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| | LOC105480535 | TIR domain-containing protein. (1033 aa) |
| | PPP1R14B | Uncharacterized protein. (208 aa) |
| | ENSMNEP00000010486 | Ig-like domain-containing protein. (133 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (968 aa) |
| | LOC105498547 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (551 aa) |
| | ENSMNEP00000011545 | Uncharacterized protein. (81 aa) |
| | ENSMNEP00000012002 | TNF receptor-associated factor. (457 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa) |
| | RAB9A | RAB9A, member RAS oncogene family. (201 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa) |
| | HSPA1L | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | IL6 | Interleukin 6. (214 aa) |
| | LOC105487609 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | STAT1 | Signal transducer and activator of transcription. (758 aa) |
| | LOC105491771 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC105497820 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | TLR2 | Toll-like receptor. (784 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (541 aa) |
| | LOC105495842 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | BBC3 | BCL2 binding component 3. (261 aa) |
| | ENSMNEP00000002263 | Uncharacterized protein. (329 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | LOC105486922 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TRADD | TNFRSF1A associated via death domain. (308 aa) |
| | ENSMNEP00000004019 | Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa) |
| | LOC105477037 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC105495023 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (717 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa) |
| | LOC105477715 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | LOC105492342 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | CD46 | CD46 molecule. (399 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (407 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (345 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa) |
| | PIK3R2 | Uncharacterized protein. (668 aa) |
| | IRF7 | Interferon regulatory factor 7. (504 aa) |
| | RCHY1 | Ring finger and CHY zinc finger domain containing 1. (261 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa) |
| | IL2RA | Interleukin 2 receptor subunit alpha. (272 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (590 aa) |
| | MSN | Moesin. (577 aa) |
| | MAPK9 | Mitogen-activated protein kinase 9. (354 aa) |
| | IFNAR2 | Uncharacterized protein. (516 aa) |
| | IFNA14 | Interferon alpha 14. (137 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | DDX58 | DExD/H-box helicase 58. (925 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (463 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | IL2RB | Interleukin 2 receptor subunit beta. (551 aa) |
| | ENSMNEP00000040265 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (586 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (489 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | LOC105498430 | Uncharacterized protein. (189 aa) |
| | JAK3 | Tyrosine-protein kinase. (1088 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (224 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (488 aa) |
| | TRAV22 | T cell receptor alpha variable 22. (147 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (487 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) |
| | HSPA8 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa) |
| | ENSMNEP00000031290 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (579 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | CD3G | CD3g molecule. (209 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (270 aa) |
| | TYK2 | Tyrosine-protein kinase. (1190 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | TRAC | T cell receptor alpha constant. (110 aa) |
| | ENSMNEP00000030339 | Uncharacterized protein. (459 aa) |
| | MX2 | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (715 aa) |
| | LOC105498418 | Uncharacterized protein. (190 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (242 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ENSMNEP00000028604 | IGv domain-containing protein. (139 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | IRF3 | Interferon regulatory factor 3. (422 aa) |
| | TLR7 | Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa) |
| | LIMCH1 | LIM and calponin homology domains 1. (1626 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule family member 1. (356 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (790 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa) |
| | ENSMNEP00000023823 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (520 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | CBLB | Cbl proto-oncogene B. (961 aa) |
| | ENSMNEP00000023427 | Uncharacterized protein. (198 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (203 aa) |
| | ENSMNEP00000021373 | Uncharacterized protein. (72 aa) |
| | HSPA2 | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa) |
| | STAT2 | Signal transducer and activator of transcription. (852 aa) |
| | HSPA6 | Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (537 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | ENSMNEP00000019824 | Uncharacterized protein. (194 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | CD28 | CD28 molecule. (220 aa) |
| | EIF3H | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (366 aa) |
| | ENSMNEP00000019155 | Interfer-bind domain-containing protein. (338 aa) |
| | CD3D | CD3d molecule. (171 aa) |
| | STAT3 | Signal transducer and activator of transcription. (660 aa) |
| | CD3E | CD3e molecule. (198 aa) |
| | RACK1 | Receptor for activated C kinase 1. (317 aa) |
| | CD209 | CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity). (413 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2 alpha kinase 1. (605 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa) |
| | MX1 | MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (661 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (1025 aa) |
| | STAT5B | Signal transducer and activator of transcription. (783 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (421 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (293 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (260 aa) |
| | BID | BH3 interacting domain death agonist. (266 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | IRF9 | Interferon regulatory factor 9. (392 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | ADAR | Adenosine deaminase RNA specific. (1364 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (369 aa) |
| | CSNK2B | Uncharacterized protein. (298 aa) |
| | ENSMNEP00000013313 | Uncharacterized protein. (152 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (687 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | ENSMNEP00000041867 | Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (488 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1076 aa) |
| | NFKBIB | NFKB inhibitor beta. (356 aa) |
