Your Input: | |
| | ENSMNEP00000045959 | Uncharacterized protein. (66 aa) |
| | MANE-B | Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | LOC105467297 | Ig-like domain-containing protein; Belongs to the MHC class I family. (242 aa) |
| | CCNB1 | Cyclin B1; Belongs to the cyclin family. (433 aa) |
| | LOC105487609 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3032 aa) |
| | LOC105491771 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC105497820 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | HLA-G | IGc1 domain-containing protein; Belongs to the MHC class I family. (354 aa) |
| | TLR2 | Toll-like receptor. (784 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | TRIM22 | Tripartite motif containing 22. (498 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | LOC105495842 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSMNEP00000002738 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (988 aa) |
| | AP1M1 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (435 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | LOC105486922 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TRADD | TNFRSF1A associated via death domain. (308 aa) |
| | ENSMNEP00000004019 | Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa) |
| | LOC105477037 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (501 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (532 aa) |
| | LOC105495023 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (717 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | ENSMNEP00000005141 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | LOC105477715 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1075 aa) |
| | LOC105492342 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1. (361 aa) |
| | PAK5 | Non-specific serine/threonine protein kinase. (719 aa) |
| | RNF7 | Ring finger protein 7. (113 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa) |
| | ENSMNEP00000007368 | MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (168 aa) |
| | LOC105466472 | Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | AP1S2 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa) |
| | PIK3R2 | Uncharacterized protein. (668 aa) |
| | RAC3 | Rac family small GTPase 3. (192 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | PLVAP | Plasmalemma vesicle associated protein. (442 aa) |
| | TAPBP | TAP binding protein. (504 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa) |
| | GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | ENSMNEP00000010486 | Ig-like domain-containing protein. (133 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (693 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (968 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (484 aa) |
| | ENSMNEP00000011545 | Uncharacterized protein. (81 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | ENSMNEP00000012002 | TNF receptor-associated factor. (457 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (961 aa) |
| | CCR5 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (379 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | ENSMNEP00000013138 | Ig-like domain-containing protein; Belongs to the MHC class I family. (352 aa) |
| | ENSMNEP00000013158 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa) |
| | ENSMNEP00000013313 | Uncharacterized protein. (152 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1147 aa) |
| | CUL5 | Cullin 5; Belongs to the cullin family. (780 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | BID | BH3 interacting domain death agonist. (266 aa) |
| | ENSMNEP00000016414 | Uncharacterized protein; Belongs to the calmodulin family. (179 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa) |
| | ENSMNEP00000016854 | ADF-H domain-containing protein. (135 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (421 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | AP1G2 | AP-1 complex subunit gamma. (785 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (409 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (702 aa) |
| | ENSMNEP00000017370 | Uncharacterized protein; Belongs to the cyclin family. (341 aa) |
| | WEE2 | Wee1-like protein kinase. (568 aa) |
| | AP1B1 | AP complex subunit beta. (949 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | ELOC | Elongin C; Belongs to the SKP1 family. (112 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa) |
| | CALML4 | Calmodulin like 4. (193 aa) |
| | CD3E | CD3e molecule. (198 aa) |
| | ENSMNEP00000018745 | Ig-like domain-containing protein; Belongs to the MHC class I family. (317 aa) |
| | CD3D | CD3d molecule. (171 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (563 aa) |
| | ENSMNEP00000019824 | Uncharacterized protein. (194 aa) |
| | CFL1 | ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (196 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CCDC125 | Coiled-coil domain containing 125. (510 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | AP1S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa) |
| | ENSMNEP00000021101 | Zf-rbx1 domain-containing protein. (93 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (921 aa) |
| | CALR | Calreticulin. (417 aa) |
| | AP1G1 | AP-1 complex subunit gamma. (825 aa) |
| | CCNB3 | Cyclin B3; Belongs to the cyclin family. (1363 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | LOC105469851 | Ig-like domain-containing protein; Belongs to the MHC class I family. (381 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (203 aa) |
| | ENSMNEP00000023427 | Uncharacterized protein. (198 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | CNTD2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (304 aa) |
| | CUL4B | Cullin 4B; Belongs to the cullin family. (913 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (384 aa) |
| | ELOB | Elongin B. (167 aa) |
| | ENSMNEP00000023924 | MHC_I-like_Ag-recog domain-containing protein. (162 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa) |
| | PVALEF | Parvalbumin like EF-hand containing. (133 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | GNAI3 | G protein subunit alpha i3. (328 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (462 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa) |
| | CDC25C | Cell division cycle 25C. (507 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | BST2 | Bone marrow stromal cell antigen 2. (182 aa) |
| | LIMK2 | LIM domain kinase 2. (638 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | MANE-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa) |
| | CALM2 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | ENSMNEP00000027902 | Protein kinase domain-containing protein. (365 aa) |
| | IRF3 | Interferon regulatory factor 3. (422 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | ENSMNEP00000028604 | IGv domain-containing protein. (139 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ENSMNEP00000028956 | Uncharacterized protein. (185 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC105498418 | Uncharacterized protein. (190 aa) |
| | ENSMNEP00000029248 | MHC_I-like_Ag-recog domain-containing protein. (172 aa) |
| | RBX1 | RING-type domain-containing protein. (108 aa) |
| | CALM3 | Calmodulin 3. (149 aa) |
| | PXN | Paxillin. (1082 aa) |
| | TRAC | T cell receptor alpha constant. (110 aa) |
| | CCNB2 | Cyclin B2; Belongs to the cyclin family. (391 aa) |
| | TRIM6 | Tripartite motif containing 6. (559 aa) |
| | GNAI1 | G protein subunit alpha i1. (422 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | LOC105468609 | Uncharacterized protein. (488 aa) |
| | APOBEC3G | Apolipoprotein B mRNA editing enzyme catalytic subunit 3G. (431 aa) |
| | CD3G | CD3g molecule. (209 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | RAC1 | Rac family small GTPase 1. (211 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa) |
| | CFL2 | Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa) |
| | APOBEC3H | Apolipoprotein B mRNA editing enzyme catalytic subunit 3H. (211 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | STING1 | Transmembrane protein 173. (379 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | HLA-F | Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (440 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (487 aa) |
| | PAK3 | P21 (RAC1) activated kinase 3. (580 aa) |
| | ENSMNEP00000033181 | Ig-like domain-containing protein; Belongs to the MHC class I family. (393 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | TRAV22 | T cell receptor alpha variable 22. (147 aa) |
| | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (597 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) |
| | ENSMNEP00000034688 | Uncharacterized protein. (288 aa) |
| | ENSMNEP00000034709 | Uncharacterized protein. (439 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa) |
| | GNB5 | G protein subunit beta 5. (409 aa) |
| | ENSMNEP00000035333 | Ig-like domain-containing protein; Belongs to the MHC class I family. (356 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (590 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | ENSMNEP00000036315 | Uncharacterized protein. (182 aa) |
| | CD247 | CD247 molecule. (164 aa) |
| | LIMK1 | LIM domain kinase 1. (677 aa) |
| | MAPK9 | Mitogen-activated protein kinase 9. (354 aa) |
| | TAP2 | Transporter 2, ATP binding cassette subfamily B member. (711 aa) |
| | IFNA14 | Interferon alpha 14. (137 aa) |
| | TAP1 | Transporter 1, ATP binding cassette subfamily B member. (808 aa) |
| | ENSMNEP00000037129 | Ig-like domain-containing protein. (346 aa) |
| | ENSMNEP00000037456 | RING-type domain-containing protein. (100 aa) |
| | AP1S3 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (164 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | GNG13 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa) |
| | AP1M2 | AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (400 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (463 aa) |
| | GNG14 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1478 aa) |
| | ENSMNEP00000039400 | Ubiquitin-like domain-containing protein. (104 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | CCDC194 | Coiled-coil domain containing 194. (234 aa) |
| | PPP1R14B | Uncharacterized protein. (208 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (520 aa) |
| | ENSMNEP00000040169 | Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa) |
| | CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa) |
| | ENSMNEP00000040658 | Uncharacterized protein. (348 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (489 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | APOBEC3D | Uncharacterized protein. (395 aa) |
| | ENSMNEP00000041202 | ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (209 aa) |
| | LOC105498430 | Uncharacterized protein. (189 aa) |
| | PPP3R1 | Uncharacterized protein. (189 aa) |
| | ENSMNEP00000041867 | Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (745 aa) |
| | ENSMNEP00000042218 | Uncharacterized protein; Belongs to the SKP1 family. (171 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | CALM1 | Calmodulin 1. (149 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | ENSMNEP00000043350 | Ig-like domain-containing protein. (233 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (545 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (522 aa) |
| | CHEK1 | Checkpoint kinase 1. (493 aa) |
| | GNAO1 | G protein subunit alpha o1. (354 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (681 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | APOBEC3C | Apolipoprotein B mRNA editing enzyme catalytic subunit 3C. (190 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | GNA11 | G protein subunit alpha 11. (346 aa) |
