STRINGSTRING
LOC105495842 LOC105495842 CAMK2D CAMK2D PPP1R14B PPP1R14B LSP1 LSP1 LOC105480535 LOC105480535 MAPK14 MAPK14 IFNG IFNG NFYB NFYB ATP6V0D2 ATP6V0D2 CAMP CAMP BAD BAD ITGAX ITGAX LOC105474426 LOC105474426 TCIRG1 TCIRG1 CORO1B CORO1B CAMK2A CAMK2A LOC105474413 LOC105474413 CALM1 CALM1 IL12A IL12A ENSMNEP00000042187 ENSMNEP00000042187 ENSMNEP00000041867 ENSMNEP00000041867 PPP3R1 PPP3R1 HLA-DOB HLA-DOB LOC105498430 LOC105498430 TGFB3 TGFB3 CREBBP CREBBP TGFB2 TGFB2 ENSMNEP00000041024 ENSMNEP00000041024 MAPK10 MAPK10 EP300 EP300 PPP3CC PPP3CC EFCAB3 EFCAB3 IL18 IL18 TGFB1 TGFB1 MAPK12 MAPK12 IFNGR1 IFNGR1 AKT3 AKT3 ENSMNEP00000038649 ENSMNEP00000038649 RHOA RHOA TRAF6 TRAF6 RIPK2 RIPK2 IFNA14 IFNA14 IL10 IL10 LAMP1 LAMP1 MAPK9 MAPK9 CAMK2G CAMK2G BPI BPI BCL10 BCL10 MALT1 MALT1 C7orf31 C7orf31 ENSMNEP00000035631 ENSMNEP00000035631 HLA-DPA1 HLA-DPA1 CYCS CYCS TLR4 TLR4 MAPK13 MAPK13 CLEC7A CLEC7A RAF1 RAF1 ITGAM ITGAM ATP6AP1 ATP6AP1 ENSMNEP00000034158 ENSMNEP00000034158 IL1A IL1A SPHK2 SPHK2 IL1B IL1B IRAK4 IRAK4 CASP8 CASP8 ARSI ARSI MYD88 MYD88 PLK3 PLK3 CAMK2B CAMK2B LOC105498220 LOC105498220 CIITA CIITA RAB5A RAB5A C3 C3 ATP6V0A2 ATP6V0A2 CORO1C CORO1C HLA-DQA1 HLA-DQA1 CALM3 CALM3 LOC105498418 LOC105498418 TNF TNF FADD FADD IFNB1 IFNB1 AKT2 AKT2 SYK SYK RELA RELA LOC105477893 LOC105477893 PPP3CA PPP3CA CALM2 CALM2 RHOC RHOC CASP10 CASP10 CD74 CD74 AKT1 AKT1 RFX5 RFX5 CR1 CR1 ENSMNEP00000025520 ENSMNEP00000025520 ATP6V0C ATP6V0C IL23A IL23A CALML6 CALML6 PVALEF PVALEF FCGR2B FCGR2B PIK3C3 PIK3C3 ATP6V1H ATP6V1H CORO1A CORO1A BCL2 BCL2 ENSMNEP00000023427 ENSMNEP00000023427 BAX BAX CLEC4E CLEC4E IL10RA IL10RA IFNGR2 IFNGR2 TIRAP TIRAP CTSS CTSS ENSMNEP00000022061 ENSMNEP00000022061 FCER1G FCER1G LAMP2 LAMP2 ENSMNEP00000021289 ENSMNEP00000021289 LBP LBP HSPA9 HSPA9 ENSMNEP00000020833 ENSMNEP00000020833 CLEC4A CLEC4A LOC105470432 LOC105470432 ENSMNEP00000019824 ENSMNEP00000019824 IL12B IL12B ARHGEF12 ARHGEF12 FCGR1A FCGR1A RAB7A RAB7A ENSMNEP00000018709 ENSMNEP00000018709 CALML4 CALML4 CD209 CD209 PPP3CB PPP3CB HLA-DMA HLA-DMA PLK5 PLK5 ENSMNEP00000017348 ENSMNEP00000017348 NOD2 NOD2 CASP9 CASP9 CLEC4G CLEC4G ENSMNEP00000016414 ENSMNEP00000016414 MRC2 MRC2 PLA2R1 PLA2R1 CORO6 CORO6 BID BID CYP27B1 CYP27B1 MAPK3 MAPK3 CD14 CD14 ATP6V0A1 ATP6V0A1 ENSMNEP00000015249 ENSMNEP00000015249 ENSMNEP00000014992 ENSMNEP00000014992 ATP6V0A4 ATP6V0A4 JAK2 JAK2 ITGB2 ITGB2 CR1L CR1L ENSMNEP00000013313 ENSMNEP00000013313 NOS2 NOS2 ENSMNEP00000013207 ENSMNEP00000013207 ENSMNEP00000013195 ENSMNEP00000013195 CARD9 CARD9 RAB17 RAB17 MAPK8 MAPK8 APAF1 APAF1 IL10RB IL10RB ENSMNEP00000012002 ENSMNEP00000012002 CREB1 CREB1 MAPK11 MAPK11 MAPK1 MAPK1 ATP6V0D1 ATP6V0D1 TNFRSF1A TNFRSF1A ENSMNEP00000011545 ENSMNEP00000011545 ANKRA2 ANKRA2 NFKB1 NFKB1 HLA-DPB1 HLA-DPB1 MRC1 MRC1 ENSMNEP00000010506 ENSMNEP00000010506 VDR VDR KSR1 KSR1 ENSMNEP00000009424 ENSMNEP00000009424 ENSMNEP00000008172 ENSMNEP00000008172 RFXAP RFXAP NFYC NFYC SRC SRC CEBPG CEBPG NFYA NFYA LOC105492342 LOC105492342 RFXANK RFXANK ENSMNEP00000005419 ENSMNEP00000005419 ATP6V0B ATP6V0B LOC105477715 LOC105477715 IRAK1 IRAK1 LOC105470433 LOC105470433 IRAK2 IRAK2 LOC105495023 LOC105495023 ENSMNEP00000004521 ENSMNEP00000004521 HLA-DRA HLA-DRA LOC105477037 LOC105477037 ENSMNEP00000004019 ENSMNEP00000004019 TRADD TRADD LOC105486922 LOC105486922 SPHK1 SPHK1 TLR10 TLR10 ENSMNEP00000002245 ENSMNEP00000002245 HLA-DOA HLA-DOA JAK1 JAK1 CALML3 CALML3 CEBPB CEBPB TLR2 TLR2 ENSMNEP00000001351 ENSMNEP00000001351 ENSMNEP00000001346 ENSMNEP00000001346 LOC105497820 LOC105497820 LOC105491771 LOC105491771 RAB5B RAB5B STAT1 STAT1 IFNA6 IFNA6 TLR1 TLR1 ENSMNEP00000000821 ENSMNEP00000000821 LOC105487609 LOC105487609 IL6 IL6 EEA1 EEA1 EFCAB13 EFCAB13 RAB5C RAB5C ENSMNEP00000000021 ENSMNEP00000000021
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105495842Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
PPP1R14BUncharacterized protein. (208 aa)
LSP1Lymphocyte specific protein 1. (454 aa)
LOC105480535TIR domain-containing protein. (1033 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
NFYBCBFD_NFYB_HMF domain-containing protein. (208 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (348 aa)
CAMPCathelicidin antimicrobial peptide. (173 aa)
BADBCL2 associated agonist of cell death. (167 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1163 aa)
LOC105474426Ig-like domain-containing protein. (263 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (489 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
LOC105474413Ig-like domain-containing protein. (295 aa)
CALM1Calmodulin 1. (149 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
ENSMNEP00000042187CBFD_NFYB_HMF domain-containing protein. (292 aa)
ENSMNEP00000041867Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa)
PPP3R1Uncharacterized protein. (189 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (285 aa)
LOC105498430Uncharacterized protein. (189 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CREBBPCREB binding protein. (2442 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ENSMNEP00000041024Uncharacterized protein. (82 aa)
MAPK10Mitogen-activated protein kinase. (489 aa)
EP300E1A binding protein p300. (2397 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
EFCAB3EF-hand calcium binding domain 3. (488 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
IFNGR1Interferon gamma receptor 1. (488 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSMNEP00000038649Ig-like domain-containing protein. (235 aa)
RHOARas homolog family member A. (193 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
IFNA14Interferon alpha 14. (137 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
LAMP1Lysosomal associated membrane protein 1. (416 aa)
MAPK9Mitogen-activated protein kinase 9. (354 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (556 aa)
BPIBactericidal permeability increasing protein. (511 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
MALT1MALT1 paracaspase. (824 aa)
C7orf31Chromosome 7 open reading frame 31. (590 aa)
ENSMNEP00000035631Uncharacterized protein. (96 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
CLEC7AC-type lectin domain containing 7A. (247 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1153 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (472 aa)
ENSMNEP00000034158CBFD_NFYB_HMF domain-containing protein. (202 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (224 aa)
SPHK2Sphingosine kinase 2. (653 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (487 aa)
ARSIArylsulfatase family member I. (569 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
PLK3Serine/threonine-protein kinase PLK. (608 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
LOC105498220Uncharacterized protein. (342 aa)
CIITAClass II major histocompatibility complex transactivator. (1235 aa)
RAB5AUncharacterized protein. (215 aa)
C3Complement C3. (1642 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (524 aa)
HLA-DQA1Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (267 aa)
CALM3Calmodulin 3. (149 aa)
LOC105498418Uncharacterized protein. (190 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
IFNB1Interferon beta 1. (187 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SYKTyrosine-protein kinase. (629 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
LOC105477893Uncharacterized protein. (1747 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
CALM2Calmodulin 1; Belongs to the calmodulin family. (149 aa)
RHOCRas homolog family member C. (193 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (520 aa)
CD74CD74 molecule. (294 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
RFX5Regulatory factor X5. (620 aa)
CR1Complement C3b/C4b receptor 1 (Knops blood group). (1649 aa)
ENSMNEP00000025520Ig-like domain-containing protein. (194 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
CALML6Calmodulin like 6. (181 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
FCGR2BUncharacterized protein. (313 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (496 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSMNEP00000023427Uncharacterized protein. (198 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
CLEC4EC-type lectin domain family 4 member E. (219 aa)
IL10RAInterleukin 10 receptor subunit alpha. (580 aa)
IFNGR2Interferon gamma receptor 2. (312 aa)
TIRAPTIR domain containing adaptor protein. (234 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (331 aa)
ENSMNEP00000022061Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (588 aa)
FCER1GFc fragment of IgE receptor Ig. (112 aa)
LAMP2Lysosomal associated membrane protein 2. (411 aa)
ENSMNEP00000021289Ig-like domain-containing protein. (182 aa)
LBPLipopolysaccharide binding protein. (481 aa)
HSPA9Uncharacterized protein; Belongs to the heat shock protein 70 family. (679 aa)
ENSMNEP00000020833Ig-like domain-containing protein. (145 aa)
CLEC4AC-type lectin domain family 4 member A. (237 aa)
LOC105470432Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa)
ENSMNEP00000019824Uncharacterized protein. (194 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1484 aa)
FCGR1AUncharacterized protein. (357 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
ENSMNEP00000018709Ig-like domain-containing protein. (122 aa)
CALML4Calmodulin like 4. (193 aa)
CD209CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity). (413 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa)
PLK5Polo like kinase 5. (299 aa)
ENSMNEP00000017348Uncharacterized protein. (191 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1044 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (421 aa)
CLEC4GC-type lectin domain family 4 member G. (293 aa)
ENSMNEP00000016414Uncharacterized protein; Belongs to the calmodulin family. (179 aa)
MRC2Mannose receptor C type 2. (1479 aa)
PLA2R1Phospholipase A2 receptor 1. (1466 aa)
CORO6Coronin; Belongs to the WD repeat coronin family. (472 aa)
BIDBH3 interacting domain death agonist. (266 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (780 aa)
ENSMNEP00000015249Uncharacterized protein. (201 aa)
ENSMNEP00000014992Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (508 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (836 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
ITGB2Integrin beta. (921 aa)
CR1LComplement C3b/C4b receptor 1 like. (569 aa)
ENSMNEP00000013313Uncharacterized protein. (152 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1063 aa)
ENSMNEP00000013207Uncharacterized protein. (372 aa)
ENSMNEP00000013195Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (520 aa)
CARD9Caspase recruitment domain family member 9. (535 aa)
RAB17RAB17, member RAS oncogene family. (212 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
ENSMNEP00000012002TNF receptor-associated factor. (457 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (392 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
ENSMNEP00000011545Uncharacterized protein. (81 aa)
ANKRA2Ankyrin repeat family A member 2. (313 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (268 aa)
MRC1Mannose receptor C-type 1. (1456 aa)
ENSMNEP00000010506Ig-like domain-containing protein. (142 aa)
VDRVitamin D receptor. (477 aa)
KSR1Kinase suppressor of ras 1. (932 aa)
ENSMNEP00000009424Ig-like domain-containing protein. (161 aa)
ENSMNEP00000008172Uncharacterized protein. (365 aa)
RFXAPRegulatory factor X associated protein. (272 aa)
NFYCNuclear transcription factor Y subunit gamma. (439 aa)
SRCTyrosine-protein kinase. (644 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
NFYANuclear transcription factor Y subunit alpha. (347 aa)
LOC105492342Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
RFXANKRegulatory factor X associated ankyrin containing protein. (260 aa)
ENSMNEP00000005419Uncharacterized protein. (114 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (255 aa)
LOC105477715Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (717 aa)
LOC105470433MHC class II antigen. (260 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (625 aa)
LOC105495023Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa)
ENSMNEP00000004521Ig-like domain-containing protein. (230 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
LOC105477037Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMNEP00000004019Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
LOC105486922Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
SPHK1Sphingosine kinase 1. (470 aa)
TLR10Toll like receptor 10; Belongs to the Toll-like receptor family. (811 aa)
ENSMNEP00000002245Ig-like domain-containing protein. (232 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
CEBPBCCAAT/enhancer-binding protein. (344 aa)
TLR2Toll-like receptor. (784 aa)
ENSMNEP00000001351Ig-like domain-containing protein. (151 aa)
ENSMNEP00000001346Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (251 aa)
LOC105497820Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105491771Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
RAB5BRAB5B, member RAS oncogene family. (221 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
IFNA6Interferon alpha 6. (190 aa)
TLR1Toll-like receptor. (786 aa)
ENSMNEP00000000821Ig-like domain-containing protein. (143 aa)
LOC105487609Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
IL6Interleukin 6. (214 aa)
EEA1Early endosome antigen 1. (1405 aa)
EFCAB13EF-hand calcium binding domain 13. (925 aa)
RAB5CRAB5C, member RAS oncogene family. (249 aa)
ENSMNEP00000000021V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (138 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: low (12%) [HD]