(121 nodes) Protein digestion and absorption network (Macaca nemestrina)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	COL21A1	Collagen type XXI alpha 1 chain. (1008 aa)
	ENSMNEP00000026414	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (236 aa)
	COL6A3	Collagen type VI alpha 3 chain. (2582 aa)
	DPP4	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
	COL23A1	Collagen type XXIII alpha 1 chain. (393 aa)
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
	COL6A2	Collagen type VI alpha 2 chain. (1019 aa)
	COL28A1	Collagen type XXVIII alpha 1 chain. (1155 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
	SLC3A1	Solute carrier family 3 member 1. (685 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
	CELA2B	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (237 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
	ENSMNEP00000021568	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (244 aa)
	COL14A1	Collagen type XIV alpha 1 chain. (1796 aa)
	COL2A1	Collagen type II alpha 1 chain. (1487 aa)
	CELA2A	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (264 aa)
	SLC15A1	Solute carrier family 15 member 1. (708 aa)
	CPA3	Carboxypeptidase A3. (417 aa)
	COL4A5	Collagen type IV alpha 5 chain. (1691 aa)
	CPA4	Carboxypeptidase A4. (421 aa)
	COL4A4	Collagen type IV alpha 4 chain. (1692 aa)
	ATP1A4	Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
	COL5A2	Collagen type V alpha 2 chain. (1499 aa)
	COL15A1	Uncharacterized protein. (1388 aa)
	ENSMNEP00000016710	Uncharacterized protein. (1417 aa)
	ATP1A3	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1229 aa)
	SLC8A2	Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
	CTRB2	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
	COL1A2	Collagen type I alpha 2 chain. (1366 aa)
	SLC36A2	Solute carrier family 36 member 2. (451 aa)
	COL25A1	Collagen type XXV alpha 1 chain. (654 aa)
	COL18A1	Collagen type XVIII alpha 1 chain. (1754 aa)
	LOC105490397	Uncharacterized protein. (2348 aa)
	COL5A3	Collagen type V alpha 3 chain. (1746 aa)
	COL3A1	Collagen type III alpha 1 chain. (1466 aa)
	COL16A1	Collagen type XVI alpha 1 chain. (1604 aa)
	COL9A1	Collagen type IX alpha 1 chain. (921 aa)
	LOC105497458	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (219 aa)
	C1QTNF2	C1q and TNF related 2. (330 aa)
	SLC16A10	Solute carrier family 16 member 10. (515 aa)
	VWA2	Uncharacterized protein. (421 aa)
	COL17A1	Collagen type XVII alpha 1 chain. (1406 aa)
	SLC7A6	Solute carrier family 7 member 6. (515 aa)
	SLC1A1	Solute carrier family 1 member 1. (524 aa)
	ELN	Elastin. (734 aa)
	PRCP	Prolylcarboxypeptidase. (516 aa)
	SLC38A2	Solute carrier family 38 member 2. (506 aa)
	COL8A1	Collagen type VIII alpha 1 chain. (746 aa)
	LOC105471241	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (273 aa)
	COL4A3	Collagen type IV alpha 3 chain. (1670 aa)
	SLC36A1	Solute carrier family 36 member 1. (476 aa)
	CTRC	Chymotrypsin C; Belongs to the peptidase S1 family. (267 aa)
	SLC36A3	Solute carrier family 36 member 3. (510 aa)
	COL6A6	Collagen type VI alpha 6 chain. (2265 aa)
	KCNE3	Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa)
	COL11A1	Collagen type XI alpha 1 chain. (1818 aa)
	COL11A2	Collagen type XI alpha 2 chain. (1736 aa)
	COL10A1	Collagen type X alpha 1 chain. (680 aa)
	COL4A2	Collagen type IV alpha 2 chain. (1683 aa)
	XPNPEP2	X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family. (674 aa)
	ENSMNEP00000001780	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (354 aa)
	COL26A1	Collagen type XXVI alpha 1 chain. (441 aa)
	SLC9A3	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (523 aa)
	SLC6A19	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (691 aa)
	KCNK5	Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (499 aa)
	PRSS37	Serine protease 37. (235 aa)
	LOC112424852	Serine protease 2; Belongs to the peptidase S1 family. (262 aa)
	SLC8A1	Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
	SLC36A4	Solute carrier family 36 member 4. (504 aa)
	ATP1B2	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	CPB2	Carboxypeptidase B2. (423 aa)
	SLC3A2	Solute carrier family 3 member 2. (631 aa)
	COL6A5	Collagen type VI alpha 5 chain. (2608 aa)
	MME	Membrane metalloendopeptidase. (750 aa)
	COL5A1	Collagen type V alpha 1 chain. (1840 aa)
	SLC7A7	Solute carrier family 7 member 7. (511 aa)
	COL19A1	Collagen type XIX alpha 1 chain. (1141 aa)
	CELA1	Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (257 aa)
	COL6A1	Collagen type VI alpha 1 chain. (1028 aa)
	LOC105471423	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (262 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
	COL8A2	Collagen type VIII alpha 2 chain. (701 aa)
	COL9A2	Collagen type IX alpha 2 chain. (689 aa)
	COL7A1	Collagen type VII alpha 1 chain. (2944 aa)
	COL13A1	Collagen type XIII alpha 1 chain. (717 aa)
	MEP1A	Meprin A subunit. (746 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	COL22A1	Collagen type XXII alpha 1 chain. (1626 aa)
	KCNJ13	Potassium voltage-gated channel subfamily J member 13. (360 aa)
	CTRL	Chymotrypsin like; Belongs to the peptidase S1 family. (264 aa)
	CELA3B	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (270 aa)
	SLC9A5	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (896 aa)
	ENSMNEP00000037017	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (249 aa)
	C1QTNF7	C1q and TNF related 7. (298 aa)
	EMID1	EMI domain containing 1. (445 aa)
	LOC105491273	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (262 aa)
	FXYD2	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
	SLC8A3	Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
	SLC1A5	Amino acid transporter. (526 aa)
	COL27A1	Collagen type XXVII alpha 1 chain. (1857 aa)
	MEP1B	Meprin A subunit. (701 aa)
	COL12A1	Collagen type XII alpha 1 chain. (3063 aa)
	LOC105471238	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (257 aa)
	COL4A6	Collagen type IV alpha 6 chain. (1705 aa)
	SLC7A8	Solute carrier family 7 member 8. (535 aa)
	CPB1	Carboxypeptidase B1. (417 aa)
	CPA1	Carboxypeptidase A1. (419 aa)
	COL20A1	Uncharacterized protein. (1300 aa)
	OVCH2	Ovochymase 2 (gene/pseudogene); Belongs to the peptidase S1 family. (554 aa)
	MFF	Mitochondrial fission factor. (341 aa)
	CPA2	Carboxypeptidase A2. (421 aa)
	COL1A1	Collagen type I alpha 1 chain. (1464 aa)
	ACE2	Angiotensin-converting enzyme. (805 aa)
	COL24A1	Collagen type XXIV alpha 1 chain. (1714 aa)
	CLTRN	Collectrin domain-containing protein. (222 aa)
	OVCH1	Ovochymase 1; Belongs to the peptidase S1 family. (1126 aa)
	SLC7A10	Solute carrier family 7 member 10. (523 aa)
	ENSMNEP00000027279	Uncharacterized protein. (705 aa)
	KCNN4	Potassium calcium-activated channel subfamily N member 4. (427 aa)
	CPA6	Carboxypeptidase A6. (437 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	DPP4	ENSMNEP00000029823	ENSMNEP00000026084	Angiotensin-converting enzyme.	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.	0.984
ACE2	MEP1A	ENSMNEP00000029823	ENSMNEP00000039045	Angiotensin-converting enzyme.	Meprin A subunit.	0.933
ACE2	MEP1B	ENSMNEP00000029823	ENSMNEP00000035128	Angiotensin-converting enzyme.	Meprin A subunit.	0.929
ACE2	MME	ENSMNEP00000029823	ENSMNEP00000042845	Angiotensin-converting enzyme.	Membrane metalloendopeptidase.	0.947
ACE2	PRCP	ENSMNEP00000029823	ENSMNEP00000010868	Angiotensin-converting enzyme.	Prolylcarboxypeptidase.	0.941
ACE2	SLC1A5	ENSMNEP00000029823	ENSMNEP00000035291	Angiotensin-converting enzyme.	Amino acid transporter.	0.574
ACE2	SLC6A19	ENSMNEP00000029823	ENSMNEP00000000105	Angiotensin-converting enzyme.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.942
ACE2	XPNPEP2	ENSMNEP00000029823	ENSMNEP00000002491	Angiotensin-converting enzyme.	X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.	0.930
ATP1A1	ATP1A3	ENSMNEP00000022153	ENSMNEP00000016709	Sodium/potassium-transporting ATPase subunit alpha.	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.923
ATP1A1	ATP1A4	ENSMNEP00000022153	ENSMNEP00000017215	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.905
ATP1A1	ATP1B1	ENSMNEP00000022153	ENSMNEP00000038797	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.998
ATP1A1	ATP1B2	ENSMNEP00000022153	ENSMNEP00000044593	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.954
ATP1A1	ATP1B3	ENSMNEP00000022153	ENSMNEP00000023687	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.946
ATP1A1	ATP1B4	ENSMNEP00000022153	ENSMNEP00000024131	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.940
ATP1A1	ENSMNEP00000037017	ENSMNEP00000022153	ENSMNEP00000037017	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.771
ATP1A1	FXYD2	ENSMNEP00000022153	ENSMNEP00000035472	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.996
ATP1A2	ATP1A3	ENSMNEP00000024873	ENSMNEP00000016709	Sodium/potassium-transporting ATPase subunit alpha.	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.923
ATP1A2	ATP1A4	ENSMNEP00000024873	ENSMNEP00000017215	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.905
ATP1A2	ATP1B1	ENSMNEP00000024873	ENSMNEP00000038797	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.998
ATP1A2	ATP1B2	ENSMNEP00000024873	ENSMNEP00000044593	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.954