. (245 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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