STRINGSTRING
ENSMNEP00000012002 ENSMNEP00000012002 GNA11 GNA11 CSDE1 CSDE1 MAPK14 MAPK14 APOBEC3C APOBEC3C KRAS KRAS RPS6KB1 RPS6KB1 PAK6 PAK6 GNAO1 GNAO1 CHEK1 CHEK1 CGAS CGAS PAK1 PAK1 NRAS NRAS BAD BAD GNG4 GNG4 GNG12 GNG12 ENSMNEP00000043350 ENSMNEP00000043350 MAP2K2 MAP2K2 CALM1 CALM1 CDK1 CDK1 BTRC BTRC GNGT1 GNGT1 ENSMNEP00000042218 ENSMNEP00000042218 CUL4A CUL4A ENSMNEP00000041867 ENSMNEP00000041867 PPP3R1 PPP3R1 LOC105498430 LOC105498430 ENSMNEP00000041202 ENSMNEP00000041202 APOBEC3D APOBEC3D TBK1 TBK1 MAPK10 MAPK10 ENSMNEP00000040658 ENSMNEP00000040658 CD4 CD4 ENSMNEP00000040169 ENSMNEP00000040169 PPP3CC PPP3CC CCDC194 CCDC194 PLCG1 PLCG1 MAPK12 MAPK12 ENSMNEP00000039400 ENSMNEP00000039400 DCAF1 DCAF1 AKT3 AKT3 TAB1 TAB1 GNG14 GNG14 PIK3R3 PIK3R3 AP1M2 AP1M2 GNG13 GNG13 TRAF6 TRAF6 AP1S3 AP1S3 ENSMNEP00000037456 ENSMNEP00000037456 ENSMNEP00000037129 ENSMNEP00000037129 TAP1 TAP1 IFNA14 IFNA14 TAP2 TAP2 MAPK9 MAPK9 LIMK1 LIMK1 CD247 CD247 ENSMNEP00000036315 ENSMNEP00000036315 GNG3 GNG3 C7orf31 C7orf31 CYCS CYCS WEE1 WEE1 ENSMNEP00000035333 ENSMNEP00000035333 GNB5 GNB5 TLR4 TLR4 MAPK13 MAPK13 RAF1 RAF1 ENSMNEP00000034709 ENSMNEP00000034709 ENSMNEP00000034688 ENSMNEP00000034688 FASLG FASLG SAMHD1 SAMHD1 TRAV22 TRAV22 IKBKB IKBKB IRAK4 IRAK4 ENSMNEP00000033181 ENSMNEP00000033181 PAK3 PAK3 CASP8 CASP8 NFKBIA NFKBIA CRK CRK HLA-F HLA-F MAP3K7 MAP3K7 MYD88 MYD88 STING1 STING1 HRAS HRAS APOBEC3H APOBEC3H CFL2 CFL2 TRAF5 TRAF5 RAC1 RAC1 PIK3CD PIK3CD CD3G CD3G APOBEC3G APOBEC3G LOC105468609 LOC105468609 PIK3R1 PIK3R1 GNAI1 GNAI1 TRIM6 TRIM6 CCNB2 CCNB2 TRAC TRAC PXN PXN CALM3 CALM3 RBX1 RBX1 ENSMNEP00000029248 ENSMNEP00000029248 LOC105498418 LOC105498418 TNF TNF FADD FADD IFNB1 IFNB1 ENSMNEP00000028956 ENSMNEP00000028956 AKT2 AKT2 PRKCG PRKCG PRKCA PRKCA ENSMNEP00000028604 ENSMNEP00000028604 RELA RELA GNG5 GNG5 IRF3 IRF3 ENSMNEP00000027902 ENSMNEP00000027902 PPP3CA PPP3CA CALM2 CALM2 LPXN LPXN MAP2K6 MAP2K6 ITPR3 ITPR3 GNB3 GNB3 MANE-E MANE-E AKT1 AKT1 LIMK2 LIMK2 BST2 BST2 GNB1 GNB1 CDC25C CDC25C PTK2 PTK2 TNFRSF1B TNFRSF1B GNAI3 GNAI3 CALML6 CALML6 PVALEF PVALEF ITPR1 ITPR1 ENSMNEP00000023924 ENSMNEP00000023924 ELOB ELOB MAP2K7 MAP2K7 CUL4B CUL4B CNTD2 CNTD2 BCL2 BCL2 ENSMNEP00000023427 ENSMNEP00000023427 BAX BAX LOC105469851 LOC105469851 CUL1 CUL1 CCNB3 CCNB3 AP1G1 AP1G1 CALR CALR NFATC2 NFATC2 ENSMNEP00000021101 ENSMNEP00000021101 AP1S1 AP1S1 GNAI2 GNAI2 CCDC125 CCDC125 PIK3CA PIK3CA CFL1 CFL1 ENSMNEP00000019824 ENSMNEP00000019824 FBXW11 FBXW11 CRKL CRKL RAC2 RAC2 CD3D CD3D ENSMNEP00000018745 ENSMNEP00000018745 CD3E CD3E CALML4 CALML4 PTK2B PTK2B ELOC ELOC MAP2K3 MAP2K3 PPP3CB PPP3CB AP1B1 AP1B1 WEE2 WEE2 ENSMNEP00000017370 ENSMNEP00000017370 PAK4 PAK4 CXCR4 CXCR4 AP1G2 AP1G2 SKP1 SKP1 CASP9 CASP9 ENSMNEP00000016854 ENSMNEP00000016854 RPS6KB2 RPS6KB2 ENSMNEP00000016414 ENSMNEP00000016414 BID BID MAPK3 MAPK3 GNG11 GNG11 CUL5 CUL5 DDB1 DDB1 FOS FOS ENSMNEP00000013313 ENSMNEP00000013313 ENSMNEP00000013158 ENSMNEP00000013158 ENSMNEP00000013138 ENSMNEP00000013138 MAPK8 MAPK8 CHUK CHUK CCR5 CCR5 NFATC4 NFATC4 MAPK11 MAPK11 MAPK1 MAPK1 TNFRSF1A TNFRSF1A ENSMNEP00000011545 ENSMNEP00000011545 TRIM5 TRIM5 GNGT2 GNGT2 NFKB1 NFKB1 BAK1 BAK1 RIPK1 RIPK1 GNG2 GNG2 ENSMNEP00000010486 ENSMNEP00000010486 GNG10 GNG10 MTOR MTOR GNG8 GNG8 GNAQ GNAQ TAPBP TAPBP PLVAP PLVAP GNB2 GNB2 GNB4 GNB4 RAC3 RAC3 PIK3R2 PIK3R2 AP1S2 AP1S2 GNG7 GNG7 LOC105466472 LOC105466472 ENSMNEP00000007368 ENSMNEP00000007368 FAS FAS RNF7 RNF7 PAK5 PAK5 MAP2K1 MAP2K1 PRKCB PRKCB LOC105492342 LOC105492342 NFATC3 NFATC3 LOC105477715 LOC105477715 ENSMNEP00000005141 ENSMNEP00000005141 ITPR2 ITPR2 IRAK1 IRAK1 LOC105495023 LOC105495023 TRAF2 TRAF2 PAK2 PAK2 LOC105477037 LOC105477037 ENSMNEP00000004019 ENSMNEP00000004019 TRADD TRADD LOC105486922 LOC105486922 TAB2 TAB2 AP1M1 AP1M1 NFATC1 NFATC1 PLCG2 PLCG2 PDIA3 PDIA3 BCL2L1 BCL2L1 ENSMNEP00000002738 ENSMNEP00000002738 LOC105495842 LOC105495842 CALML3 CALML3 B2M B2M TRIM22 TRIM22 ATR ATR TLR2 TLR2 HLA-G HLA-G LOC105497820 LOC105497820 LOC105491771 LOC105491771 ATM ATM IFNA6 IFNA6 ERAS ERAS LOC105487609 LOC105487609 CCNB1 CCNB1 LOC105467297 LOC105467297 PIK3CB PIK3CB IKBKG IKBKG MANE-B MANE-B PPP1R14B PPP1R14B ENSMNEP00000045959 ENSMNEP00000045959
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000012002TNF receptor-associated factor. (457 aa)
GNA11G protein subunit alpha 11. (346 aa)
CSDE1Cold shock domain containing E1. (844 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
APOBEC3CApolipoprotein B mRNA editing enzyme catalytic subunit 3C. (190 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
GNAO1G protein subunit alpha o1. (354 aa)
CHEK1Checkpoint kinase 1. (493 aa)
CGASCyclic GMP-AMP synthase. (522 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
BADBCL2 associated agonist of cell death. (167 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSMNEP00000043350Ig-like domain-containing protein. (233 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
CALM1Calmodulin 1. (149 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSMNEP00000042218Uncharacterized protein; Belongs to the SKP1 family. (171 aa)
CUL4ACullin 4A; Belongs to the cullin family. (745 aa)
ENSMNEP00000041867Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa)
PPP3R1Uncharacterized protein. (189 aa)
LOC105498430Uncharacterized protein. (189 aa)
ENSMNEP00000041202ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (209 aa)
APOBEC3DUncharacterized protein. (395 aa)
TBK1TANK binding kinase 1. (729 aa)
MAPK10Mitogen-activated protein kinase. (489 aa)
ENSMNEP00000040658Uncharacterized protein. (348 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
ENSMNEP00000040169Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
CCDC194Coiled-coil domain containing 194. (234 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
ENSMNEP00000039400Ubiquitin-like domain-containing protein. (104 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1478 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (463 aa)
AP1M2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (400 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (164 aa)
ENSMNEP00000037456RING-type domain-containing protein. (100 aa)
ENSMNEP00000037129Ig-like domain-containing protein. (346 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (808 aa)
IFNA14Interferon alpha 14. (137 aa)
TAP2Transporter 2, ATP binding cassette subfamily B member. (711 aa)
MAPK9Mitogen-activated protein kinase 9. (354 aa)
LIMK1LIM domain kinase 1. (677 aa)
CD247CD247 molecule. (164 aa)
ENSMNEP00000036315Uncharacterized protein. (182 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
C7orf31Chromosome 7 open reading frame 31. (590 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
WEE1Wee1-like protein kinase. (646 aa)
ENSMNEP00000035333Ig-like domain-containing protein; Belongs to the MHC class I family. (356 aa)
GNB5G protein subunit beta 5. (409 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
ENSMNEP00000034709Uncharacterized protein. (439 aa)
ENSMNEP00000034688Uncharacterized protein. (288 aa)
FASLGTumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (597 aa)
TRAV22T cell receptor alpha variable 22. (147 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
ENSMNEP00000033181Ig-like domain-containing protein; Belongs to the MHC class I family. (393 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (487 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
HLA-FMajor histocompatibility complex, class I, F; Belongs to the MHC class I family. (440 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
STING1Transmembrane protein 173. (379 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
APOBEC3HApolipoprotein B mRNA editing enzyme catalytic subunit 3H. (211 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
RAC1Rac family small GTPase 1. (211 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
CD3GCD3g molecule. (209 aa)
APOBEC3GApolipoprotein B mRNA editing enzyme catalytic subunit 3G. (431 aa)
LOC105468609Uncharacterized protein. (488 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
GNAI1G protein subunit alpha i1. (422 aa)
TRIM6Tripartite motif containing 6. (559 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (391 aa)
TRACT cell receptor alpha constant. (110 aa)
PXNPaxillin. (1082 aa)
CALM3Calmodulin 3. (149 aa)
RBX1RING-type domain-containing protein. (108 aa)
ENSMNEP00000029248MHC_I-like_Ag-recog domain-containing protein. (172 aa)
LOC105498418Uncharacterized protein. (190 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
IFNB1Interferon beta 1. (187 aa)
ENSMNEP00000028956Uncharacterized protein. (185 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ENSMNEP00000028604IGv domain-containing protein. (139 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
IRF3Interferon regulatory factor 3. (422 aa)
ENSMNEP00000027902Protein kinase domain-containing protein. (365 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
CALM2Calmodulin 1; Belongs to the calmodulin family. (149 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
GNB3G protein subunit beta 3. (340 aa)
MANE-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LIMK2LIM domain kinase 2. (638 aa)
BST2Bone marrow stromal cell antigen 2. (182 aa)
GNB1G protein subunit beta 1. (340 aa)
CDC25CCell division cycle 25C. (507 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
GNAI3G protein subunit alpha i3. (328 aa)
CALML6Calmodulin like 6. (181 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
ENSMNEP00000023924MHC_I-like_Ag-recog domain-containing protein. (162 aa)
ELOBElongin B. (167 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (384 aa)
CUL4BCullin 4B; Belongs to the cullin family. (913 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (304 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSMNEP00000023427Uncharacterized protein. (198 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
LOC105469851Ig-like domain-containing protein; Belongs to the MHC class I family. (381 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
CCNB3Cyclin B3; Belongs to the cyclin family. (1363 aa)
AP1G1AP-1 complex subunit gamma. (825 aa)
CALRCalreticulin. (417 aa)
NFATC2Nuclear factor of activated T cells 2. (921 aa)
ENSMNEP00000021101Zf-rbx1 domain-containing protein. (93 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
GNAI2G protein subunit alpha i2. (355 aa)
CCDC125Coiled-coil domain containing 125. (510 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (196 aa)
ENSMNEP00000019824Uncharacterized protein. (194 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
RAC2Rac family small GTPase 2. (192 aa)
CD3DCD3d molecule. (171 aa)
ENSMNEP00000018745Ig-like domain-containing protein; Belongs to the MHC class I family. (317 aa)
CD3ECD3e molecule. (198 aa)
CALML4Calmodulin like 4. (193 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
ELOCElongin C; Belongs to the SKP1 family. (112 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
AP1B1AP complex subunit beta. (949 aa)
WEE2Wee1-like protein kinase. (568 aa)
ENSMNEP00000017370Uncharacterized protein; Belongs to the cyclin family. (341 aa)
PAK4Non-specific serine/threonine protein kinase. (702 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (409 aa)
AP1G2AP-1 complex subunit gamma. (785 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (421 aa)
ENSMNEP00000016854ADF-H domain-containing protein. (135 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
ENSMNEP00000016414Uncharacterized protein; Belongs to the calmodulin family. (179 aa)
BIDBH3 interacting domain death agonist. (266 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ENSMNEP00000013313Uncharacterized protein. (152 aa)
ENSMNEP00000013158Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
ENSMNEP00000013138Ig-like domain-containing protein; Belongs to the MHC class I family. (352 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
CCR5C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (379 aa)
NFATC4Nuclear factor of activated T cells 4. (961 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
ENSMNEP00000011545Uncharacterized protein. (81 aa)
TRIM5Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (484 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (693 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
ENSMNEP00000010486Ig-like domain-containing protein. (133 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNAQG protein subunit alpha q. (359 aa)
TAPBPTAP binding protein. (504 aa)
PLVAPPlasmalemma vesicle associated protein. (442 aa)
GNB2G protein subunit beta 2. (340 aa)
GNB4G protein subunit beta 4. (340 aa)
RAC3Rac family small GTPase 3. (192 aa)
PIK3R2Uncharacterized protein. (668 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC105466472Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa)
ENSMNEP00000007368MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (168 aa)
FASTumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa)
RNF7Ring finger protein 7. (113 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (361 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC105492342Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
NFATC3Nuclear factor of activated T cells 3. (1075 aa)
LOC105477715Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
ENSMNEP00000005141Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (717 aa)
LOC105495023Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (532 aa)
PAK2Non-specific serine/threonine protein kinase. (501 aa)
LOC105477037Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSMNEP00000004019Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
LOC105486922Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (435 aa)
NFATC1Nuclear factor of activated T cells 1. (988 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
BCL2L1BCL2 like 1. (233 aa)
ENSMNEP00000002738Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC105495842Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
TRIM22Tripartite motif containing 22. (498 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
TLR2Toll-like receptor. (784 aa)
HLA-GIGc1 domain-containing protein; Belongs to the MHC class I family. (354 aa)
LOC105497820Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105491771Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3032 aa)
IFNA6Interferon alpha 6. (190 aa)
ERASES cell expressed Ras. (233 aa)
LOC105487609Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
LOC105467297Ig-like domain-containing protein; Belongs to the MHC class I family. (242 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa)
MANE-BIg-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
PPP1R14BUncharacterized protein. (208 aa)
ENSMNEP00000045959Uncharacterized protein. (66 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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