STRINGSTRING
MAP2K6 MAP2K6 ENSMNEP00000024827 ENSMNEP00000024827 YWHAQ YWHAQ EGR3 EGR3 MAP2K4 MAP2K4 MAP2K7 MAP2K7 BCL2 BCL2 ENSMNEP00000023427 ENSMNEP00000023427 CCNE2 CCNE2 BAX BAX ENSMNEP00000022738 ENSMNEP00000022738 MMP9 MMP9 CXCL8 CXCL8 TIRAP TIRAP NFATC2 NFATC2 CREB5 CREB5 TRAF6 TRAF6 SMAD4 SMAD4 ENSMNEP00000013313 ENSMNEP00000013313 JAK2 JAK2 TLR3 TLR3 FOS FOS TGFBR1 TGFBR1 DDB1 DDB1 DDX3X DDX3X MAPK3 MAPK3 PCNA PCNA BID BID ENSMNEP00000016378 ENSMNEP00000016378 ARAF ARAF CASP12 CASP12 ELK1 ELK1 CASP9 CASP9 STAT5A STAT5A STAT5B STAT5B IFIH1 IFIH1 ENSMNEP00000018013 ENSMNEP00000018013 MAP2K3 MAP2K3 PTK2B PTK2B SMAD3 SMAD3 STAT3 STAT3 ENSMNEP00000019155 ENSMNEP00000019155 ENSMNEP00000019824 ENSMNEP00000019824 ENSMNEP00000020290 ENSMNEP00000020290 STAT4 STAT4 PIK3CA PIK3CA STAT2 STAT2 ENSMNEP00000020581 ENSMNEP00000020581 E2F1 E2F1 SRC SRC MAP2K1 MAP2K1 CCNE1 CCNE1 SOS2 SOS2 FAS FAS PIK3R2 PIK3R2 CCNA1 CCNA1 ATF6B ATF6B IRF7 IRF7 ENSMNEP00000009204 ENSMNEP00000009204 DDB2 DDB2 NFKB1 NFKB1 ENSMNEP00000011545 ENSMNEP00000011545 MAPK1 MAPK1 MAPK11 MAPK11 CREB1 CREB1 RB1 RB1 ENSMNEP00000012002 ENSMNEP00000012002 NFATC4 NFATC4 APAF1 APAF1 CHUK CHUK TMED7 TMED7 MAPK8 MAPK8 PIK3R3 PIK3R3 TAB1 TAB1 AKT3 AKT3 MAPK12 MAPK12 CREB3L4 CREB3L4 TGFB1 TGFB1 EP300 EP300 MAPK10 MAPK10 TBK1 TBK1 TGFB2 TGFB2 CREBBP CREBBP TGFB3 TGFB3 LOC105498430 LOC105498430 E2F3 E2F3 ENSMNEP00000041867 ENSMNEP00000041867 HSPG2 HSPG2 SOS1 SOS1 MAP2K2 MAP2K2 CREB3 CREB3 CDK2 CDK2 BAD BAD NRAS NRAS STAT6 STAT6 ENSMNEP00000045253 ENSMNEP00000045253 KRAS KRAS MAPK14 MAPK14 CSDE1 CSDE1 BIRC5 BIRC5 PPP1R14B PPP1R14B IKBKG IKBKG PIK3CB PIK3CB IL6 IL6 LOC105487609 LOC105487609 ERAS ERAS IFNA6 IFNA6 STAT1 STAT1 LOC105491771 LOC105491771 LOC105497820 LOC105497820 TRAF3 TRAF3 TLR2 TLR2 JAK1 JAK1 MAVS MAVS CDKN1A CDKN1A LOC105495842 LOC105495842 ENSMNEP00000002161 ENSMNEP00000002161 ENSMNEP00000002263 ENSMNEP00000002263 CCNA2 CCNA2 NFATC1 NFATC1 TAB2 TAB2 LOC105486922 LOC105486922 ENSMNEP00000004019 ENSMNEP00000004019 LOC105477037 LOC105477037 MYC MYC LOC105495023 LOC105495023 IRAK1 IRAK1 TICAM2 TICAM2 LOC105477715 LOC105477715 NFATC3 NFATC3 LOC105492342 LOC105492342 BRAF BRAF PRKCB PRKCB EGR2 EGR2 DDX58 DDX58 IKBKE IKBKE IFNA14 IFNA14 ENSMNEP00000036686 ENSMNEP00000036686 MAPK9 MAPK9 YWHAZ YWHAZ E2F2 E2F2 CREB3L1 CREB3L1 TGFBR2 TGFBR2 C7orf31 C7orf31 CYCS CYCS TLR4 TLR4 MAPK13 MAPK13 JAK3 JAK3 CREB3L2 CREB3L2 RAF1 RAF1 ATP6AP1 ATP6AP1 FASLG FASLG IKBKB IKBKB IRAK4 IRAK4 VDAC3 VDAC3 CASP8 CASP8 CREB3L3 CREB3L3 NFKBIA NFKBIA MAP3K7 MAP3K7 MYD88 MYD88 HRAS HRAS MAP3K1 MAP3K1 ENSMNEP00000031713 ENSMNEP00000031713 PIK3CD PIK3CD TP53 TP53 TYK2 TYK2 YWHAB YWHAB SLC10A1 SLC10A1 PIK3R1 PIK3R1 TICAM1 TICAM1 ENSMNEP00000029305 ENSMNEP00000029305 LOC105498418 LOC105498418 TNF TNF ATF2 ATF2 FADD FADD IFNB1 IFNB1 AKT2 AKT2 PRKCG PRKCG PRKCA PRKCA RELA RELA ATF4 ATF4 IRF3 IRF3 ENSMNEP00000027902 ENSMNEP00000027902 GRB2 GRB2 CASP10 CASP10 AKT1 AKT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ENSMNEP0000002482714_3_3 domain-containing protein; Belongs to the 14-3-3 family. (269 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa)
EGR3Early growth response 3. (387 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (374 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (384 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSMNEP00000023427Uncharacterized protein. (198 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
ENSMNEP0000002273814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (220 aa)
MMP9Matrix metallopeptidase 9. (694 aa)
CXCL8Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
TIRAPTIR domain containing adaptor protein. (234 aa)
NFATC2Nuclear factor of activated T cells 2. (921 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ENSMNEP00000013313Uncharacterized protein. (152 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
BIDBH3 interacting domain death agonist. (266 aa)
ENSMNEP00000016378Protein kinase domain-containing protein. (652 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
CASP12Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (408 aa)
ELK1ETS transcription factor ELK1. (428 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (421 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
STAT5BSignal transducer and activator of transcription. (783 aa)
IFIH1Interferon induced with helicase C domain 1. (1025 aa)
ENSMNEP00000018013Uncharacterized protein. (243 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
STAT3Signal transducer and activator of transcription. (660 aa)
ENSMNEP00000019155Interfer-bind domain-containing protein. (338 aa)
ENSMNEP00000019824Uncharacterized protein. (194 aa)
ENSMNEP0000002029014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (125 aa)
STAT4Signal transducer and activator of transcription. (748 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
STAT2Signal transducer and activator of transcription. (852 aa)
ENSMNEP0000002058114_3_3 domain-containing protein; Belongs to the 14-3-3 family. (208 aa)
E2F1E2F transcription factor 1. (437 aa)
SRCTyrosine-protein kinase. (644 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (361 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (407 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
FASTumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa)
PIK3R2Uncharacterized protein. (668 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
ATF6BActivating transcription factor 6 beta. (710 aa)
IRF7Interferon regulatory factor 7. (504 aa)
ENSMNEP0000000920414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (224 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
ENSMNEP00000011545Uncharacterized protein. (81 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
RB1RB transcriptional corepressor 1. (928 aa)
ENSMNEP00000012002TNF receptor-associated factor. (457 aa)
NFATC4Nuclear factor of activated T cells 4. (961 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
TMED7Transmembrane p24 trafficking protein 7. (224 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (463 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (422 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
EP300E1A binding protein p300. (2397 aa)
MAPK10Mitogen-activated protein kinase. (489 aa)
TBK1TANK binding kinase 1. (729 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CREBBPCREB binding protein. (2442 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LOC105498430Uncharacterized protein. (189 aa)
E2F3E2F transcription factor 3. (465 aa)
ENSMNEP00000041867Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa)
HSPG2Heparan sulfate proteoglycan 2. (4392 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
BADBCL2 associated agonist of cell death. (167 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
ENSMNEP00000045253Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (234 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CSDE1Cold shock domain containing E1. (844 aa)
BIRC5Uncharacterized protein. (147 aa)
PPP1R14BUncharacterized protein. (208 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
IL6Interleukin 6. (214 aa)
LOC105487609Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ERASES cell expressed Ras. (233 aa)
IFNA6Interferon alpha 6. (190 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
LOC105491771Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105497820Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
TLR2Toll-like receptor. (784 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
MAVSMitochondrial antiviral signaling protein. (541 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
LOC105495842Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMNEP00000002161Uncharacterized protein. (142 aa)
ENSMNEP00000002263Uncharacterized protein. (329 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
NFATC1Nuclear factor of activated T cells 1. (988 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
LOC105486922Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMNEP00000004019Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
LOC105477037Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
LOC105495023Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (717 aa)
TICAM2Toll like receptor adaptor molecule 2. (235 aa)
LOC105477715Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
LOC105492342Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
EGR2Early growth response 2. (426 aa)
DDX58DExD/H-box helicase 58. (925 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
IFNA14Interferon alpha 14. (137 aa)
ENSMNEP0000003668614_3_3 domain-containing protein; Belongs to the 14-3-3 family. (234 aa)
MAPK9Mitogen-activated protein kinase 9. (354 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (257 aa)
E2F2E2F transcription factor 2. (439 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
C7orf31Chromosome 7 open reading frame 31. (590 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
JAK3Tyrosine-protein kinase. (1088 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (472 aa)
FASLGTumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
VDAC3Voltage dependent anion channel 3. (284 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (487 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (446 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1345 aa)
ENSMNEP0000003171314_3_3 domain-containing protein. (92 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (270 aa)
TYK2Tyrosine-protein kinase. (1190 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
SLC10A1Solute carrier family 10 member 1. (349 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
TICAM1Toll like receptor adaptor molecule 1. (519 aa)
ENSMNEP0000002930514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (214 aa)
LOC105498418Uncharacterized protein. (190 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
IFNB1Interferon beta 1. (187 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
ATF4Activating transcription factor 4. (351 aa)
IRF3Interferon regulatory factor 3. (422 aa)
ENSMNEP00000027902Protein kinase domain-containing protein. (365 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (520 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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