STRINGSTRING
GPX8 GPX8 PRKACA PRKACA ADCY6 ADCY6 ADCY5 ADCY5 GPX1 GPX1 CREB3 CREB3 TPO TPO DUOXA2 DUOXA2 ALB ALB PLCB1 PLCB1 ATP1B2 ATP1B2 ADCY2 ADCY2 CGA CGA ADCY3 ADCY3 CREB3L4 CREB3L4 SLC5A5 SLC5A5 ENSMNEP00000041082 ENSMNEP00000041082 ATP1B1 ATP1B1 TTF2 TTF2 ADCY4 ADCY4 TSHB TSHB ENSMNEP00000037017 ENSMNEP00000037017 CREB3L1 CREB3L1 FXYD2 FXYD2 CREB3L2 CREB3L2 ENSMNEP00000034688 ENSMNEP00000034688 ADCY8 ADCY8 CREB3L3 CREB3L3 PRKACB PRKACB PDIA4 PDIA4 CANX CANX ATF2 ATF2 PRKCG PRKCG PRKCA PRKCA DUOX1 DUOX1 ATF4 ATF4 PAX8 PAX8 GPX5 GPX5 ITPR3 ITPR3 CLEC10A CLEC10A SYCP1 SYCP1 DUOX2 DUOX2 ATP1A2 ATP1A2 ASGR1 ASGR1 IYD IYD ATP1B4 ATP1B4 ITPR1 ITPR1 ATP1B3 ATP1B3 TTR TTR PTRHD1 PTRHD1 ATP1A1 ATP1A1 GNAS GNAS GSR GSR CREB5 CREB5 HSP90B1 HSP90B1 GPX6 GPX6 TSHR TSHR ENSMNEP00000017745 ENSMNEP00000017745 ATP1A4 ATP1A4 SERPINA9 SERPINA9 ATP1A3 ATP1A3 SLC26A4 SLC26A4 ASGR2 ASGR2 GPX7 GPX7 GPX3 GPX3 CREB1 CREB1 TG TG GNAQ GNAQ SERPINA7 SERPINA7 PLCB4 PLCB4 ATF6B ATF6B ADCY1 ADCY1 ADCY7 ADCY7 PLCB2 PLCB2 PLCB3 PLCB3 TTF1 TTF1 PRKCB PRKCB GPX2 GPX2 HSPA5 HSPA5 ITPR2 ITPR2 ADCY9 ADCY9 LRP2 LRP2 ENSMNEP00000002118 ENSMNEP00000002118 LOC105470579 LOC105470579
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1214 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (197 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
TPOThyroid peroxidase. (926 aa)
DUOXA2Dual oxidase maturation factor 2. (320 aa)
ALBAlbumin. (608 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (150 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (422 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (591 aa)
ENSMNEP00000041082Uncharacterized protein; Belongs to the heat shock protein 70 family. (558 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
TTF2Transcription termination factor 2. (1145 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
TSHBThyroid stimulating hormone subunit beta. (158 aa)
ENSMNEP00000037017Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (249 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
ENSMNEP00000034688Uncharacterized protein. (288 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (446 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
PDIA4Protein disulfide-isomerase. (574 aa)
CANXCalnexin. (566 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
DUOX1Dual oxidase 1. (1551 aa)
ATF4Activating transcription factor 4. (351 aa)
PAX8Paired box 8. (544 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
CLEC10AC-type lectin domain containing 10A. (315 aa)
SYCP1Synaptonemal complex protein 1. (976 aa)
DUOX2Dual oxidase 2. (1546 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
ASGR1Asialoglycoprotein receptor 1. (294 aa)
IYDIodotyrosine deiodinase. (289 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (157 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
GNASGNAS complex locus. (1007 aa)
GSRGlutathione-disulfide reductase. (472 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
HSP90B1Heat shock protein 90 beta family member 1. (804 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (220 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
ENSMNEP00000017745Uncharacterized protein. (58 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
SERPINA9Serpin family A member 9; Belongs to the serpin family. (435 aa)
ATP1A3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1229 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
ASGR2Asialoglycoprotein receptor 2. (306 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (175 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (225 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
TGThyroglobulin. (2769 aa)
GNAQG protein subunit alpha q. (359 aa)
SERPINA7Serpin family A member 7; Belongs to the serpin family. (415 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ATF6BActivating transcription factor 6 beta. (710 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1088 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1174 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
TTF1Transcription termination factor 1. (837 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (150 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
LRP2LDL receptor related protein 2. (4655 aa)
ENSMNEP00000002118Uncharacterized protein. (381 aa)
LOC105470579Uncharacterized protein. (245 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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