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MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) | ||||
ENSMNEP00000024827 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (269 aa) | ||||
YWHAQ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa) | ||||
EGR3 | Early growth response 3. (387 aa) | ||||
MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (374 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (384 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (239 aa) | ||||
ENSMNEP00000023427 | Uncharacterized protein. (198 aa) | ||||
CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (203 aa) | ||||
ENSMNEP00000022738 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (220 aa) | ||||
MMP9 | Matrix metallopeptidase 9. (694 aa) | ||||
CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) | ||||
TIRAP | TIR domain containing adaptor protein. (234 aa) | ||||
NFATC2 | Nuclear factor of activated T cells 2. (921 aa) | ||||
CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) | ||||
SMAD4 | Mothers against decapentaplegic homolog. (552 aa) | ||||
ENSMNEP00000013313 | Uncharacterized protein. (152 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1139 aa) | ||||
TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa) | ||||
DDB1 | Damage specific DNA binding protein 1. (1147 aa) | ||||
DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
BID | BH3 interacting domain death agonist. (266 aa) | ||||
ENSMNEP00000016378 | Protein kinase domain-containing protein. (652 aa) | ||||
ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) | ||||
CASP12 | Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (408 aa) | ||||
ELK1 | ETS transcription factor ELK1. (428 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (421 aa) | ||||
STAT5A | Signal transducer and activator of transcription. (794 aa) | ||||
STAT5B | Signal transducer and activator of transcription. (783 aa) | ||||
IFIH1 | Interferon induced with helicase C domain 1. (1025 aa) | ||||
ENSMNEP00000018013 | Uncharacterized protein. (243 aa) | ||||
MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (425 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (660 aa) | ||||
ENSMNEP00000019155 | Interfer-bind domain-containing protein. (338 aa) | ||||
ENSMNEP00000019824 | Uncharacterized protein. (194 aa) | ||||
ENSMNEP00000020290 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (125 aa) | ||||
STAT4 | Signal transducer and activator of transcription. (748 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
STAT2 | Signal transducer and activator of transcription. (852 aa) | ||||
ENSMNEP00000020581 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (208 aa) | ||||
E2F1 | E2F transcription factor 1. (437 aa) | ||||
SRC | Tyrosine-protein kinase. (644 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1. (361 aa) | ||||
CCNE1 | Cyclin E1; Belongs to the cyclin family. (407 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) | ||||
FAS | Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa) | ||||
PIK3R2 | Uncharacterized protein. (668 aa) | ||||
CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) | ||||
ATF6B | Activating transcription factor 6 beta. (710 aa) | ||||
IRF7 | Interferon regulatory factor 7. (504 aa) | ||||
ENSMNEP00000009204 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (224 aa) | ||||
DDB2 | Damage specific DNA binding protein 2. (427 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (968 aa) | ||||
ENSMNEP00000011545 | Uncharacterized protein. (81 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (366 aa) | ||||
CREB1 | cAMP responsive element binding protein 1. (341 aa) | ||||
RB1 | RB transcriptional corepressor 1. (928 aa) | ||||
ENSMNEP00000012002 | TNF receptor-associated factor. (457 aa) | ||||
NFATC4 | Nuclear factor of activated T cells 4. (961 aa) | ||||
APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) | ||||
TMED7 | Transmembrane p24 trafficking protein 7. (224 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (463 aa) | ||||
TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
CREB3L4 | cAMP responsive element binding protein 3 like 4. (422 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) | ||||
EP300 | E1A binding protein p300. (2397 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (489 aa) | ||||
TBK1 | TANK binding kinase 1. (729 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
CREBBP | CREB binding protein. (2442 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) | ||||
LOC105498430 | Uncharacterized protein. (189 aa) | ||||
E2F3 | E2F transcription factor 3. (465 aa) | ||||
ENSMNEP00000041867 | Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa) | ||||
HSPG2 | Heparan sulfate proteoglycan 2. (4392 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa) | ||||
MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
CREB3 | cAMP responsive element binding protein 3. (372 aa) | ||||
CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) | ||||
BAD | BCL2 associated agonist of cell death. (167 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
STAT6 | Signal transducer and activator of transcription. (847 aa) | ||||
ENSMNEP00000045253 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (234 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (189 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
CSDE1 | Cold shock domain containing E1. (844 aa) | ||||
BIRC5 | Uncharacterized protein. (147 aa) | ||||
PPP1R14B | Uncharacterized protein. (208 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) | ||||
IL6 | Interleukin 6. (214 aa) | ||||
LOC105487609 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
ERAS | ES cell expressed Ras. (233 aa) | ||||
IFNA6 | Interferon alpha 6. (190 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (758 aa) | ||||
LOC105491771 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
LOC105497820 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) | ||||
TLR2 | Toll-like receptor. (784 aa) | ||||
JAK1 | Tyrosine-protein kinase. (1159 aa) | ||||
MAVS | Mitochondrial antiviral signaling protein. (541 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) | ||||
LOC105495842 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
ENSMNEP00000002161 | Uncharacterized protein. (142 aa) | ||||
ENSMNEP00000002263 | Uncharacterized protein. (329 aa) | ||||
CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) | ||||
NFATC1 | Nuclear factor of activated T cells 1. (988 aa) | ||||
TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) | ||||
LOC105486922 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
ENSMNEP00000004019 | Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa) | ||||
LOC105477037 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) | ||||
LOC105495023 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (717 aa) | ||||
TICAM2 | Toll like receptor adaptor molecule 2. (235 aa) | ||||
LOC105477715 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) | ||||
NFATC3 | Nuclear factor of activated T cells 3. (1075 aa) | ||||
LOC105492342 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (763 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) | ||||
EGR2 | Early growth response 2. (426 aa) | ||||
DDX58 | DExD/H-box helicase 58. (925 aa) | ||||
IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) | ||||
IFNA14 | Interferon alpha 14. (137 aa) | ||||
ENSMNEP00000036686 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (234 aa) | ||||
MAPK9 | Mitogen-activated protein kinase 9. (354 aa) | ||||
YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (257 aa) | ||||
E2F2 | E2F transcription factor 2. (439 aa) | ||||
CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
C7orf31 | Chromosome 7 open reading frame 31. (590 aa) | ||||
CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (365 aa) | ||||
JAK3 | Tyrosine-protein kinase. (1088 aa) | ||||
CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) | ||||
ATP6AP1 | ATPase H+ transporting accessory protein 1. (472 aa) | ||||
FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) | ||||
IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) | ||||
VDAC3 | Voltage dependent anion channel 3. (284 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (487 aa) | ||||
CREB3L3 | cAMP responsive element binding protein 3 like 3. (446 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (317 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1345 aa) | ||||
ENSMNEP00000031713 | 14_3_3 domain-containing protein. (92 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (270 aa) | ||||
TYK2 | Tyrosine-protein kinase. (1190 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) | ||||
SLC10A1 | Solute carrier family 10 member 1. (349 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
TICAM1 | Toll like receptor adaptor molecule 1. (519 aa) | ||||
ENSMNEP00000029305 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (214 aa) | ||||
LOC105498418 | Uncharacterized protein. (190 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
IFNB1 | Interferon beta 1. (187 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) | ||||
ATF4 | Activating transcription factor 4. (351 aa) | ||||
IRF3 | Interferon regulatory factor 3. (422 aa) | ||||
ENSMNEP00000027902 | Protein kinase domain-containing protein. (365 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
CASP10 | Caspase 10; Belongs to the peptidase C14A family. (520 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |