STRINGSTRING
NDUFS2 NDUFS2 ENSMNEP00000045127 ENSMNEP00000045127 DDIT3 DDIT3 NDUFB5 NDUFB5 LOC105480794 LOC105480794 ENSMNEP00000000400 ENSMNEP00000000400 LOC105475022 LOC105475022 ERN1 ERN1 PIK3CB PIK3CB IL6 IL6 LOC105487134 LOC105487134 LOC105487609 LOC105487609 ENSMNEP00000000885 ENSMNEP00000000885 NDUFA11 NDUFA11 LOC105493947 LOC105493947 NDUFB10 NDUFB10 LOC105491771 LOC105491771 LOC105497820 LOC105497820 PRKAB2 PRKAB2 SOCS3 SOCS3 ENSMNEP00000001765 ENSMNEP00000001765 PKLR PKLR ENSMNEP00000002068 ENSMNEP00000002068 LOC105495842 LOC105495842 LOC105484999 LOC105484999 UQCR10 UQCR10 LOC105486922 LOC105486922 ENSMNEP00000004019 ENSMNEP00000004019 ENSMNEP00000004038 ENSMNEP00000004038 LOC105477037 LOC105477037 TRAF2 TRAF2 LOC105495023 LOC105495023 ENSMNEP00000004647 ENSMNEP00000004647 ENSMNEP00000004680 ENSMNEP00000004680 LOC105471304 LOC105471304 NDUFB8 NDUFB8 NDUFA10 NDUFA10 PRKAA2 PRKAA2 INSR INSR LOC105464914 LOC105464914 COX7B2 COX7B2 LOC105477715 LOC105477715 LOC105492342 LOC105492342 NDUFV2 NDUFV2 LOC105483680 LOC105483680 GSK3B GSK3B ENSMNEP00000006173 ENSMNEP00000006173 NDUFC2 NDUFC2 NDUFS5 NDUFS5 FAS FAS ENSMNEP00000007551 ENSMNEP00000007551 LOC105479441 LOC105479441 PIK3R2 PIK3R2 NDUFA12 NDUFA12 ENSMNEP00000008653 ENSMNEP00000008653 ADIPOR1 ADIPOR1 COX7A1 COX7A1 NDUFS8 NDUFS8 LOC105467520 LOC105467520 ENSMNEP00000009746 ENSMNEP00000009746 RXRA RXRA MLX MLX ENSMNEP00000010457 ENSMNEP00000010457 ENSMNEP00000010588 ENSMNEP00000010588 ITCH ITCH NFKB1 NFKB1 NDUFB3 NDUFB3 PRKAA1 PRKAA1 ENSMNEP00000011554 ENSMNEP00000011554 TNFRSF1A TNFRSF1A NDUFA3 NDUFA3 NDUFS3 NDUFS3 COX6C COX6C NDUFA4L2 NDUFA4L2 NDUFS6 NDUFS6 MAPK8 MAPK8 LOC105487652 LOC105487652 MLXIPL MLXIPL NDUFA4 NDUFA4 COX4I1 COX4I1 ENSMNEP00000013877 ENSMNEP00000013877 NDUFS4 NDUFS4 FOS FOS NDUFV3 NDUFV3 ENSMNEP00000015708 ENSMNEP00000015708 ENSMNEP00000015858 ENSMNEP00000015858 BID BID NR1H3 NR1H3 ENSMNEP00000016480 ENSMNEP00000016480 ENSMNEP00000016679 ENSMNEP00000016679 PRKAG1 PRKAG1 IRS2 IRS2 ENSMNEP00000017709 ENSMNEP00000017709 ADIPOR2 ADIPOR2 NDUFS1 NDUFS1 EIF2AK3 EIF2AK3 EIF2S1 EIF2S1 LEPR LEPR ENSMNEP00000018478 ENSMNEP00000018478 NDUFB2 NDUFB2 LOC105464285 LOC105464285 SREBF1 SREBF1 NDUFA2 NDUFA2 NDUFA6 NDUFA6 PIK3CA PIK3CA IL6R IL6R LOC105472894 LOC105472894 XBP1 XBP1 NDUFB4 NDUFB4 CDC42 CDC42 PPARA PPARA ENSMNEP00000021592 ENSMNEP00000021592 FAM71E2 FAM71E2 CXCL8 CXCL8 LEP LEP ENSMNEP00000022325 ENSMNEP00000022325 BAX BAX ENSMNEP00000023483 ENSMNEP00000023483 SDHB SDHB NDUFA8 NDUFA8 NDUFA7 NDUFA7 COX6B2 COX6B2 NDUFB7 NDUFB7 ENSMNEP00000025122 ENSMNEP00000025122 ENSMNEP00000025713 ENSMNEP00000025713 PRKAB1 PRKAB1 CASP7 CASP7 CYP2E1 CYP2E1 INS INS AKT1 AKT1 COX6A1 COX6A1 SDHD SDHD YJEFN3 YJEFN3 ENSMNEP00000028010 ENSMNEP00000028010 PRKAG3 PRKAG3 ATF4 ATF4 RELA RELA NDUFA1 NDUFA1 AKT2 AKT2 ENSMNEP00000029022 ENSMNEP00000029022 TNF TNF CYC1 CYC1 LOC112423181 LOC112423181 PRKAG2 PRKAG2 ENSMNEP00000029995 ENSMNEP00000029995 KIAA1958 KIAA1958 NDUFA9 NDUFA9 GSK3A GSK3A ENSMNEP00000030369 ENSMNEP00000030369 PIK3R1 PIK3R1 NDUFAB1 NDUFAB1 PIK3CD PIK3CD NDUFS7 NDUFS7 NDUFB9 NDUFB9 RAC1 RAC1 NDUFB1 NDUFB1 ENSMNEP00000032372 ENSMNEP00000032372 NDUFA13 NDUFA13 CASP8 CASP8 NDUFA5 NDUFA5 ENSMNEP00000032960 ENSMNEP00000032960 IL1B IL1B IKBKB IKBKB LOC105490971 LOC105490971 IL1A IL1A ENSMNEP00000034084 ENSMNEP00000034084 MAP3K11 MAP3K11 NDUFB11 NDUFB11 FASLG FASLG ENSMNEP00000034573 ENSMNEP00000034573 UQCRB UQCRB CYCS CYCS ENSMNEP00000035443 ENSMNEP00000035443 C7orf31 C7orf31 MLXIP MLXIP NDUFV1 NDUFV1 MAPK9 MAPK9 UQCRQ UQCRQ COX8A COX8A COX4I2 COX4I2 NDUFC1 NDUFC1 IRS1 IRS1 ENSMNEP00000038415 ENSMNEP00000038415 PIK3R3 PIK3R3 AKT3 AKT3 TGFB1 TGFB1 ENSMNEP00000040099 ENSMNEP00000040099 ADIPOQ ADIPOQ ENSMNEP00000040454 ENSMNEP00000040454 MAP3K5 MAP3K5 SDHC SDHC MAPK10 MAPK10 COX6A2 COX6A2 NDUFB6 NDUFB6 UQCRC1 UQCRC1 ENSMNEP00000041628 ENSMNEP00000041628 ENSMNEP00000041867 ENSMNEP00000041867 ENSMNEP00000041936 ENSMNEP00000041936 ENSMNEP00000042051 ENSMNEP00000042051 BCL2L11 BCL2L11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NDUFS2Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (463 aa)
ENSMNEP00000045127Uncharacterized protein. (183 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
NDUFB5NADH:ubiquinone oxidoreductase subunit B5. (189 aa)
LOC105480794Uncharacterized protein. (157 aa)
ENSMNEP00000000400Uncharacterized protein. (69 aa)
LOC105475022Uncharacterized protein. (64 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (978 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
IL6Interleukin 6. (214 aa)
LOC105487134Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa)
LOC105487609Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMNEP00000000885Uncharacterized protein. (109 aa)
NDUFA11NADH:ubiquinone oxidoreductase subunit A11. (185 aa)
LOC105493947Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (178 aa)
LOC105491771Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105497820Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
ENSMNEP00000001765Uncharacterized protein. (98 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (566 aa)
ENSMNEP00000002068Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (157 aa)
LOC105495842Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105484999Uncharacterized protein; Belongs to the peptidase M16 family. (453 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (63 aa)
LOC105486922Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMNEP00000004019Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
ENSMNEP00000004038Uncharacterized protein. (72 aa)
LOC105477037Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (532 aa)
LOC105495023Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa)
ENSMNEP00000004647Uncharacterized protein. (185 aa)
ENSMNEP00000004680Uncharacterized protein. (83 aa)
LOC105471304Uncharacterized protein. (80 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (429 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
INSRTyrosine-protein kinase receptor. (1306 aa)
LOC105464914Uncharacterized protein. (114 aa)
COX7B2Cytochrome c oxidase subunit 7B2. (81 aa)
LOC105477715Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC105492342Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (249 aa)
LOC105483680Uncharacterized protein. (153 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
ENSMNEP00000006173Uncharacterized protein. (98 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (119 aa)
NDUFS5NADH:ubiquinone oxidoreductase subunit S5. (106 aa)
FASTumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa)
ENSMNEP00000007551Uncharacterized protein. (571 aa)
LOC105479441Uncharacterized protein. (115 aa)
PIK3R2Uncharacterized protein. (668 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
ENSMNEP00000008653Uncharacterized protein. (327 aa)
ADIPOR1Adiponectin receptor 1. (274 aa)
COX7A1Cytochrome c oxidase subunit 7A1. (79 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (210 aa)
LOC105467520Uncharacterized protein. (72 aa)
ENSMNEP00000009746Uncharacterized protein. (434 aa)
RXRARetinoid X receptor alpha. (523 aa)
MLXMAX dimerization protein MLX. (298 aa)
ENSMNEP00000010457Uncharacterized protein. (70 aa)
ENSMNEP00000010588Uncharacterized protein. (107 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
NDUFB3Uncharacterized protein. (98 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
ENSMNEP00000011554Uncharacterized protein. (157 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
NDUFA3NADH:ubiquinone oxidoreductase subunit A3. (84 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (265 aa)
COX6CCytochrome c oxidase subunit 6C. (75 aa)
NDUFA4L2NDUFA4 mitochondrial complex associated like 2. (94 aa)
NDUFS6NADH:ubiquinone oxidoreductase subunit S6. (172 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC105487652Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
MLXIPLMLX interacting protein like. (827 aa)
NDUFA4Uncharacterized protein. (81 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
ENSMNEP00000013877UCR_hinge domain-containing protein. (121 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (174 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
NDUFV3NADH:ubiquinone oxidoreductase subunit V3. (473 aa)
ENSMNEP00000015708Uncharacterized protein. (129 aa)
ENSMNEP00000015858Uncharacterized protein. (110 aa)
BIDBH3 interacting domain death agonist. (266 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (466 aa)
ENSMNEP00000016480Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (110 aa)
ENSMNEP00000016679Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (101 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
IRS2Insulin receptor substrate 2. (1334 aa)
ENSMNEP00000017709Uncharacterized protein. (67 aa)
ADIPOR2Adiponectin receptor 2. (386 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1. (728 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
LEPRLeptin receptor. (1163 aa)
ENSMNEP00000018478Uncharacterized protein. (158 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (105 aa)
LOC105464285Cytochrome c oxidase subunit 7B, mitochondrial. (80 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa)
NDUFA6Uncharacterized protein; Belongs to the complex I LYR family. (154 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
IL6RInterleukin 6 receptor. (467 aa)
LOC105472894Uncharacterized protein. (129 aa)
XBP1BZIP domain-containing protein. (380 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (128 aa)
CDC42Uncharacterized protein. (191 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
ENSMNEP00000021592Uncharacterized protein. (148 aa)
FAM71E2DUF3699 domain-containing protein. (858 aa)
CXCL8Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ENSMNEP00000022325Uncharacterized protein. (238 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
ENSMNEP00000023483Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (374 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (262 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
NDUFA7Uncharacterized protein. (113 aa)
COX6B2Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (88 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (137 aa)
ENSMNEP00000025122Uncharacterized protein. (144 aa)
ENSMNEP00000025713Uncharacterized protein. (141 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (377 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (494 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
YJEFN3YjeF N-terminal domain containing 3. (301 aa)
ENSMNEP00000028010Uncharacterized protein. (137 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
ATF4Activating transcription factor 4. (351 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (70 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSMNEP00000029022Uncharacterized protein. (185 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CYC1Cytochrome c1. (325 aa)
LOC112423181Uncharacterized protein. (63 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa)
ENSMNEP00000029995Uncharacterized protein. (90 aa)
KIAA1958KIAA1958. (744 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (377 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
ENSMNEP00000030369Uncharacterized protein. (612 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (213 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (223 aa)
RAC1Rac family small GTPase 1. (211 aa)
NDUFB1Uncharacterized protein. (102 aa)
ENSMNEP00000032372Uncharacterized protein. (79 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (163 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (487 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (116 aa)
ENSMNEP00000032960Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (90 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
LOC105490971Uncharacterized protein. (153 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (224 aa)
ENSMNEP00000034084Uncharacterized protein; Belongs to the cytochrome c oxidase subunit 6A family. (104 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (847 aa)
NDUFB11Uncharacterized protein. (153 aa)
FASLGTumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa)
ENSMNEP00000034573Uncharacterized protein. (166 aa)
UQCRBUbiquinol-cytochrome c reductase binding protein. (161 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMNEP00000035443Uncharacterized protein. (153 aa)
C7orf31Chromosome 7 open reading frame 31. (590 aa)
MLXIPMLX interacting protein. (919 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
MAPK9Mitogen-activated protein kinase 9. (354 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (171 aa)
NDUFC1NADH:ubiquinone oxidoreductase subunit C1. (76 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
ENSMNEP00000038415Uncharacterized protein. (109 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (463 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
ENSMNEP00000040099Uncharacterized protein. (118 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (274 aa)
ENSMNEP00000040454Uncharacterized protein. (102 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1374 aa)
SDHCUncharacterized protein. (169 aa)
MAPK10Mitogen-activated protein kinase. (489 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (128 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
ENSMNEP00000041628Uncharacterized protein. (53 aa)
ENSMNEP00000041867Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa)
ENSMNEP00000041936Uncharacterized protein. (98 aa)
ENSMNEP00000042051Uncharacterized protein. (81 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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