STRINGSTRING
ENSMNEP00000007368 ENSMNEP00000007368 GNA11 GNA11 CCR3 CCR3 CSDE1 CSDE1 MAPK14 MAPK14 ADCY3 ADCY3 KRAS KRAS RPS6KB1 RPS6KB1 ADCY2 ADCY2 GNAO1 GNAO1 CDKN2A CDKN2A CGAS CGAS NRAS NRAS PLCB1 PLCB1 IL6R IL6R GNG4 GNG4 TSC2 TSC2 GNG12 GNG12 ENSMNEP00000043350 ENSMNEP00000043350 ROCK2 ROCK2 CREB3 CREB3 MAP2K2 MAP2K2 SOS1 SOS1 CALM1 CALM1 GNGT1 GNGT1 ENSMNEP00000041867 ENSMNEP00000041867 ADCY5 ADCY5 PPP3R1 PPP3R1 E2F3 E2F3 LOC105498430 LOC105498430 ADCY6 ADCY6 PRKACA PRKACA TBK1 TBK1 ENSMNEP00000040169 ENSMNEP00000040169 PPP3CC PPP3CC CREB3L4 CREB3L4 MAPK12 MAPK12 AKT3 AKT3 ARHGEF11 ARHGEF11 GNG14 GNG14 PIK3R3 PIK3R3 RHEB RHEB RHOA RHOA GNG13 GNG13 ADCY4 ADCY4 ENSMNEP00000037129 ENSMNEP00000037129 TAP1 TAP1 IFNA14 IFNA14 TAP2 TAP2 MDM2 MDM2 E2F2 E2F2 CREB3L1 CREB3L1 SP1 SP1 ENSMNEP00000036315 ENSMNEP00000036315 VEGFA VEGFA GNG3 GNG3 C7orf31 C7orf31 CYCS CYCS ENSMNEP00000035333 ENSMNEP00000035333 GNB5 GNB5 CCND1 CCND1 CDK6 CDK6 MAPK13 MAPK13 CREB3L2 CREB3L2 RAF1 RAF1 ENSMNEP00000034688 ENSMNEP00000034688 FASLG FASLG LOC105485102 LOC105485102 ADCY8 ADCY8 IKBKB IKBKB GNA13 GNA13 IL1B IL1B GNA12 GNA12 ENSMNEP00000033181 ENSMNEP00000033181 CASP8 CASP8 CREB3L3 CREB3L3 NFKBIA NFKBIA CRK CRK HLA-F HLA-F STING1 STING1 HRAS HRAS PRKACB PRKACB TRAF5 TRAF5 RAC1 RAC1 PIK3CD PIK3CD CCL2 CCL2 TP53 TP53 PIK3R1 PIK3R1 GNAI1 GNAI1 PXN PXN CALM3 CALM3 ENSMNEP00000029248 ENSMNEP00000029248 LOC105498418 LOC105498418 TNF TNF ATF2 ATF2 FADD FADD IFNB1 IFNB1 ENSMNEP00000028956 ENSMNEP00000028956 AKT2 AKT2 ROCK1 ROCK1 PRKCG PRKCG PRKCA PRKCA RELA RELA ATF4 ATF4 GNG5 GNG5 IRF3 IRF3 PTGER2 PTGER2 ENSMNEP00000027902 ENSMNEP00000027902 TSC1 TSC1 PPP3CA PPP3CA GRB2 GRB2 CALM2 CALM2 RHOC RHOC LPXN LPXN MAP2K6 MAP2K6 ITPR3 ITPR3 GNB3 GNB3 MANE-E MANE-E AKT1 AKT1 GNB1 GNB1 AKAP13 AKAP13 RUFY4 RUFY4 BCAR1 BCAR1 PTK2 PTK2 GNAI3 GNAI3 CALML6 CALML6 PVALEF PVALEF ITPR1 ITPR1 ENSMNEP00000023924 ENSMNEP00000023924 ENSMNEP00000023427 ENSMNEP00000023427 BAX BAX LOC105469851 LOC105469851 PTRHD1 PTRHD1 IL10RA IL10RA PDGFRA PDGFRA CXCL8 CXCL8 CALR CALR NFATC2 NFATC2 CCL5 CCL5 GNAS GNAS LOC105485104 LOC105485104 CREB5 CREB5 GNAI2 GNAI2 PIK3CA PIK3CA ARHGEF12 ARHGEF12 CRKL CRKL PTGS2 PTGS2 RAC2 RAC2 STAT3 STAT3 CX3CL1 CX3CL1 ENSMNEP00000018745 ENSMNEP00000018745 CALML4 CALML4 PTK2B PTK2B PPP3CB PPP3CB CXCR4 CXCR4 CASP9 CASP9 ELK1 ELK1 EIF4EBP1 EIF4EBP1 RPS6KB2 RPS6KB2 ENSMNEP00000016414 ENSMNEP00000016414 RHEBL1 RHEBL1 CDK4 CDK4 BID BID MAPK3 MAPK3 GNG11 GNG11 ENSMNEP00000013537 ENSMNEP00000013537 PTGER4 PTGER4 ENSMNEP00000013313 ENSMNEP00000013313 ENSMNEP00000013158 ENSMNEP00000013158 ENSMNEP00000013138 ENSMNEP00000013138 LOC105468574 LOC105468574 CHUK CHUK CCR5 CCR5 IL10RB IL10RB NFATC4 NFATC4 RB1 RB1 CREB1 CREB1 MAPK11 MAPK11 MAPK1 MAPK1 TNFRSF1A TNFRSF1A GNGT2 GNGT2 NFKB1 NFKB1 BAK1 BAK1 RIPK1 RIPK1 GNG2 GNG2 GNG10 GNG10 IL1R1 IL1R1 MTOR MTOR GNG8 GNG8 GNAQ GNAQ PTGER1 PTGER1 TAPBP TAPBP CXCL12 CXCL12 GNB2 GNB2 PLCB4 PLCB4 ATF6B ATF6B ITGB3 ITGB3 ADCY1 ADCY1 ARHGEF1 ARHGEF1 GNB4 GNB4 ADCY7 ADCY7 RAC3 RAC3 PIK3R2 PIK3R2 PLCB2 PLCB2 GNG7 GNG7 PLCB3 PLCB3 LOC105466472 LOC105466472 FAS FAS SOS2 SOS2 MAP2K1 MAP2K1 SRC SRC E2F1 E2F1 GSK3B GSK3B PRKCB PRKCB LOC105492342 LOC105492342 ENSMNEP00000005419 ENSMNEP00000005419 NFATC3 NFATC3 EGFR EGFR LOC105477715 LOC105477715 ENSMNEP00000005141 ENSMNEP00000005141 ITPR2 ITPR2 LOC105495023 LOC105495023 MYC MYC TRAF2 TRAF2 LOC105477037 LOC105477037 ENSMNEP00000004019 ENSMNEP00000004019 TRADD TRADD ADCY9 ADCY9 LOC105486922 LOC105486922 NFATC1 NFATC1 PDIA3 PDIA3 ITGAV ITGAV ENSMNEP00000002738 ENSMNEP00000002738 LOC105495842 LOC105495842 CDKN1A CDKN1A JAK1 JAK1 CALML3 CALML3 B2M B2M HLA-G HLA-G LOC105497820 LOC105497820 LOC105491771 LOC105491771 PTGER3 PTGER3 CTNNB1 CTNNB1 IFNA6 IFNA6 ERAS ERAS LOC105487609 LOC105487609 IL6 IL6 LOC105470579 LOC105470579 LOC105467297 LOC105467297 PIK3CB PIK3CB IKBKG IKBKG MANE-B MANE-B
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000007368MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (168 aa)
GNA11G protein subunit alpha 11. (346 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa)
CSDE1Cold shock domain containing E1. (844 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
GNAO1G protein subunit alpha o1. (354 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (160 aa)
CGASCyclic GMP-AMP synthase. (522 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
IL6RInterleukin 6 receptor. (467 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
TSC2TSC complex subunit 2. (1807 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSMNEP00000043350Ig-like domain-containing protein. (233 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa)
CALM1Calmodulin 1. (149 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSMNEP00000041867Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
PPP3R1Uncharacterized protein. (189 aa)
E2F3E2F transcription factor 3. (465 aa)
LOC105498430Uncharacterized protein. (189 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1214 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
TBK1TANK binding kinase 1. (729 aa)
ENSMNEP00000040169Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (422 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1562 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (463 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
RHOARas homolog family member A. (193 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
ADCY4Adenylate cyclase 4. (1299 aa)
ENSMNEP00000037129Ig-like domain-containing protein. (346 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (808 aa)
IFNA14Interferon alpha 14. (137 aa)
TAP2Transporter 2, ATP binding cassette subfamily B member. (711 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa)
E2F2E2F transcription factor 2. (439 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
SP1Sp1 transcription factor. (786 aa)
ENSMNEP00000036315Uncharacterized protein. (182 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (452 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
C7orf31Chromosome 7 open reading frame 31. (590 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMNEP00000035333Ig-like domain-containing protein; Belongs to the MHC class I family. (356 aa)
GNB5G protein subunit beta 5. (409 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
ENSMNEP00000034688Uncharacterized protein. (288 aa)
FASLGTumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa)
LOC105485102C-C motif chemokine. (92 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
GNA13G protein subunit alpha 13. (377 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
GNA12G protein subunit alpha 12. (314 aa)
ENSMNEP00000033181Ig-like domain-containing protein; Belongs to the MHC class I family. (393 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (487 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (446 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
HLA-FMajor histocompatibility complex, class I, F; Belongs to the MHC class I family. (440 aa)
STING1Transmembrane protein 173. (379 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
RAC1Rac family small GTPase 1. (211 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
CCL2C-C motif chemokine. (99 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (270 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
GNAI1G protein subunit alpha i1. (422 aa)
PXNPaxillin. (1082 aa)
CALM3Calmodulin 3. (149 aa)
ENSMNEP00000029248MHC_I-like_Ag-recog domain-containing protein. (172 aa)
LOC105498418Uncharacterized protein. (190 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
IFNB1Interferon beta 1. (187 aa)
ENSMNEP00000028956Uncharacterized protein. (185 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
ATF4Activating transcription factor 4. (351 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
IRF3Interferon regulatory factor 3. (422 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
ENSMNEP00000027902Protein kinase domain-containing protein. (365 aa)
TSC1TSC complex subunit 1. (1138 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CALM2Calmodulin 1; Belongs to the calmodulin family. (149 aa)
RHOCRas homolog family member C. (193 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
GNB3G protein subunit beta 3. (340 aa)
MANE-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GNB1G protein subunit beta 1. (340 aa)
AKAP13A-kinase anchoring protein 13. (2830 aa)
RUFY4RUN and FYVE domain containing 4. (571 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa)
GNAI3G protein subunit alpha i3. (328 aa)
CALML6Calmodulin like 6. (181 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
ENSMNEP00000023924MHC_I-like_Ag-recog domain-containing protein. (162 aa)
ENSMNEP00000023427Uncharacterized protein. (198 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
LOC105469851Ig-like domain-containing protein; Belongs to the MHC class I family. (381 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
IL10RAInterleukin 10 receptor subunit alpha. (580 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
CXCL8Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
CALRCalreticulin. (417 aa)
NFATC2Nuclear factor of activated T cells 2. (921 aa)
CCL5C-C motif chemokine. (91 aa)
GNASGNAS complex locus. (1007 aa)
LOC105485104C-C motif chemokine. (92 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1484 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
RAC2Rac family small GTPase 2. (192 aa)
STAT3Signal transducer and activator of transcription. (660 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (407 aa)
ENSMNEP00000018745Ig-like domain-containing protein; Belongs to the MHC class I family. (317 aa)
CALML4Calmodulin like 4. (193 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (409 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (421 aa)
ELK1ETS transcription factor ELK1. (428 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
ENSMNEP00000016414Uncharacterized protein; Belongs to the calmodulin family. (179 aa)
RHEBL1RHEB like 1. (183 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (260 aa)
BIDBH3 interacting domain death agonist. (266 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSMNEP00000013537C-C motif chemokine. (103 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
ENSMNEP00000013313Uncharacterized protein. (152 aa)
ENSMNEP00000013158Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
ENSMNEP00000013138Ig-like domain-containing protein; Belongs to the MHC class I family. (352 aa)
LOC105468574C-C motif chemokine. (92 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
CCR5C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (379 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
NFATC4Nuclear factor of activated T cells 4. (961 aa)
RB1RB transcriptional corepressor 1. (928 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (693 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNAQG protein subunit alpha q. (359 aa)
PTGER1Prostaglandin E receptor 1. (402 aa)
TAPBPTAP binding protein. (504 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
GNB2G protein subunit beta 2. (340 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ATF6BActivating transcription factor 6 beta. (710 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1088 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (972 aa)
GNB4G protein subunit beta 4. (340 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
RAC3Rac family small GTPase 3. (192 aa)
PIK3R2Uncharacterized protein. (668 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1174 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
LOC105466472Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa)
FASTumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (361 aa)
SRCTyrosine-protein kinase. (644 aa)
E2F1E2F transcription factor 1. (437 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC105492342Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
ENSMNEP00000005419Uncharacterized protein. (114 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
LOC105477715Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
ENSMNEP00000005141Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
LOC105495023Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (532 aa)
LOC105477037Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMNEP00000004019Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
LOC105486922Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
NFATC1Nuclear factor of activated T cells 1. (988 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1017 aa)
ENSMNEP00000002738Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC105495842Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
HLA-GIGc1 domain-containing protein; Belongs to the MHC class I family. (354 aa)
LOC105497820Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105491771Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
PTGER3Prostaglandin E receptor 3. (404 aa)
CTNNB1Catenin beta 1. (781 aa)
IFNA6Interferon alpha 6. (190 aa)
ERASES cell expressed Ras. (233 aa)
LOC105487609Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
IL6Interleukin 6. (214 aa)
LOC105470579Uncharacterized protein. (245 aa)
LOC105467297Ig-like domain-containing protein; Belongs to the MHC class I family. (242 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa)
MANE-BIg-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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