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ATP1B3 ATP1B3 GCG GCG ENSMNEP00000037017 ENSMNEP00000037017 CREB3L1 CREB3L1 CAMK2G CAMK2G FXYD2 FXYD2 CACNA1D CACNA1D CREB3L2 CREB3L2 ENSMNEP00000034688 ENSMNEP00000034688 CCK CCK ADCY8 ADCY8 KCNMB4 KCNMB4 SNAP25 SNAP25 CREB3L3 CREB3L3 ARSI ARSI CAMK2B CAMK2B PRKACB PRKACB CCKAR CCKAR ATF2 ATF2 KCNMB1 KCNMB1 PRKCG PRKCG PRKCA PRKCA ATF4 ATF4 KCNMB2 KCNMB2 KCNN4 KCNN4 GCK GCK ITPR3 ITPR3 INS INS ATP1A2 ATP1A2 ATP1B4 ATP1B4 ADCY4 ADCY4 SLC2A1 SLC2A1 PTRHD1 PTRHD1 ATP1A1 ATP1A1 GNAS GNAS CREB5 CREB5 ADCYAP1 ADCYAP1 STX1A STX1A PCLO PCLO ATP1A4 ATP1A4 ATP1A3 ATP1A3 PDX1 PDX1 KCNU1 KCNU1 FAP FAP CACNA1C CACNA1C RAPGEF4 RAPGEF4 KCNN1 KCNN1 RAB3A RAB3A CREB1 CREB1 KCNMB3 KCNMB3 RAB3C RAB3C GLP1R GLP1R GNAQ GNAQ PLCB4 PLCB4 ATF6B ATF6B ADCY1 ADCY1 ADCY7 ADCY7 PLCB2 PLCB2 PLCB3 PLCB3 PRKCB PRKCB CACNA1S CACNA1S KCNJ11 KCNJ11 RAB3B RAB3B FFAR1 FFAR1 GPR119 GPR119 ABCC8 ABCC8 ADCY9 ADCY9 CACNA1F CACNA1F RYR2 RYR2 VAMP2 VAMP2 LOC105470579 LOC105470579 KCNN2 KCNN2 PLCB1 PLCB1 ATP1B2 ATP1B2 ADCY2 ADCY2 ADCY3 ADCY3 GNA11 GNA11 CAMK2D CAMK2D TRPM4 TRPM4 CAMK2A CAMK2A CREB3 CREB3 ADCY5 ADCY5 ADCY6 ADCY6 PRKACA PRKACA ADCYAP1R1 ADCYAP1R1 TNIK TNIK KCNN3 KCNN3 CREB3L4 CREB3L4 ATP1B1 ATP1B1 GIP GIP KCNMA1 KCNMA1 SLC2A2 SLC2A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
GCGGlucagon. (180 aa)
ENSMNEP00000037017Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (249 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (556 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2209 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
ENSMNEP00000034688Uncharacterized protein. (288 aa)
CCKCholecystokinin. (115 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (446 aa)
ARSIArylsulfatase family member I. (569 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ATF4Activating transcription factor 4. (351 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (268 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
GCKPhosphotransferase. (466 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
GNASGNAS complex locus. (1007 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
PCLOPiccolo presynaptic cytomatrix protein. (5191 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
ATP1A3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1229 aa)
PDX1Pancreatic and duodenal homeobox 1. (281 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1149 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (543 aa)
RAB3ARAB3A, member RAS oncogene family. (177 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (280 aa)
RAB3CRAB3C, member RAS oncogene family. (227 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
GNAQG protein subunit alpha q. (359 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ATF6BActivating transcription factor 6 beta. (710 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1088 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1174 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1867 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
RAB3BRAB3B, member RAS oncogene family. (219 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
GPR119G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1960 aa)
RYR2Ryanodine receptor 2. (4951 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
LOC105470579Uncharacterized protein. (245 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (844 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
GNA11G protein subunit alpha 11. (346 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (992 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1214 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (577 aa)
TNIKTRAF2 and NCK interacting kinase. (1359 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (744 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (422 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
GIPGastric inhibitory polypeptide. (153 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1275 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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