(69 nodes) Chemical carcinogenesis network (Macaca nemestrina)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105470210	Uncharacterized protein; Belongs to the cytochrome P450 family. (489 aa)
	ALDH3B1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (534 aa)
	GSTM3	Glutathione S-transferase. (225 aa)
	ENSMNEP00000044246	Uncharacterized protein. (426 aa)
	LOC105477363	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
	LOC105463617	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
	GSTP1	Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator. (714 aa)
	ENSMNEP00000042658	annotation not available (67 aa)
	GSTK1	Glutathione S-transferase kappa. (226 aa)
	MGST1	Microsomal glutathione S-transferase 1. (155 aa)
	ALDH3B2	Aldehyde dehydrogenase 3 family member B2; Belongs to the aldehyde dehydrogenase family. (385 aa)
	ENSMNEP00000038667	Uncharacterized protein. (459 aa)
	LOC105483001	Sulfotransferase; Belongs to the sulfotransferase 1 family. (287 aa)
	EPHX1	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (477 aa)
	MGST3	Microsomal glutathione S-transferase 3. (166 aa)
	LOC105479949	Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
	LOC105482874	Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)
	LOC105481168	Uncharacterized protein; Belongs to the cytochrome P450 family. (329 aa)
	LOC105495313	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	ADH4	Alcohol dehydrogenase 4 (class II), pi polypeptide. (416 aa)
	HSD11B1	Hydroxysteroid 11-beta dehydrogenase 1. (292 aa)
	LOC105479916	Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
	SULT2A1	Sulfotransferase; Belongs to the sulfotransferase 1 family. (285 aa)
	LOC105477362	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
	CHRNA7	Uncharacterized protein. (510 aa)
	UGT2A3	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (527 aa)
	ENSMNEP00000029058	Uncharacterized protein. (98 aa)
	GSTA3	Glutathione S-transferase alpha 3. (222 aa)
	CYP1A1	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
	NAT1	N-acetyltransferase 1; Belongs to the arylamine N-acetyltransferase family. (352 aa)
	LOC105498674	Uncharacterized protein; Belongs to the cytochrome P450 family. (537 aa)
	ENSMNEP00000027418	Uncharacterized protein; Belongs to the GST superfamily. (202 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
	CYP2E1	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (494 aa)
	LOC105477366	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	LOC105497405	Uncharacterized protein. (240 aa)
	ADH6	Alcohol dehydrogenase 6 (class V). (374 aa)
	MGST2	Microsomal glutathione S-transferase 2. (147 aa)
	LOC105497406	GST N-terminal domain-containing protein. (67 aa)
	ENSMNEP00000021019	Glutathione S-transferase. (213 aa)
	UGT2A1	UDP glucuronosyltransferase family 2 member A1 complex locus; Belongs to the UDP-glycosyltransferase family. (693 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (604 aa)
	ENSMNEP00000019397	Uncharacterized protein. (279 aa)
	HPGDS	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
	HSD11B1L	Hydroxysteroid 11-beta dehydrogenase 1 like. (300 aa)
	ADH7	Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide. (394 aa)
	GSTO2	Glutathione S-transferase omega 2; Belongs to the GST superfamily. (243 aa)
	ENSMNEP00000017251	Uncharacterized protein. (311 aa)
	LOC105477045	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
	LOC105497389	Uncharacterized protein. (503 aa)
	KYAT1	Aminotran_1_2 domain-containing protein. (512 aa)
	GSTO1	Uncharacterized protein; Belongs to the GST superfamily. (252 aa)
	ADH5	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
	UGT1A1	UDP glucuronosyltransferase family 1 member A1; Belongs to the UDP-glycosyltransferase family. (570 aa)
	CYP3A5	Cytochrome P450 family 3 subfamily A member 5. (503 aa)
	ENSMNEP00000008644	Uncharacterized protein. (322 aa)
	ALDH3A1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (480 aa)
	GSTM4	Glutathione S-transferase mu 4; Belongs to the GST superfamily. (218 aa)
	GSTT2B	Uncharacterized protein; Belongs to the GST superfamily. (244 aa)
	CYP3A43	Cytochrome P450 family 3 subfamily A member 43. (503 aa)
	CYP1A2	Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (516 aa)
	ADH1A	Alcohol dehydrogenase 1A (class I), alpha polypeptide. (374 aa)
	ENSMNEP00000004090	Uncharacterized protein; Belongs to the cytochrome P450 family. (175 aa)
	GSTA4	Glutathione S-transferase alpha 4. (222 aa)
	KYAT3	Kynurenine aminotransferase 3. (454 aa)
	LOC105470207	Uncharacterized protein. (467 aa)
	ENSMNEP00000000907	Uncharacterized protein. (241 aa)
	LOC105470206	Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADH1A	ADH7	ENSMNEP00000005435	ENSMNEP00000018247	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide.	0.546
ADH1A	ALDH3A1	ENSMNEP00000005435	ENSMNEP00000007851	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.999
ADH1A	ALDH3B1	ENSMNEP00000005435	ENSMNEP00000044622	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.999
ADH1A	ALDH3B2	ENSMNEP00000005435	ENSMNEP00000038675	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Aldehyde dehydrogenase 3 family member B2; Belongs to the aldehyde dehydrogenase family.	0.908
ADH1A	CYP2E1	ENSMNEP00000005435	ENSMNEP00000025973	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	0.999
ADH1A	ENSMNEP00000000907	ENSMNEP00000005435	ENSMNEP00000000907	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Uncharacterized protein.	0.545
ADH1A	ENSMNEP00000021019	ENSMNEP00000005435	ENSMNEP00000021019	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Glutathione S-transferase.	0.414
ADH1A	ENSMNEP00000042658	ENSMNEP00000005435	ENSMNEP00000042658	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	annotation not available	0.521
ADH1A	GSTA3	ENSMNEP00000005435	ENSMNEP00000028936	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Glutathione S-transferase alpha 3.	0.751
ADH1A	GSTA4	ENSMNEP00000005435	ENSMNEP00000003867	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Glutathione S-transferase alpha 4.	0.752
ADH1A	GSTK1	ENSMNEP00000005435	ENSMNEP00000042555	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Glutathione S-transferase kappa.	0.758
ADH1A	GSTM3	ENSMNEP00000005435	ENSMNEP00000044309	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Glutathione S-transferase.	0.862
ADH1A	GSTM4	ENSMNEP00000005435	ENSMNEP00000007721	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Glutathione S-transferase mu 4; Belongs to the GST superfamily.	0.835
ADH1A	GSTO1	ENSMNEP00000005435	ENSMNEP00000014207	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Uncharacterized protein; Belongs to the GST superfamily.	0.864
ADH1A	GSTO2	ENSMNEP00000005435	ENSMNEP00000017342	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Glutathione S-transferase omega 2; Belongs to the GST superfamily.	0.864
ADH1A	GSTP1	ENSMNEP00000005435	ENSMNEP00000043232	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Glutathione S-transferase pi 1; Belongs to the GST superfamily.	0.877
ADH1A	GSTT2B	ENSMNEP00000005435	ENSMNEP00000007488	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Uncharacterized protein; Belongs to the GST superfamily.	0.760
ADH1A	HPGDS	ENSMNEP00000005435	ENSMNEP00000019062	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.	0.874
ADH1A	LOC105463617	ENSMNEP00000005435	ENSMNEP00000044184	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.748
ADH1A	LOC105477362	ENSMNEP00000005435	ENSMNEP00000030637	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.860