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RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) | ||||
ENSMNEP00000000821 | Ig-like domain-containing protein. (143 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (758 aa) | ||||
ENSMNEP00000001351 | Ig-like domain-containing protein. (151 aa) | ||||
TLR2 | Toll-like receptor. (784 aa) | ||||
JAK1 | Tyrosine-protein kinase. (1159 aa) | ||||
HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa) | ||||
ENSMNEP00000002245 | Ig-like domain-containing protein. (232 aa) | ||||
TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) | ||||
HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) | ||||
ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) | ||||
ENSMNEP00000004521 | Ig-like domain-containing protein. (230 aa) | ||||
LOC105470433 | MHC class II antigen. (260 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (717 aa) | ||||
ENSMNEP00000004839 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (433 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) | ||||
CYBB | Cytochrome b-245 beta chain. (614 aa) | ||||
ENSMNEP00000009424 | Ig-like domain-containing protein. (161 aa) | ||||
ENSMNEP00000010506 | Ig-like domain-containing protein. (142 aa) | ||||
HLA-DPB1 | Major histocompatibility complex, class II, DP beta 1. (268 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (968 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (366 aa) | ||||
ENSMNEP00000012002 | TNF receptor-associated factor. (457 aa) | ||||
NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1063 aa) | ||||
ENSMNEP00000013480 | Tr-type G domain-containing protein. (409 aa) | ||||
CR1L | Complement C3b/C4b receptor 1 like. (569 aa) | ||||
ITGB2 | Integrin beta. (921 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1139 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
NCF2 | Neutrophil cytosolic factor 2. (526 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
ELK1 | ETS transcription factor ELK1. (428 aa) | ||||
HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa) | ||||
NCF1 | Neutrophil cytosolic factor 1. (390 aa) | ||||
NCF4 | Neutrophil cytosolic factor 4. (339 aa) | ||||
ENSMNEP00000018421 | Tr-type G domain-containing protein. (113 aa) | ||||
ENSMNEP00000018709 | Ig-like domain-containing protein. (122 aa) | ||||
PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) | ||||
FCGR1A | Uncharacterized protein. (357 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) | ||||
LOC105470432 | Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) | ||||
ENSMNEP00000020833 | Ig-like domain-containing protein. (145 aa) | ||||
ENSMNEP00000021289 | Ig-like domain-containing protein. (182 aa) | ||||
IFNGR2 | Interferon gamma receptor 2. (312 aa) | ||||
NOXA1 | NADPH oxidase activator 1. (476 aa) | ||||
FCGR2B | Uncharacterized protein. (313 aa) | ||||
EEF1A1 | Uncharacterized protein. (330 aa) | ||||
ENSMNEP00000025520 | Ig-like domain-containing protein. (194 aa) | ||||
CR1 | Complement C3b/C4b receptor 1 (Knops blood group). (1649 aa) | ||||
LOC105477893 | Uncharacterized protein. (1747 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa) | ||||
HLA-DQA1 | Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (267 aa) | ||||
C3 | Complement C3. (1642 aa) | ||||
LOC105498220 | Uncharacterized protein. (342 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (317 aa) | ||||
IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) | ||||
IL1A | Interleukin-1; Belongs to the IL-1 family. (224 aa) | ||||
ENSMNEP00000033999 | Tr-type G domain-containing protein. (422 aa) | ||||
CYBA | Cytochrome b-245 alpha chain. (197 aa) | ||||
ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1153 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (365 aa) | ||||
TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa) | ||||
ENSMNEP00000035156 | Tr-type G domain-containing protein. (113 aa) | ||||
HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa) | ||||
IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) | ||||
FAM229A | Family with sequence similarity 229 member A. (127 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) | ||||
ENSMNEP00000038649 | Ig-like domain-containing protein. (235 aa) | ||||
TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) | ||||
IFNGR1 | Interferon gamma receptor 1. (488 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) | ||||
HLA-DOB | Major histocompatibility complex, class II, DO beta. (285 aa) | ||||
ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) | ||||
ENSMNEP00000042851 | Tr-type G domain-containing protein. (113 aa) | ||||
LOC105474413 | Ig-like domain-containing protein. (295 aa) | ||||
LOC105474426 | Ig-like domain-containing protein. (263 aa) | ||||
NFKBIB | NFKB inhibitor beta. (356 aa) | ||||
EEF1A2 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa) | ||||
MARCKSL1 | MARCKS like 1. (195 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) |