STRINGSTRING
AKT1 AKT1 PIK3CB PIK3CB ERAS ERAS STAT1 STAT1 SOCS3 SOCS3 SOCS5 SOCS5 SOCS1 SOCS1 SOCS4 SOCS4 CCDC170 CCDC170 TNFRSF11A TNFRSF11A SOCS6 SOCS6 GSK3B GSK3B SRC SRC MAP2K1 MAP2K1 SOS2 SOS2 CISH CISH PIK3R2 PIK3R2 SOCS2 SOCS2 CSN2 CSN2 LOC105497223 LOC105497223 NFKB1 NFKB1 PRLR PRLR MAPK1 MAPK1 MAPK11 MAPK11 MAPK8 MAPK8 JAK2 JAK2 CCND2 CCND2 FOS FOS TNFSF11 TNFSF11 MAPK3 MAPK3 IRF1 IRF1 SOCS7 SOCS7 STAT5A STAT5A STAT5B STAT5B ESR2 ESR2 ESR1 ESR1 STAT3 STAT3 CEP152 CEP152 PIK3CA PIK3CA SHC4 SHC4 LHCGR LHCGR ENSMNEP00000024501 ENSMNEP00000024501 SHC3 SHC3 INS INS CSDE1 CSDE1 MAPK14 MAPK14 KRAS KRAS CGA CGA PRL PRL NRAS NRAS TNIK TNIK MAP2K2 MAP2K2 SOS1 SOS1 MAPK10 MAPK10 MAPK12 MAPK12 AKT3 AKT3 PIK3R3 PIK3R3 RELCH RELCH SLC2A2 SLC2A2 MAPK9 MAPK9 CYP17A1 CYP17A1 CCND1 CCND1 MAPK13 MAPK13 RAF1 RAF1 SHC2 SHC2 SHC1 SHC1 FOXO3 FOXO3 HRAS HRAS PIK3CD PIK3CD PIK3R1 PIK3R1 ENSMNEP00000030203 ENSMNEP00000030203 AKT2 AKT2 RELA RELA ENSMNEP00000027902 ENSMNEP00000027902 TH TH GRB2 GRB2 GCK GCK ELF5 ELF5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
ERASES cell expressed Ras. (233 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
SOCS1Suppressor of cytokine signaling 1. (213 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
CCDC170Coiled-coil domain containing 170. (763 aa)
TNFRSF11ATNF receptor superfamily member 11a. (616 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
SRCTyrosine-protein kinase. (644 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (361 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
CISHCytokine inducible SH2 containing protein. (274 aa)
PIK3R2Uncharacterized protein. (668 aa)
SOCS2Suppressor of cytokine signaling 2. (210 aa)
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (226 aa)
LOC105497223Cys_knot domain-containing protein. (165 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
IRF1Interferon regulatory factor. (325 aa)
SOCS7Suppressor of cytokine signaling 7. (580 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
STAT5BSignal transducer and activator of transcription. (783 aa)
ESR2Estrogen receptor 2. (530 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
STAT3Signal transducer and activator of transcription. (660 aa)
CEP152Centrosomal protein 152. (1703 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SHC4SHC adaptor protein 4. (630 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (703 aa)
ENSMNEP00000024501Uncharacterized protein. (456 aa)
SHC3SHC adaptor protein 3. (598 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
CSDE1Cold shock domain containing E1. (844 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (150 aa)
PRLProlactin. (227 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
TNIKTRAF2 and NCK interacting kinase. (1359 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa)
MAPK10Mitogen-activated protein kinase. (489 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (463 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
MAPK9Mitogen-activated protein kinase 9. (354 aa)
CYP17A1Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (508 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
SHC2Uncharacterized protein. (572 aa)
SHC1SHC adaptor protein 1. (584 aa)
FOXO3Forkhead box O3. (716 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSMNEP00000030203Cys_knot domain-containing protein. (141 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
ENSMNEP00000027902Protein kinase domain-containing protein. (365 aa)
THTyrosine hydroxylase. (529 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
GCKPhosphotransferase. (466 aa)
ELF5E74 like ETS transcription factor 5. (265 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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