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BAD | BCL2 associated agonist of cell death. (167 aa) | ||||
ENSMNEP00000000010 | Uncharacterized protein. (141 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) | ||||
ERAS | ES cell expressed Ras. (233 aa) | ||||
BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (312 aa) | ||||
CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) | ||||
NTF4 | Neurotrophin 4; Belongs to the NGF-beta family. (210 aa) | ||||
SH2B2 | SH2B adaptor protein 2. (680 aa) | ||||
ZNF274 | Zinc finger protein 274. (653 aa) | ||||
RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) | ||||
ENSMNEP00000004647 | Uncharacterized protein. (185 aa) | ||||
IRAK2 | Interleukin 1 receptor associated kinase 2. (625 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (717 aa) | ||||
ENSMNEP00000005419 | Uncharacterized protein. (114 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (763 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1. (361 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) | ||||
BEX3 | Brain expressed X-linked 3. (123 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1148 aa) | ||||
RPS6KA2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (723 aa) | ||||
PIK3R2 | Uncharacterized protein. (668 aa) | ||||
RPS6KA6 | Ribosomal protein S6 kinase. (745 aa) | ||||
ZFR | Zinc finger RNA binding protein. (1074 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (968 aa) | ||||
RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1265 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (838 aa) | ||||
ENSMNEP00000011545 | Uncharacterized protein. (81 aa) | ||||
ENSMNEP00000011554 | Uncharacterized protein. (157 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (366 aa) | ||||
ENSMNEP00000012002 | TNF receptor-associated factor. (457 aa) | ||||
ENSMNEP00000012679 | Uncharacterized protein. (262 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
CAMK4 | Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa) | ||||
RAP1A | RAP1A, member of RAS oncogene family. (184 aa) | ||||
SH2B3 | SH2B adaptor protein 3. (570 aa) | ||||
MAGED1 | MAGE family member D1. (834 aa) | ||||
ARHGDIB | Rho GDP dissociation inhibitor beta. (201 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
ENSMNEP00000016333 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (190 aa) | ||||
ENSMNEP00000016378 | Protein kinase domain-containing protein. (652 aa) | ||||
ENSMNEP00000016414 | Uncharacterized protein; Belongs to the calmodulin family. (179 aa) | ||||
PRDM4 | PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (801 aa) | ||||
GAB1 | GRB2 associated binding protein 1. (724 aa) | ||||
IRAK3 | Interleukin 1 receptor associated kinase 3. (596 aa) | ||||
CALML4 | Calmodulin like 4. (193 aa) | ||||
CEP152 | Centrosomal protein 152. (1703 aa) | ||||
ZSCAN1 | Zinc finger and SCAN domain containing 1. (398 aa) | ||||
CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) | ||||
ENSMNEP00000019824 | Uncharacterized protein. (194 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
SORT1 | Sortilin. (831 aa) | ||||
CDC42 | Uncharacterized protein. (191 aa) | ||||
NTRK3 | Tyrosine-protein kinase receptor. (866 aa) | ||||
GCNA | Germ cell nuclear acidic peptidase. (672 aa) | ||||
CSK | Tyrosine-protein kinase. (450 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (203 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (239 aa) | ||||
SHC4 | SHC adaptor protein 4. (630 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (384 aa) | ||||
FRS2 | Fibroblast growth factor receptor substrate 2. (515 aa) | ||||
PVALEF | Parvalbumin like EF-hand containing. (133 aa) | ||||
CALML6 | Calmodulin like 6. (181 aa) | ||||
TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa) | ||||
PSEN2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa) | ||||
ENSMNEP00000025369 | Uncharacterized protein. (129 aa) | ||||
SHC3 | SHC adaptor protein 3. (598 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
RHOC | Ras homolog family member C. (193 aa) | ||||
CALM2 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
NGF | Nerve growth factor; Belongs to the NGF-beta family. (123 aa) | ||||
ENSMNEP00000027695 | Uncharacterized protein. (445 aa) | ||||
PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) | ||||
ENSMNEP00000027902 | Protein kinase domain-containing protein. (365 aa) | ||||
ATF4 | Activating transcription factor 4. (351 aa) | ||||
MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (657 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) | ||||
ARHGDIA | Rho GDP dissociation inhibitor alpha. (235 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
ENSMNEP00000029022 | Uncharacterized protein. (185 aa) | ||||
RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) | ||||
CALM3 | Calmodulin 3. (149 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (270 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
RAC1 | Rac family small GTPase 1. (211 aa) | ||||
PRKCD | Protein kinase C. (729 aa) | ||||
MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1345 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (666 aa) | ||||
ARSI | Arylsulfatase family member I. (569 aa) | ||||
CRK | CRK proto-oncogene, adaptor protein. (304 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (317 aa) | ||||
IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) | ||||
FOXO3 | Forkhead box O3. (716 aa) | ||||
NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (278 aa) | ||||
SHC1 | SHC adaptor protein 1. (584 aa) | ||||
FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) | ||||
SHC2 | Uncharacterized protein. (572 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (365 aa) | ||||
RAP1B | Uncharacterized protein. (137 aa) | ||||
MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (813 aa) | ||||
CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (556 aa) | ||||
MAPK9 | Mitogen-activated protein kinase 9. (354 aa) | ||||
RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1241 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (463 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
ENSMNEP00000039571 | Uncharacterized protein. (136 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) | ||||
MATK | Tyrosine-protein kinase. (539 aa) | ||||
SH2B1 | SH2B adaptor protein 1. (756 aa) | ||||
YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1374 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (489 aa) | ||||
RPS6KA1 | Ribosomal protein S6 kinase. (744 aa) | ||||
NGFR | Nerve growth factor receptor. (439 aa) | ||||
ZFR2 | Zinc finger RNA binding protein 2. (908 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (796 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (472 aa) | ||||
CALM1 | Calmodulin 1. (149 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa) | ||||
MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (383 aa) | ||||
CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) | ||||
KIDINS220 | Kinase D interacting substrate 220. (1771 aa) | ||||
NFKBIB | NFKB inhibitor beta. (356 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
ENSMNEP00000045127 | Uncharacterized protein. (183 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (189 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
CSDE1 | Cold shock domain containing E1. (844 aa) | ||||
PDPK1 | 3-phosphoinositide dependent protein kinase 1. (582 aa) | ||||
ARHGDIG | Rho GDP dissociation inhibitor gamma. (225 aa) | ||||
PPP1R14B | Uncharacterized protein. (208 aa) | ||||
CAMK2D | Calcium/calmodulin dependent protein kinase II delta. (533 aa) |