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ATP1A4 ATP1A4 ADCY3 ADCY3 ADCY2 ADCY2 ATP1B2 ATP1B2 LOC105477363 LOC105477363 LOC105463617 LOC105463617 SCTR SCTR ADCY5 ADCY5 ADCY6 ADCY6 PRKACA PRKACA SLC22A6 SLC22A6 SLC4A4 SLC4A4 SLC51A SLC51A CFTR CFTR ATP1B1 ATP1B1 SLC5A1 SLC5A1 ADCY4 ADCY4 SLC9A5 SLC9A5 ENSMNEP00000037017 ENSMNEP00000037017 EPHX1 EPHX1 AQP1 AQP1 AQP9 AQP9 FXYD2 FXYD2 SLC4A2 SLC4A2 NR0B2 NR0B2 ADCY8 ADCY8 CYP7A1 CYP7A1 SLCO1B3 SLCO1B3 SLC27A5 SLC27A5 PRKACB PRKACB SLC10A1 SLC10A1 SULT2A1 SULT2A1 SLC22A8 SLC22A8 LOC105477362 LOC105477362 UGT2A3 UGT2A3 ABCC2 ABCC2 SLC51B SLC51B SCARB1 SCARB1 CA2 CA2 HMGCR HMGCR BAAT BAAT LOC105477366 LOC105477366 SLC25A39 SLC25A39 ATP1A2 ATP1A2 ATP1B4 ATP1B4 ABCG2 ABCG2 ATP1B3 ATP1B3 ABCG5 ABCG5 SLC2A1 SLC2A1 PTRHD1 PTRHD1 ATP1A1 ATP1A1 SLC4A5 SLC4A5 ABCB4 ABCB4 GNAS GNAS ABCB11 ABCB11 UGT2A1 UGT2A1 ENSMNEP00000019397 ENSMNEP00000019397 SLC22A7 SLC22A7 SLCO1B1 SLCO1B1 SLC25A40 SLC25A40 ATP1A3 ATP1A3 ABCC3 ABCC3 SLC5A4 SLC5A4 ABCC4 ABCC4 AQP4 AQP4 UGT1A1 UGT1A1 SLC10A2 SLC10A2 RXRA RXRA NCEH1 NCEH1 NR1H4 NR1H4 ADCY1 ADCY1 ADCY7 ADCY7 SLCO1A2 SLCO1A2 ABCG8 ABCG8 MINDY4 MINDY4 SLC22A1 SLC22A1 AQP8 AQP8 ADCY9 ADCY9 SLC9A1 SLC9A1 SCT SCT LOC105470579 LOC105470579 SLC9A3 SLC9A3 LDLR LDLR KCNN2 KCNN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
LOC105477363UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
LOC105463617UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (410 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1214 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
SLC22A6Solute carrier family 22 member 6. (550 aa)
SLC4A4Anion exchange protein. (1125 aa)
SLC51ASolute carrier family 51 alpha subunit. (340 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1481 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
SLC5A1Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (663 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (896 aa)
ENSMNEP00000037017Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (249 aa)
EPHX1Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (477 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
AQP9Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
SLC4A2Anion exchange protein. (1249 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
SLCO1B3Solute carrier organic anion transporter family member. (707 aa)
SLC27A5Solute carrier family 27 member 5. (690 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
SLC10A1Solute carrier family 10 member 1. (349 aa)
SULT2A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (285 aa)
SLC22A8Solute carrier family 22 member 8. (542 aa)
LOC105477362UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
UGT2A3UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (527 aa)
ABCC2ATP binding cassette subfamily C member 2. (1545 aa)
SLC51BSolute carrier family 51 beta subunit. (130 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (553 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa)
BAATBile acid-CoA:amino acid N-acyltransferase. (418 aa)
LOC105477366UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
SLC25A39Solute carrier family 25 member 39; Belongs to the mitochondrial carrier (TC 2.A.29) family. (366 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
ABCG2ABC transporter domain-containing protein. (655 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
ABCG5ATP binding cassette subfamily G member 5. (651 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
SLC4A5Anion exchange protein. (1136 aa)
ABCB4ATP binding cassette subfamily B member 4. (1286 aa)
GNASGNAS complex locus. (1007 aa)
ABCB11ATP binding cassette subfamily B member 11. (1323 aa)
UGT2A1UDP glucuronosyltransferase family 2 member A1 complex locus; Belongs to the UDP-glycosyltransferase family. (693 aa)
ENSMNEP00000019397Uncharacterized protein. (279 aa)
SLC22A7Solute carrier family 22 member 7. (548 aa)
SLCO1B1Solute carrier organic anion transporter family member. (682 aa)
SLC25A40Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
ATP1A3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1229 aa)
ABCC3ATP binding cassette subfamily C member 3. (1526 aa)
SLC5A4Solute carrier family 5 member 4; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (659 aa)
ABCC4ATP binding cassette subfamily C member 4. (1325 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
UGT1A1UDP glucuronosyltransferase family 1 member A1; Belongs to the UDP-glycosyltransferase family. (570 aa)
SLC10A2Solute carrier family 10 member 2. (348 aa)
RXRARetinoid X receptor alpha. (523 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (408 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1088 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
SLCO1A2Solute carrier organic anion transporter family member. (670 aa)
ABCG8ATP binding cassette subfamily G member 8. (673 aa)
MINDY4MINDY lysine 48 deubiquitinase 4. (757 aa)
SLC22A1Solute carrier family 22 member 1. (554 aa)
AQP8Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
SCTSecretin. (117 aa)
LOC105470579Uncharacterized protein. (245 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (523 aa)
LDLRLow density lipoprotein receptor. (783 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (844 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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